Development of polymeric micelles for innovative photodynamic therapy
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- Nishiyama Nobuhiro
- Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo
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- Morimoto Yuji
- Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College
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- Kataoka Kazunori
- Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo Department of Materials Engineering, Graduate School of Engineering, The University of Tokyo
Bibliographic Information
- Other Title
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- ダブルターゲティング:薬物と医療機器テクノロジーの融合 革新的光線力学療法のための高分子ミセル型DDSの設計
- 革新的光線力学療法のための高分子ミセル型DDSの設計
- カクシンテキ コウセン リキガク リョウホウ ノ タメ ノ コウブンシ ミセルガタ DDS ノ セッケイ
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Description
Photodynamic therapy (PDT) is an effective method for the treatment of superficial and early-stage cancers. The use of DDS for the delivery of photosensitizers is a promising approach for improved safety and enhanced efficacy of PDT. In this regard, we have developed polymeric micelles incorporating dendritic photosensitizers and demonstrated their usefulness in animal studies.<BR>Also, we have established an innovative PDT system using the combination of polymeric micelles and light irradiation device for diagnosis and treatment of microcarcinoma.
Journal
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- Drug Delivery System
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Drug Delivery System 25 (5), 448-455, 2010
THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM
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Details 詳細情報について
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- CRID
- 1390001204641633408
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- NII Article ID
- 10026692752
- 130000405538
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- NII Book ID
- AN10084591
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- COI
- 1:CAS:528:DC%2BC3cXhsVersrbK
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- ISSN
- 18812732
- 09135006
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- NDL BIB ID
- 10864524
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed