9 微生物の生産する昆虫のキチナーゼ阻害物質allosamidin類の構造

書誌事項

タイトル別名
  • 9 Structures of Allosamidins, Novel Insect Chitinase Inhibitors, Produced by Microorganisms

説明

Allosamidin(1), a novel insect chitinase inhibitor, was isolated from the mycelium of Streptomyces sp. Allosamidin showed strong inhibitory activity against the chitinases of the silkworm, Bombyx mori, in vitro, and also prevented its larval ecdysis in vivo. The structure of allosamidin was elucidated as 1 by acid hydrolysis experiments and analysis of 2D-NMR spectra. 1 is a basic pseudotrisaccharide consisting of N-acetyl-D-allosamine and a novel aminocyclitol derivative(3), termed allosamizoline. Methylallosamidin(2) was isolated from the mycelium of the unidentified actinomycetes and characterized as 2 by spectral comparison with 1.

収録刊行物

詳細情報 詳細情報について

  • CRID
    1390001206073243392
  • NII論文ID
    110006678539
  • DOI
    10.24496/tennenyuki.28.0_65
  • ISSN
    24331856
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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