{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390001204867548288.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.2169/internalmedicine.42.1240"}},{"identifier":{"@type":"COI","@value":"1:STN:280:DC%2BD2c%2FhslCruw%3D%3D"}},{"identifier":{"@type":"PMID","@value":"14714967"}},{"identifier":{"@type":"NDL_BIB_ID","@value":"6794891"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/bib/6794891"}},{"identifier":{"@type":"URI","@value":"https://ndlsearch.ndl.go.jp/books/R000000004-I6794891"}},{"identifier":{"@type":"URI","@value":"http://www.jstage.jst.go.jp/article/internalmedicine1992/42/12/42_12_1240/_pdf"}},{"identifier":{"@type":"NAID","@value":"130000767039"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2004126975"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@language":"en","@value":"Predictive Value of Serial Platelet Count and VEGF Determination for the Management of DIC in the Crow-Fukase (POEMS) Syndrome"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"We report a case of a 62-year-old man diagnosed as Crow-Fukase syndrome (POEMS syndrome), in which the serial platelet count and vascular endothelial growth factor (VEGF) concentration were determined before and during the state of disseminated intravascular coagulation (DIC). The serum VEGF concentration was noted to be gradually decreased prior to DIC, after which it abruptly decreased with a corresponding drop in platelet count upon the onset of DIC. The physiological effects of VEGF are viewed as one of the causative factors in DIC and its abrupt and excessive release may have caused the exacerbation of the patient's clinical symptoms.<br>(Internal Medicine 42: 1240-1243, 2003)"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1420564276170498432","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"10336365"},{"@type":"NRID","@value":"1000010336365"},{"@type":"NRID","@value":"9000003169888"},{"@type":"NRID","@value":"9000010287178"},{"@type":"NRID","@value":"9000018484345"},{"@type":"NRID","@value":"9000257740251"},{"@type":"NRID","@value":"9000003920940"},{"@type":"NRID","@value":"9000253539009"},{"@type":"NRID","@value":"9000001013033"},{"@type":"NRID","@value":"9000283409495"},{"@type":"NRID","@value":"9000022288949"},{"@type":"NRID","@value":"9000356569840"},{"@type":"NRID","@value":"9000314803759"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0097725"}],"foaf:name":[{"@language":"en","@value":"TOKASHIKI Takashi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The Third Department of Internal Medicine, Kagoshima University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204867548292","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000000561159"}],"foaf:name":[{"@language":"en","@value":"HASHIGUCHI Teruto"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The Department of Laboratory Medicine, Kagoshima University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204867548293","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000004726346"}],"foaf:name":[{"@language":"en","@value":"ARIMURA Kimiyoshi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The Third Department of Internal Medicine, Kagoshima University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204867548288","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000018484346"}],"foaf:name":[{"@language":"en","@value":"EIRAKU Nobutaka"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The Third Department of Internal Medicine, Kagoshima 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Mitsuhiro"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The Third Department of Internal Medicine, Kagoshima University"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"09182918"},{"@type":"EISSN","@value":"13497235"},{"@type":"NDL_BIB_ID","@value":"000000152230"},{"@type":"ISSN","@value":"09182918"},{"@type":"LISSN","@value":"09182918"},{"@type":"PISSN","@value":"https://id.crossref.org/issn/09182918"},{"@type":"NCID","@value":"AA10827774"}],"prism:publicationName":[{"@language":"en","@value":"Internal Medicine"},{"@language":"en","@value":"Intern. Med."}],"dc:publisher":[{"@language":"en","@value":"The Japanese Society of Internal Medicine"},{"@language":"ja","@value":"一般社団法人 日本内科学会"}],"prism:publicationDate":"2003","prism:volume":"42","prism:number":"12","prism:startingPage":"1240","prism:endingPage":"1243"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"http://id.ndl.go.jp/bib/6794891"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I6794891"},{"@id":"http://www.jstage.jst.go.jp/article/internalmedicine1992/42/12/42_12_1240/_pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2004126975"}],"availableAt":"2003","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Crow-Fukase%20syndrome","dc:title":"Crow-Fukase syndrome"},{"@id":"https://cir.nii.ac.jp/all?q=vascular%20endothelial%20growth%20factor","dc:title":"vascular endothelial growth factor"},{"@id":"https://cir.nii.ac.jp/all?q=vascular%20permeability%20factor","dc:title":"vascular permeability