イヌの動的栄養指標蛋白としての血漿トランスフェリン値の有用性

  • 竹内 由則
    東京大学大学院医学系研究科公共健康医学生物統計学研究室
  • 中島 亘
    東京大学大学院農学生命科学研究科獣医内科学研究室
  • Fujino Y.
    東京大学大学院農学生命科学研究科獣医内科学研究室
  • 辻本 元
    東京大学大学院農学生命科学研究科獣医内科学研究室
  • 竹内 文乃
    東京大学大学院医学系研究科公共健康医学生物統計学研究室
  • 中嶋 眞弓
    東京大学大学院農学生命科学研究科獣医内科学研究室
  • 大野 耕一
    東京大学大学院農学生命科学研究科獣医内科学研究室

書誌事項

タイトル別名
  • Usefulness of plasma transferrin levels as dynamic assessment of protein nutrition in dog
公開日
2012
DOI
  • 10.11266/jpan.15.65
公開者
日本ペット栄養学会

この論文をさがす

説明

Measurement of plasma rapid turnover proteins (RTPs) such as transferrin (Tf) and retinol-binding protein (RBP) have been used as dynamic assessment of protein nutrition in human medicine. The purpose of the present study is to evaluate the clinical usefulness of plasma Tf and RBP levels as a nutritional marker in dogs. We performed the shortterm controlled feeding tests with changing the total calorie in healthy dogs. Plasma Tf levels were significantly decreased during the calorie reduction period, then moderately increased during the calorie re-increased period. In contrast, RBP and albumin (ALB) levels showed no significant change throughout the test. Furthermore, Tf levels were significantly decreased in anorexic (<50% RER, over the last week) dogs with chronic gastrointestinal (GI) diseases compared with no-anorexic (≥50% RER) patients. Tf levels were also serially monitored in two GI patients during aggressive (perenteral and/or enteral feeding) nutritional therapy. As the result, the dog with continuously increased Tf levels recovered but another patient with decreased Tf levels died during hospitalization. Taken together, the serial measurement of plasma Tf levels may be useful to evaluate short-term nutritional status in dogs.

収録刊行物

詳細情報 詳細情報について

  • CRID
    1390001205290418816
  • NII論文ID
    130004565664
  • DOI
    10.11266/jpan.15.65
  • ISSN
    21857601
    13443763
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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