{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390001205221165056.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.5981/jjhnc.39.55"}},{"identifier":{"@type":"NAID","@value":"130004940748"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2013279858"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@language":"en","@value":"Salvage surgery for recurrence of hypopharyngeal carcinoma after definitive radiotherapy or chemoradiotherapy"},{"@language":"ja","@value":"下咽頭癌放射線治療後局所再発・残存に対する救済手術例の検討"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"The aim of this study was to analyze the efficacy of salvage surgery for patients with recurrent hypopharyngeal carcinoma after definitive radiotherapy (RT) or chemoradiotherapy (CRT).<br>From April 2001 to August 2010, 101 patients with hypopharyngeal carcinoma underwent definitive RT or CRT at the University of Tokyo Hospital. Local recurrence developed in 35 patients (35%), of whom 24 patients underwent salvage surgery. <br>The types of surgical procedures were as follows: total pharyngolaryngectomy: 20, partial pharyngectomy: 3, and endoscopic pharyngo-laryngo surgery (ELPS): 1.<br>Three-year overall survival after salvage surgery was 60%. The median survival period was 38 months. Among these patients, postoperative complications occurred in 11 patients (46%).<br>Salvage surgery for recurrent hypopharyngeal carcinoma after definitive RT or CRT is effective for not only for the patients' quality of life, but also for the improvement of prognosis."},{"@language":"ja","@value":"（化学）放射線治療後の局所再発・残存に対し救済手術を施行した下咽頭癌症例について，その治療意義を明らかにする事を目的に検討した。<br>2001年4月から2010年8月の間に当科で初回治療として根治的（化学）放射線治療を行った下咽頭癌101例中，局所再発・残存を35例（35%）に認めた。内，救済手術を行いえた24例を対象として後向きに検討した。初回照射線量は69～72Gy，化学療法は同時/導入/なし：8/7/9例であった。<br>救済術式は咽喉食摘術/下咽頭部分切除術/内視鏡的咽喉頭手術（ELPS）：20/3/1例，術後観察期間は1～115ヶ月（平均30ヶ月），術後3年生存率は60%であった。一方，術後合併症は11例（46%）で起きていた。<br>一般に救済手術の予後は不良とされるが，比較的切除安全域を取りやすい下咽頭癌での救済手術は生命予後の改善に意義があると考えられた。"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1420001326205322240","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"00601139"},{"@type":"NRID","@value":"1000000601139"},{"@type":"NRID","@value":"9000283592848"},{"@type":"NRID","@value":"9000311508519"},{"@type":"NRID","@value":"9000399515137"},{"@type":"NRID","@value":"9000308729473"},{"@type":"NRID","@value":"9000243895869"},{"@type":"NRID","@value":"9000309999410"}],"foaf:name":[{"@language":"en","@value":"Omura Go"},{"@language":"ja","@value":"小村 豪"}],"jpcoar:affiliationName":[{"@language":"en","@value":"東京大学医学部耳鼻咽喉科・頭頸部外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290696401960576","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000259322978"}],"foaf:name":[{"@language":"en","@value":"Saito Yuki"},{"@language":"ja","@value":"齊藤 祐毅"}],"jpcoar:affiliationName":[{"@language":"en","@value":"東京大学医学部耳鼻咽喉科・頭頸部外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290696401960450","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000283592850"}],"foaf:name":[{"@language":"en","@value":"Yoshida Masahumi"},{"@language":"ja","@value":"吉田 昌史"}],"jpcoar:affiliationName":[{"@language":"en","@value":"東京大学医学部耳鼻咽喉科・頭頸部外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1420564276176353280","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"60511467"},{"@type":"NRID","@value":"1000060511467"},{"@type":"NRID","@value":"9000001139000"},{"@type":"NRID","@value":"9000404513420"},{"@type":"NRID","@value":"9000380461675"},{"@type":"NRID","@value":"9000413572910"},{"@type":"NRID","@value":"9000413247572"},{"@type":"NRID","@value":"9000018281158"},{"@type":"NRID","@value":"9000414923133"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/mizando"}],"foaf:name":[{"@language":"en","@value":"Ando Mizuo"},{"@language":"ja","@value":"安藤 瑞生"}],"jpcoar:affiliationName":[{"@language":"en","@value":"東京大学医学部耳鼻咽喉科・頭頸部外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290696401960451","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000283592852"}],"foaf:name":[{"@language":"en","@value":"Ebihara Yasuhiro"},{"@language":"ja","@value":"蝦原 康宏"}],"jpcoar:affiliationName":[{"@language":"en","@value":"東京大学医学部耳鼻咽喉科・頭頸部外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290696401960448","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000283592853"}],"foaf:name":[{"@language":"en","@value":"Asakage Takahiro"},{"@language":"ja","@value":"朝蔭 孝宏"}],"jpcoar:affiliationName":[{"@language":"en","@value":"東京大学医学部耳鼻咽喉科・頭頸部外科"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"13495747"},{"@type":"EISSN","@value":"18818382"}],"prism:publicationName":[{"@language":"en","@value":"Toukeibu Gan"},{"@language":"ja","@value":"頭頸部癌"},{"@language":"en","@value":"Toukeibu Gan"},{"@language":"ja","@value":"頭頸部癌"}],"dc:publisher":[{"@language":"en","@value":"Japan Society for Head and Neck Cancer"},{"@language":"ja","@value":"日本頭頸部癌学会"}],"prism:publicationDate":"2013","prism:volume":"39","prism:number":"1","prism:startingPage":"55","prism:endingPage":"59"},"reviewed":"false","url":[{"@id":"https://search.jamas.or.jp/link/ui/2013279858"}],"availableAt":"2013","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Hypopharyngeal%20carcinoma","dc:title":"Hypopharyngeal carcinoma"},{"@id":"https://cir.nii.ac.jp/all?q=Recurrence","dc:title":"Recurrence"},{"@id":"https://cir.nii.ac.jp/all?q=Salvage%20surgery","dc:title":"Salvage surgery"},{"@id":"https://cir.nii.ac.jp/all?q=Radiotherapy","dc:title":"Radiotherapy"},{"@id":"https://cir.nii.ac.jp/all?q=Chemoradiotherapy","dc:title":"Chemoradiotherapy"},{"@id":"https://cir.nii.ac.jp/all?q=%E4%B8%8B%E5%92%BD%E9%A0%AD%E7%99%8C","dc:title":"下咽頭癌"},{"@id":"https://cir.nii.ac.jp/all?q=%E5%86%8D%E7%99%BA","dc:title":"再発"},{"@id":"https://cir.nii.ac.jp/all?q=%E6%95%91%E6%B8%88%E6%89%8B%E8%A1%93","dc:title":"救済手術"},{"@id":"https://cir.nii.ac.jp/all?q=%E6%94%BE%E5%B0%84%E7%B7%9A%E7%99%82%E6%B3%95","dc:title":"放射線療法"},{"@id":"https://cir.nii.ac.jp/all?q=%E5%8C%96%E5%AD%A6%E6%94%BE%E5%B0%84%E7%B7%9A%E7%99%82%E6%B3%95","dc:title":"化学放射線療法"}],"project":[{"@id":"https://cir.nii.ac.jp/crid/1040282257208121472","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"24791750"},{"@type":"JGN","@value":"JP24791750"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24791750/"}],"notation":[{"@language":"ja","@value":"頭頸部扁平上皮癌におけるＤｏｃｅｔａｘｅｌの感受性予測についての検討"},{"@language":"en","@value":"Prediction 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