{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390001205257209856.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.3123/jemsge.28.167"}},{"identifier":{"@type":"NDL_BIB_ID","@value":"8684370"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/bib/8684370"}},{"identifier":{"@type":"URI","@value":"https://ndlsearch.ndl.go.jp/books/R000000004-I8684370"}},{"identifier":{"@type":"NAID","@value":"130004481146"}},{"identifier":{"@type":"NAID","@value":"110005717027"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2007190225"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@language":"en","@value":"Establishment of Reporter Yeasts for Guinea Pig and Syrian Hamster Aryl Hydrocarbon Receptor Ligand Activity"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"Polymorphism of the aryl hydrocarbon receptor (AhR) presumably induces genetic difference in the susceptibility of animals to aryl hydrocarbons. The activation of intracellular signaling following AhR binding to aryl hydrocarbons is highly correlated with the toxicity and carcinogenicity of these chemicals. Here we developed two reporter yeasts coexpressing AhR and AhR nuclear translocator (Arnt) proteins of a guinea pig and a Syrian hamster, known as the most sensitive and most resistant laboratory rodents to 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin (TCDD), respectively. We previously constructed reporter yeasts expressing human and mouse AhR/Arnt. We conducted reporter assays to measure ligand activities of TCDD, 3-methylcholanthrene, β-naphthoflavone and indirubin in these yeasts. Ligand treatment induced a dose-dependent increase in β-galactosidase activity from a reporter plasmid in all 4 yeast strains. The assays showed that yeast expressing guinea pig AhR/Arnt is most sensitive and yeast expressing Syrian hamster AhR/Arnt is most insensitive to these ligands. The yeasts expressing human and mouse AhR/Arnt were in-between. These different ligand activities reflect the species specificity of AhR/Arnt, and may be related to the susceptibility of rodents to aryl hydrocarbons.<br>"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1420001326223739008","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"70332963"},{"@type":"NRID","@value":"1000070332963"},{"@type":"NRID","@value":"9000014611520"},{"@type":"NRID","@value":"9000363399634"},{"@type":"NRID","@value":"9000363399595"},{"@type":"NRID","@value":"9000255723718"},{"@type":"NRID","@value":"9000363399614"},{"@type":"NRID","@value":"9000257967103"},{"@type":"NRID","@value":"9000018362446"},{"@type":"NRID","@value":"9000363399618"},{"@type":"NRID","@value":"9000363399645"},{"@type":"NRID","@value":"9000363399460"},{"@type":"NRID","@value":"9000363399524"},{"@type":"NRID","@value":"9000006939400"},{"@type":"NRID","@value":"9000363399476"},{"@type":"NRID","@value":"9000006939411"},{"@type":"NRID","@value":"9000360556413"},{"@type":"NRID","@value":"9000363399441"},{"@type":"NRID","@value":"9000363399510"},{"@type":"NRID","@value":"9000242882805"},{"@type":"NRID","@value":"9000363399619"},{"@type":"NRID","@value":"9000363399474"},{"@type":"NRID","@value":"9000363399571"},{"@type":"NRID","@value":"9000258742855"},{"@type":"NRID","@value":"9000363399543"},{"@type":"NRID","@value":"9000363399588"},{"@type":"NRID","@value":"9000021810533"},{"@type":"NRID","@value":"9000409026211"},{"@type":"NRID","@value":"9000363399545"},{"@type":"NRID","@value":"9000257946522"},{"@type":"NRID","@value":"9000018723797"},{"@type":"NRID","@value":"9000405671257"},{"@type":"NRID","@value":"9000363399613"},{"@type":"NRID","@value":"9000363399620"},{"@type":"NRID","@value":"9000409026227"},{"@type":"NRID","@value":"9000363399547"},{"@type":"NRID","@value":"9000363399508"},{"@type":"NRID","@value":"9000363399598"},{"@type":"NRID","@value":"9000255723722"},{"@type":"NRID","@value":"9000363399551"},{"@type":"NRID","@value":"9000363399549"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0057385"}],"foaf:name":[{"@language":"en","@value":"Kawanishi Masanobu"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Environmental Genetics Laboratory, Frontier Science Innovation Center, Osaka Prefecture University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001205257209858","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000006252422"},{"@type":"NRID","@value":"9000257967104"}],"foaf:name":[{"@language":"en","@value":"Sakamoto Michiyo"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Environmental Genetics Laboratory, Frontier Science Innovation Center, Osaka Prefecture University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001205257209857","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000006252425"},{"@type":"NRID","@value":"9000257967105"}],"foaf:name":[{"@language":"en","@value":"Shimohara Chiaki"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Environmental Genetics Laboratory, Frontier Science Innovation Center, Osaka Prefecture