Five cases of drug-induced liver injury caused by tranilast
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- JIMBO Rika
- Department of Gastroenterology, Showa General Hospital
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- YOSHIOKA Atsushi
- Department of Gastroenterology, Showa General Hospital
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- TAKAHASHI Yuka
- Department of Gastroenterology, Showa General Hospital
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- ONO Keiichi
- Department of Gastroenterology, Showa General Hospital
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- ADACHI Yousuke
- Department of Gastroenterology, Showa General Hospital
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- KOJIMA Shigeru
- Department of Gastroenterology, Showa General Hospital
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- TAKEDA Yuuichi
- Department of Gastroenterology, Showa General Hospital
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- NOUCHI Toshihiko
- Department of Gastroenterology, Showa General Hospital
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- SHIMIZU Seiichiro
- Department of Pathology, Showa General Hospital
Bibliographic Information
- Other Title
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- トラニラストが原因と考えられた薬物性肝障害の5症例
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Description
最近12カ月間にトラニラストが原因と考えられた重症肝障害の5症例を経験した．トラニラスト内服開始後，平均34日目に黄疸を認めて入院となり，内服中止後平均37日で肝機能の正常化を認めた．薬物リンパ球刺激試験は3例に施行したがいずれも陰性で，薬物性肝障害の診断には国際コンセンサス会議の診断基準が有用であった．トラニラストによる肝障害はまれではなく，内服中は定期的に肝機能を検査する必要がある．<br>
Journal
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- Nippon Shokakibyo Gakkai Zasshi
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Nippon Shokakibyo Gakkai Zasshi 102 (8), 1051-1054, 2005
The Japanese Society of Gastroenterology
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Details 詳細情報について
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- CRID
- 1390001206400894720
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- NII Article ID
- 10016860898
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- NII Book ID
- AN00192124
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- COI
- 1:STN:280:DC%2BD2MvlslChsA%3D%3D
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- ISSN
- 13497693
- 04466586
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- PubMed
- 16124713
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- Text Lang
- ja
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- Data Source
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- JaLC
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed