{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390001205106932480.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1253/circj.cj-15-0106"}},{"identifier":{"@type":"PMID","@value":"25746531"}},{"identifier":{"@type":"DOI","@value":"10.1253/circj.cj-14-0932"}},{"identifier":{"@type":"PMID","@value":"25746547"}},{"identifier":{"@type":"NDL_BIB_ID","@value":"026187137"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/bib/026187137"}},{"identifier":{"@type":"URI","@value":"https://ndlsearch.ndl.go.jp/books/R000000004-I026187137"}},{"identifier":{"@type":"URI","@value":"https://www.jstage.jst.go.jp/article/circj/79/3/79_CJ-14-0932/_pdf"}},{"identifier":{"@type":"URI","@value":"https://www.jstage.jst.go.jp/article/circj/79/3/79_CJ-15-0106/_pdf"}},{"identifier":{"@type":"NAID","@value":"130004927121"}},{"identifier":{"@type":"NAID","@value":"130004927085"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2015297223"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@language":"en","@value":"Assessment of Coronary Flow Reserve by Dynamic Single-Photon Emission Computed Tomography"},{"@value":"Prediction of Left Main or 3-Vessel Disease Using Myocardial Perfusion Reserve on Dynamic Thallium-201 Single-Photon Emission Computed Tomography With a Semiconductor Gamma Camera"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"<b><i>Background:</i></b>Myocardial perfusion imaging (MPI) may fail to detect balanced ischemia. We evaluated myocardial perfusion reserve (MPR) using Tl dynamic single-photon emission computed tomography (SPECT) and a novel cadmium zinc telluride (CZT) camera for predicting 3-vessel or left main coronary artery disease (CAD).<b><i>Methods and Results:</i></b>A total of 55 consecutive patients with suspected CAD underwent SPECT-MPI and coronary angiography. The MPR index was calculated using the standard 2-compartment kinetic model. We analyzed the utility of MPR index, other SPECT findings, and various clinical variables. On multivariate analysis, MPR index and history of previous myocardial infarction (MI) predicted left main and 3-vessel disease. The area under the receiver operating characteristic curve was 0.81 for MPR index, 0.699 for history of previous MI, and 0.86 for MPR index plus history of previous MI. MPR index ≤1.5 yielded the highest diagnostic accuracy. Sensitivity, specificity, and accuracy were 86%, 78%, and 80%, respectively, for MPR index, 64%, 76%, 73% for previous MI, and 57%, 93%, and 84% for MPR index plus history of previous MI.<b><i>Conclusions:</i></b>Quantification of MPR using dynamic SPECT and a novel CZT camera may identify balanced ischemia in patients with left main or 3-vessel disease.  (<i>Circ J</i> 2015; <b>79:</b> 623–631)"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1030003658696160641","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"20455637"},{"@type":"NRID","@value":"1000020455637"},{"@type":"NRID","@value":"9000005855983"},{"@type":"NRID","@value":"9000404101334"},{"@type":"NRID","@value":"9000283560955"},{"@type":"NRID","@value":"9000351082852"},{"@type":"NRID","@value":"9000369746156"},{"@type":"NRID","@value":"9000390890861"},{"@type":"NRID","@value":"9000411206455"},{"@type":"NRID","@value":"9000398292626"},{"@type":"NRID","@value":"9000406302510"},{"@type":"NRID","@value":"9000390413405"},{"@type":"NRID","@value":"9000326661571"},{"@type":"NRID","@value":"9000404098848"},{"@type":"NRID","@value":"9000404537344"},{"@type":"NRID","@value":"9000404098832"},{"@type":"NRID","@value":"9000415343348"},{"@type":"NRID","@value":"9000327099289"},{"@type":"NRID","@value":"9000415048580"},{"@type":"NRID","@value":"9000402259521"},{"@type":"NRID","@value":"9000351082267"},{"@type":"NRID","@value":"9000411393583"},{"@type":"NRID","@value":"9000369746165"},{"@type":"NRID","@value":"9000415227147"},{"@type":"NRID","@value":"9000298901000"},{"@type":"NRID","@value":"9000362202826"},{"@type":"NRID","@value":"9000365540469"},{"@type":"NRID","@value":"9000404098869"},{"@type":"NRID","@value":"9000283561415"},{"@type":"NRID","@value":"9000398292612"},{"@type":"NRID","@value":"9000369746128"},{"@type":"NRID","@value":"9000413569450"},{"@type":"NRID","@value":"9000259832122"},{"@type":"NRID","@value":"9000399524435"},{"@type":"NRID","@value":"9000415230045"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/pet"}],"foaf:name":[{"@language":"en","@value":"Naya Masanao"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001205106932481","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000283561416"}],"foaf:name":[{"@language":"en","@value":"Tsutsui Hiroyuki"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"13469843"},{"@type":"LISSN","@value":"13469843"},{"@type":"EISSN","@value":"13474820"},{"@type":"NDL_BIB_ID","@value":"000000402515"},{"@type":"ISSN","@value":"13469843"},{"@type":"NCID","@value":"AA11591968"}],"prism:publicationName":[{"@language":"en","@value":"Circulation Journal"},{"@language":"en","@value":"Circ J"}],"dc:publisher":[{"@language":"en","@value":"The Japanese Circulation Society"},{"@language":"ja","@value":"一般社団法人 日本循環器学会"}],"prism:publicationDate":"2015","prism:volume":"79","prism:number":"3","prism:startingPage":"515","prism:endingPage":"516"},"reviewed":"false","url":[{"@id":"http://id.ndl.go.jp/bib/026187137"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I026187137"},{"@id":"https://www.jstage.jst.go.jp/article/circj/79/3/79_CJ-14-0932/_pdf"},{"@id":"https://www.jstage.jst.go.jp/article/circj/79/3/79_CJ-15-0106/_pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2015297223"}],"availableAt":"2015","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Balanced%20ischemia","dc:title":"Balanced ischemia"},{"@id":"https://cir.nii.ac.jp/all?q=Myocardial%20perfusion%20reserve","dc:title":"Myocardial perfusion reserve"},{"@id":"https://cir.nii.ac.jp/all?q=Semiconductor%20gamma%20camera","dc:title":"Semiconductor gamma camera"},{"@id":"https://cir.nii.ac.jp/all?q=Thallium-201","dc:title":"Thallium-201"},{"@id":"https://cir.nii.ac.jp/all?q=Three-vessel%20disease","dc:title":"Three-vessel disease"}],"project":[{"@id":"https://cir.nii.ac.jp/crid/1040000782304526208","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"26461858"},{"@type":"JGN","@value":"JP26461858"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26461858/"}],"notation":[{"@language":"ja","@value":"負荷心筋スペクトにおける心筋摂取率の有用性に関する研究"},{"@language":"en","@value":"research on usefulness of myocardial uptake index on stress myocardial perfusion SPECT"}]},{"@id":"https://cir.nii.ac.jp/crid/1040000782304532352","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"26461859"},{"@type":"JGN","@value":"JP26461859"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26461859/"}],"notation":[{"@language":"ja","@value":"心臓専用半導体SPECT装置を用いた心筋血流量及び冠血管予備能の定量化と臨床応用"},{"@language":"en","@value":"Quantification and validation of myocardial blood flow and flow reserve using a semiconductor gamma camera;"}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360002215368689920","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Comparison of conventional and cadmium–zinc–telluride single-photon emission computed tomography for analysis of thallium-201 myocardial perfusion imaging: an exploratory study in normal databases for different 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