University"}]},{"@id":"https://cir.nii.ac.jp/crid/1420282801201325184","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"80182301"},{"@type":"NRID","@value":"1000080182301"},{"@type":"CINII_AUTHOR_ID","@value":"DA13635366"},{"@type":"URI","@value":"https://ci.nii.ac.jp/author/DA13635366#entity"},{"@type":"URI","@value":"https://viaf.org/viaf/NII%7CDA13635366"},{"@type":"NRID","@value":"9000006252427"},{"@type":"NRID","@value":"9000364822090"},{"@type":"NRID","@value":"9000364818391"},{"@type":"NRID","@value":"9000254247507"},{"@type":"NRID","@value":"9000257967106"},{"@type":"NRID","@value":"9000009824189"},{"@type":"NRID","@value":"9000006939402"},{"@type":"NRID","@value":"9000364746701"},{"@type":"NRID","@value":"9000258742861"},{"@type":"NRID","@value":"9000006939416"},{"@type":"NRID","@value":"9000257946520"},{"@type":"NRID","@value":"9000006799163"},{"@type":"NRID","@value":"9000016860948"},{"@type":"NRID","@value":"9000255723725"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0012317"}],"foaf:name":[{"@language":"en","@value":"Yagi Takashi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Environmental Genetics Laboratory, Frontier Science Innovation Center, Osaka Prefecture University"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"18807046"},{"@type":"EISSN","@value":"18807062"},{"@type":"NDL_BIB_ID","@value":"000007994889"},{"@type":"ISSN","@value":"18807046"},{"@type":"LISSN","@value":"18807046"},{"@type":"NCID","@value":"AA1212552X"}],"prism:publicationName":[{"@language":"en","@value":"Genes and Environment"},{"@language":"en","@value":"Genes and Environment"}],"dc:publisher":[{"@language":"en","@value":"The Japanese Environmental Mutagen and Genome Society"},{"@language":"ja","@value":"日本環境変異原ゲノム学会"}],"prism:publicationDate":"2006","prism:volume":"28","prism:number":"4","prism:startingPage":"167","prism:endingPage":"172"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"http://id.ndl.go.jp/bib/8684370"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I8684370"},{"@id":"https://search.jamas.or.jp/link/ui/2007190225"}],"availableAt":"2006","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=aryl%20hydrocarbon%20receptor","dc:title":"aryl hydrocarbon receptor"},{"@id":"https://cir.nii.ac.jp/all?q=reporter%20yeast","dc:title":"reporter yeast"},{"@id":"https://cir.nii.ac.jp/all?q=species%20specificity","dc:title":"species specificity"},{"@id":"https://cir.nii.ac.jp/all?q=guinea%20pig","dc:title":"guinea pig"},{"@id":"https://cir.nii.ac.jp/all?q=syrian%20hamster","dc:title":"syrian hamster"}],"project":[{"@id":"https://cir.nii.ac.jp/crid/1040000781949524224","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"17710047"},{"@type":"JGN","@value":"JP17710047"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17710047/"}],"notation":[{"@language":"ja","@value":"ヒト細胞における大気浮遊粒子由来物質による突然変異の定量的解析と分子機構の解明"}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050001335849297024","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"New reporter gene assays for detecting natural and synthetic molting hormone agonists using yeasts expressing ecdysone receptors of various insects"}]},{"@id":"https://cir.nii.ac.jp/crid/1050023239833531776","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Development of a New Reporter Gene Assay for Detecting Juvenile Hormone Agonists Using Yeast Expressing Methoprene-Tolerant of the Freshwater Cladoceran Daphnia magna"},{"@value":"Development of a New Reporter Gene Assay for Detecting Juvenile Hormone Agonists Using Yeast Expressing Methoprene‐Tolerant of the Freshwater Cladoceran <scp><i>Daphnia magna</i></scp>"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004232548428800","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Construction of sensitive reporter assay yeasts for comprehensive detection of ligand activities of human corticosteroid receptors through inactivation of CWP and PDR genes"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292618978960768","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Construction of reporter yeasts for mouse aryl hydrocarbon receptor ligand activity"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292620464725376","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A Human Aryl Hydrocarbon Receptor Signaling Pathway Constructed in Yeast Displays Additive Responses to Ligand Mixtures"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294643778257408","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Detection of juvenile hormone agonists by a new reporter gene assay using yeast expressing <i>Drosophila</i> methoprene‐tolerant"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574093689042816","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Transformation of the aryl hydrocarbon receptor to a DNA-binding form is accompanied by release of the 90 kDa heat-shock protein and increased affinity for 