Mild Laxative and QOL-improving Effects of Kiwi Fruit Extract in the Elderly -An Explanatory Study on Effectiveness and Safety-

  • UEBABA Kazuo
    Institute of Natural Medicine, University of Toyama
  • URATA Tetsuro
    Urata Clinic, Medical Cooperation Hospital
  • SUZUKI Nobutaka
    Department of Complementary and Alternative Medicine Clinical Research and Development, Kanazawa University Graduate School of Medical Science
  • ARAI Takanari
    Endowed Center for the Advancement of Pregnancy, Perinatal and Infant Care, Kanazawa University Graduate School of Medical Science
  • STRONG Jeffry Michael
    Department of Complementary and Alternative Medicine Clinical Research and Development, Kanazawa University Graduate School of Medical Science
  • OONO Satoshi
    Department of Complementary and Alternative Medicine Clinical Research and Development, Kanazawa University Graduate School of Medical Science
  • HAYASHI Hirotaka
    Department of Complementary and Alternative Medicine Clinical Research and Development, Kanazawa University Graduate School of Medical Science Innovation Development Center, Kanazawa University

Bibliographic Information

Other Title
  • キウイ果汁エキス食品の高齢者における便通促進と QOL 増進効果  ‐効果と安全性についての探索的検討‐
  • キウイ果汁エキス食品の高齢者における便通促進とQOL増進効果--効果と安全性についての探索的検討
  • キウイ カジュウ エキス ショクヒン ノ コウレイシャ ニ オケル ベンツウ ソクシン ト QOL ゾウシン コウカ コウカ ト アンゼンセイ ニ ツイテ ノ タンサクテキ ケントウ
  • —An Explanatory Study on Effectiveness and Safety—
  • ―効果と安全性についての探索的検討―

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Abstract

Fresh kiwi fruit freeze-dried juice has been traditionally used for constipation of elderly patients. Its effectiveness and safety was studied in 42 elderly patients (age 60–84: median age 67±6) suffering from mild to moderate constipation, taken as a food supplement of 6 capsules/3 times per day for 4 weeks following a one week control period, after receiving written informed consent. Bowel habits and generic quality of life questionnaires were monitored. Bowel habits such as evacuation time and stool quality improved from the 14th day and continued for 28 days compared to the control period.<br> Quality of life in terms of external appearance (such as skin and edema), lumbago, and headache improved. In conclusion, freeze-dried fresh kiwi fruit juice had a laxative and QOL-improving effect on the elderly. No apparent adverse effects were observed.<br>

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