Current situation of gastric cancer risk evaluation system “ABC classification” in Japanese local governments

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  • 「胃がんリスク評価のABC分類」導入自治体の現状調査
  • 「 イガン リスク ヒョウカ ノ ABC ブンルイ 」 ドウニュウ ジチタイ ノ ゲンジョウ チョウサ

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Abstract

We conducted a questionnaire survey on local governments that introduced the “ABC classification” to evaluate the gastric cancer risk. The investigation items included the timing of introduction, relations with the conventional gastric cancer screening using image examination, cut-off level of pepsinogen (PG) I, the PGI/PGII ratio and Helicobacter pylori (HP) antibody. Additionally, the detection rate of gastric cancer before and after introduction was also surveyed. The number of local governments that introduced this classification increased dramatically after 2011. Most local governments separated the “ABC classification” from conventional gastric cancer screening, but some performed the classification as a substitution for gastric cancer screening. The most used cut off level of PGI,PGI/PGII ratio and HP antibody were <=70ng/ml, <=3, and <10U/ml, respectively. However, the cut off value of <=4 in PGI/PGII ratio was used in some cases. Excluding local governments that detected no gastric cancer, the gastric cancer detection rate before and after introduction was an average of 0.20% and 0.31%. The operation systems of this classification differed among local governments, and central analysis with monitoring is required to establish evidence indicating effectiveness.

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