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574096371506048","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The AH Receptor of the Most Dioxin-Sensitive Species, Guinea Pig, Is Highly Homologous to the Human AH Receptor"}]},{"@id":"https://cir.nii.ac.jp/crid/1360584339749251200","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Development of a yeast reporter gene assay to detect ligands of freshwater cladoceran <scp><i>Daphnia magna</i></scp> ultraspiracle, a homolog of vertebrate retinoid X receptors"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855570873148928","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Aryl Hydrocarbon Receptor Activation in Genital Tubercle, Palate, and Other Embryonic Tissues in 2,3,7,8-Tetrachlorodibenzo-p-Dioxin-ResponsivelacZMice"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137044297166208","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Specific protein-DNA interactions at a xenobiotic-responsive element: copurification of dioxin receptor and DNA-binding activity."}]},{"@id":"https://cir.nii.ac.jp/crid/1361137045516753792","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors."}]},{"@id":"https://cir.nii.ac.jp/crid/1361418520606127232","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Species-Specific Recombinant Cell Lines as Bioassay Systems for the Detection of 2,3,7,8-Tetrachlorodibenzo-p-dioxin-like Chemicals"}]},{"@id":"https://cir.nii.ac.jp/crid/1361418520793712000","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleus."}]},{"@id":"https://cir.nii.ac.jp/crid/1361699993976167168","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Identification of Functional Domains of the Aryl Hydrocarbon Receptor"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699994577643520","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Expression of the Human Aryl Hydrocarbon Receptor Complex in Yeast"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981469033411328","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Identification of a New Mutagenic Polychlorinated Biphenyl Derivative in the Waka River, Wakayama, Japan, Showing Activation of an Aryl Hydrocarbon Receptor-Dependent Transcription"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981469161795200","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Regulation of Subcellular Localization of the Aryl Hydrocarbon Receptor (AhR)"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981470785164544","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"2,3,7,8-Tetrachlorodibenzo-<i>p</i>-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262944792967936","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Molecular biology of the aromatic hydrocarbon (dioxin) receptor"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262946171782784","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Assessment of aryl hydrocarbon receptor complex interactions using pBEVY plasmids: expressionvectors with bi-directional promoters for use in Saccharomyces cerevisiae"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825893527006848","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Indirubin and Indigo Are Potent Aryl Hydrocarbon Receptor Ligands Present in Human Urine"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825893924672768","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Restructured Transactivation Domain in Hamster AH Receptor"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388843379167616","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A factor binding to the xenobiotic responsive element (XRE) of P-4501A1 gene consists of at least two helix-loop-helix proteins, Ah receptor and Arnt."}]},{"@id":"https://cir.nii.ac.jp/crid/1363388844099526784","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ligand-dependent recruitment of the Arnt coregulator determines DNA recognition by the dioxin receptor."}]},{"@id":"https://cir.nii.ac.jp/crid/1363388844541238272","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Characterization of xenobiotic responsive elements upstream from the drug-metabolizing cytochrome P-450c gene: a similarity to glucocorticoid regulatory elements"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388845586729088","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Identification of the Ah Receptor Nuclear Translocator Protein (Arnt) as a Component of the DNA Binding Form of the Ah Receptor"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670318349177600","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Potent transactivation domains of the Ah receptor and the Ah receptor nuclear translocator map to their carboxyl termini."