A CASE REPORT OF GRANULOMATOUS MASTITIS WITH ERYTHEMA NODOSUM

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  • 結節性紅斑を合併した肉芽腫性乳腺炎の１例

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We report a case of a 41-year-old woman with granulomatous mastitis and erythema nodosum. An elastic hard painful mass 3.8cm in diameter was palpable at the C area of the right breast. Ultrasound examination revealed an irregular hypo-echoic mass and mammography showed an asymmetric shadow. Fine needle aspiration biopsy showed only inflammatory changes without malignancy. A possibility of malignancy could not be ruled out, so excisional biopsies were performed. The pathologic diagnosis was granulomatous mastitis. After a month, she presented erythematous nodules of the leg. She was treated with oral predonisolone, 10mg/day, followed by tapering of the dose. The skin lesions rapidly disappeared. The breast lesion then gradually improved and almost disappeared by four months after the start of treatment. To our knowledge, 6 cases of granulomatous mastitis with erythema nodosum have been reported in the literature, and this is the second report of granulomatous mastitis with erythema nodosum in Japan.

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