A New Dermatological Availability of the Flavonoid Fraction from Licorice Roots-Effect on Acne-

DOI
  • Kambara Toshimitsu
    Research & Development Division, Research Center, Maruzen Pharmaceuticals Co., Ltd.
  • Zhou Yanyang
    Research & Development Division, Research Center, Maruzen Pharmaceuticals Co., Ltd.
  • Kawashima Yoshihito
    Research & Development Division, Research Center, Maruzen Pharmaceuticals Co., Ltd.
  • Kishida Naoko
    Research & Development Division, Research Center, Maruzen Pharmaceuticals Co., Ltd.
  • Mizutani Kenji
    Research & Development Division, Research Center, Maruzen Pharmaceuticals Co., Ltd.
  • Ikeda Takao
    Research & Development Division, Research Center, Maruzen Pharmaceuticals Co., Ltd.
  • Kameyama Koichiro
    Aoyama Dermatological Clinic

Bibliographic Information

Other Title
  • 甘草フラボノイド画分の新たな皮膚科学的有用性　　ニキビに対する効果
  • Effect on Acne
  • ニキビに対する効果

Description

In the course of our studies on the further application of licorice as a cosmetic ingredient, we studied a new dermatological availability in the licorice extract containing licochalcone-A as a main principle, Polyol Soluble Licorice Extract P-U, prepared from the roots of Glycyrrhiza inflata Batalin. As a result, this extract showed several activities such as inhibitory actions of testosterone 5α-reductase, lipase and phospholipase A2, as well as androgen receptor antagonist, antimicrobial and SOD-like actions, which relate to skin care, especially the suppression of acne formation and development. On basis of this evidence, a trial of Polyol Soluble Licorice Extract P-U with acne patients was carried out and the efficacy was demonstrated clinically.

Journal

Keywords

Details 詳細情報について

  • CRID
    1390001204501555328
  • NII Article ID
    130004188863
  • DOI
    10.5107/sccj.37.3_179
  • ISSN
    18844146
    03875253
  • Text Lang
    ja
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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