}]},{"@id":"https://cir.nii.ac.jp/crid/1363670320896251520","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Cloning of a Factor Required for Activity of the Ah (Dioxin) Receptor"}]},{"@id":"https://cir.nii.ac.jp/crid/1570291226768946560","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals"}]},{"@id":"https://cir.nii.ac.jp/crid/1570291226770942720","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A human aryl hydrocarbon receptor signaling pathway constructed in yeast displays additive responses to ligand mixtures"}]},{"@id":"https://cir.nii.ac.jp/crid/1570854176683105280","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Cloning of a factor required for activity of the Ah (dioxin) receptor"}]},{"@id":"https://cir.nii.ac.jp/crid/1571135650498708480","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"The Q-rich subdomain of the human Ah receptor transactivation domain is required for trnacriptional activation of dioxin-responsive gene"}]},{"@id":"https://cir.nii.ac.jp/crid/1571417126679475072","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"The aryl hydrocarbon receptor Studies using the Ahr-null mice"},{"@value":"The aryl hydrocarbon receptor: studies using the AHR‐null mice"}]},{"@id":"https://cir.nii.ac.jp/crid/1571698601620663168","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors"}]},{"@id":"https://cir.nii.ac.jp/crid/1571980075428842112","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Molecular biology of the aromatic hydrocarbon (dioxin) receptor"}]},{"@id":"https://cir.nii.ac.jp/crid/1571980076574079360","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm : its possible translocation to nucleus"}]},{"@id":"https://cir.nii.ac.jp/crid/1571980076599024256","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Physicochemical and immunocytochemical analysis of the aryl hydrocarbon receptor nuclear translocator : characterization of two monoclonal antibodies to the aryl hydrocarbon receptor nuclear translocator"}]},{"@id":"https://cir.nii.ac.jp/crid/1571980076635152000","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Expression of the human aryl hydrocarbon receptor complex in yeast. Activation of transcription by indole compounds"}]},{"@id":"https://cir.nii.ac.jp/crid/1571980076674488960","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Construction of reporter yeasts for mouse aryl hydrocarbon receptor ligand activity"}]},{"@id":"https://cir.nii.ac.jp/crid/1572261550405551616","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Identification of a new mutagenic polychlorinated biphenyl derivative in the Waka River, Wakayama, Japan, showing activation of an aryl hydrocarbon receptor-dependent transcription"}]},{"@id":"https://cir.nii.ac.jp/crid/1572261551575231232","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Ligand-dependent recruitment of the Arnt coregulator determines DNA recognition by the dioxin receptor"}]},{"@id":"https://cir.nii.ac.jp/crid/1572543026573458304","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Short-term toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals : effects, mechanisms, and animal models"}]},{"@id":"https://cir.nii.ac.jp/crid/1572824501558557056","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Potent transactivation domains of the Ah receptor and the Ah receptor nuclear translocator map to their carboxyl termini"}]},{"@id":"https://cir.nii.ac.jp/crid/1573105976480135424","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Specific protein-DNA interactions at a xenobiotic-responsive element : copurification of dioxin receptor and DNA-binding activity"}]},{"@id":"https://cir.nii.ac.jp/crid/1573387449856709632","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"The AH receptor of the most dioxin-sensitive species, guinea pig, is highly homologous to the human AH receptor"}]},{"@id":"https://cir.nii.ac.jp/crid/1573387451480800512","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Transformation of the aryl hydrocarbon receptor to a DNA-binding form is accompanied by release of the 90kDa heat-shock protein and increased affinity for 2,3,7,8-tetrachlorodibenzo-p-dioxin"}]},{"@id":"https://cir.nii.ac.jp/crid/1573387451483761408","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A factor binding to the xenobiotic responsive element (XRE) of P-4501A1 gene consists of at least two helix-loop-helix proteins, Ah receptor and Arnt"}]},{"@id":"https://cir.nii.ac.jp/crid/1573668926484222080","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Identification of functional domains of the aryl hydrocarbon receptor"}]},{"@id":"https://cir.nii.ac.jp/crid/1573668926498344576","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Assessment of aryl hydrocarbon receptor complex interactions using pBEVY plasmids : expressionvectors with bi-directional promoters for use in Saccharomyces cerevisiae"}]},{"@id":"https://cir.nii.ac.jp/crid/1573668926500469760","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Aryl hydrocarbon receptor activation in genital tubercle, palate, and other embryonic tissues in 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive lacZ 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