factor"},{"@id":"https://cir.nii.ac.jp/all?q=VPF","dc:title":"VPF"},{"@id":"https://cir.nii.ac.jp/all?q=coagulation","dc:title":"coagulation"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360011145618058624","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"Growth factors in POEMS syndrome: Evidence for a marked increase in circulating vascular endothelial growth factor"}]},{"@id":"https://cir.nii.ac.jp/crid/1360023718184151424","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024: part 4—trauma, burn, obstetrics, acute pancreatitis/liver failure, and others"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285711813209728","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"POEMS syndrome and calciphylaxis: an unrecognized cause of abnormal small vessel calcification"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848654819827840","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Clonal immunoglobulin λ light‐chain gene rearrangements detected by next generation sequencing in POEMS syndrome"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855569256519040","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"Acute Arterial Obliteration: A New Feature of the POEMS Syndrome?"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418519056865920","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418519793317760","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825893791658112","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204240608384","@type":"Article","relationType":["isReferencedBy","isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Recurrent Crow-Fukase Syndrome Associated with Increased Serum Levels of Vascular Endothelial Growth Factor: A Case Report and Review of the Literature"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679845259008","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"VEGF Is Causative for Pulmonary Hypertension in a Patient with Crow-Fukase (POEMS) Syndrome."}]},{"@id":"https://cir.nii.ac.jp/crid/1570009750051564672","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Overproduction of vascular endothelial growth factor/vascular permeability factor is causative in Crow-Fukase (POEMS) syndrome"}]},{"@id":"https://cir.nii.ac.jp/crid/1570009750051567488","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Beneficial treatment of argatroban on polyneuropathy associated with Crow-Fukase syndrome. A case report"}]},{"@id":"https://cir.nii.ac.jp/crid/1570572699966376320","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Greatly raised vascular endothelial growth factor (VEGF) in POEMS syndrome"}]},{"@id":"https://cir.nii.ac.jp/crid/1571698599750888192","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Release of the angiogenic cytokine vascular endothelial growth factor (VEGF) from platelets : significance for VEGF measurements and cancer biology"}]},{"@id":"https://cir.nii.ac.jp/crid/1571698599800453632","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Highly concentrated vascular endothelial growth factor in platelets in Crow-Fukase syndrome"}]},{"@id":"https://cir.nii.ac.jp/crid/1571980074881262336","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Coagulation and vascular abnormalities in Crow-Fukase syndrome"}]},{"@id":"https://cir.nii.ac.jp/crid/1571980074888543744","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Vascular endothelial growth factor (VEGF) is released from platelets during blood clotting : implications for measurement of circulating VEGF levels in clinical disease"}]},{"@id":"https://cir.nii.ac.jp/crid/1572543024803766912","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"In vitro release of vascular endothelial growth factor during platelet aggregation"}]},{"@id":"https://cir.nii.ac.jp/crid/1572543026341310848","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"POWMS syndrome with vascular lesions : a role for interleukin-1beta and interleukin-6 in crease-a case report"}]},{"@id":"https://cir.nii.ac.jp/crid/1573105974795383936","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Improvement of parameters concerning blood coagulation and complement systems in a case of Crow-Fukase syndrome"}]},{"@id":"https://cir.nii.ac.jp/crid/1573668924637431168","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"The Crow-Fukase syndrome : A study of 102 cases in Japan"}]}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:0023514138"},{"@type":"NDL_SEARCH","@value":"oai:ndlsearch.ndl.go.jp:R000000004-I6794891"},{"@type":"CROSSREF","@value":"10.2169/internalmedicine.42.1240"},{"@type":"PUBMED","@value":"14714967"},{"@type":"CIA","@value":"130000767039"},{"@type":"OPENAIRE","@value":"doi_dedup___::17864bb96ab140f003dd58a598bc5ad5"},{"@type":"CROSSREF","@value":"10.1007/s12185-025-03918-0_references_DOI_9bT7EAJZy7mNRAAYAZpj8Sp9Uiz"},{"@type":"CROSSREF","@value":"10.1186/s13023-016-0421-3_references_DOI_9bT7EAJZy7mNRAAYAZpj8Sp9Uiz"},{"@type":"CROSSREF","@value":"10.1002/ajh.25213_references_DOI_9bT7EAJZy7mNRAAYAZpj8Sp9Uiz"},{"@type":"CROSSREF","@value":"10.1620/tjem.210.269_references_DOI_9bT7EAJZy7mNRAAYAZpj8Sp9Uiz"}]}