{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390001206427243392.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1292/jvms.62.421"}},{"identifier":{"@type":"COI","@value":"1:CAS:528:DC%2BD3cXjvVWhtrk%3D"}},{"identifier":{"@type":"PMID","@value":"10823730"}},{"identifier":{"@type":"NDL_BIB_ID","@value":"5369478"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/bib/5369478"}},{"identifier":{"@type":"URI","@value":"https://ndlsearch.ndl.go.jp/books/R000000004-I5369478"}},{"identifier":{"@type":"URI","@value":"http://www.jstage.jst.go.jp/article/jvms/62/4/62_4_421/_pdf"}},{"identifier":{"@type":"NAID","@value":"110003920335"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2000199154"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@language":"en","@value":"The Risk of Contrast Media-Induced Ventricular Fibrillation is Low in Canine Coronary Arteriography with Ioxilan."},{"@language":"ja-Kana","@value":"risk of contrast media induced ventricular fibrillation is low in canine coronary arteriography with ioxilan"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"Previous studies have proposed that sodium supplement to nonionic contrast media (CM) can decrease the risk of ventricular fibrillation (VF). This study was designed to compare the occurence of VF induced by ioxilan (containing 9 mmol/LNa<sup>+</sup>) with other nonionic CMs. After wedging a catheter in the right coronary artery, test solutions including ioxilan, ioversol, iomeprol, and iopromide were infused for 30 sec at the rate of 0.4 ml/sec or until VF occurred. Then, incidence of VF, contact time (i.e. the time required to produce VF), and QTc were measured. Also, the CMs other than ioxilan were investigated at sodium levels adjusted to 9 and 20 mmol/L Na<sup>+</sup>. The incidence of VF with ioxilan (0% ) was the lowest of all. In the other CMs, the incidence decreased in accordance with increase of sodium. Iomeprol and iopromide showed significant reduction of VF incidence at the sodium level of 20 mmol/L. The higher sodium supplements also prolonged the contact times. The increase of QTc was the greatest in ioxilan. Ioxilan has the least arrythmogenic property among the current low-osmolality nonionic CMs. This property might be attributable to an optimal sodium concentration of 9 mmol/L in the CM."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410001206427243396","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000003886682"}],"foaf:name":[{"@language":"en","@value":"MISUMI Kazuhiro"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Veterinary Medicine, Kagoshima University, 21-24 Korimoto 1-chome, Kagoshima 890-0065, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001206427243395","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000005641762"}],"foaf:name":[{"@language":"en","@value":"TATENO Oki"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Veterinary Medicine, Kagoshima University, 21-24 Korimoto 1-chome, Kagoshima 890-0065, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001206427243393","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000005513386"}],"foaf:name":[{"@language":"en","@value":"FUJIKI Makoto"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Veterinary Medicine, Kagoshima University, 21-24 Korimoto 1-chome, Kagoshima 890-0065, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1420845751155253120","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"80508036"},{"@type":"NRID","@value":"1000080508036"},{"@type":"NRID","@value":"9000003886688"},{"@type":"NRID","@value":"9000021953665"},{"@type":"NRID","@value":"9000021954086"},{"@type":"NRID","@value":"9000409492463"},{"@type":"NRID","@value":"9000254982327"},{"@type":"NRID","@value":"9000329014557"},{"@type":"NRID","@value":"9000254428818"},{"@type":"NRID","@value":"9000345321004"},{"@type":"NRID","@value":"9000257812022"},{"@type":"NRID","@value":"9000361240372"},{"@type":"NRID","@value":"9000321625205"},{"@type":"NRID","@value":"9000307258189"},{"@type":"NRID","@value":"9000402436596"},{"@type":"NRID","@value":"9000369747484"},{"@type":"NRID","@value":"9000240042241"},{"@type":"NRID","@value":"9000021951760"},{"@type":"NRID","@value":"9000240041883"},{"@type":"NRID","@value":"9000412213705"},{"@type":"NRID","@value":"9000020922541"},{"@type":"NRID","@value":"9000242072692"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/omusubi"}],"foaf:name":[{"@language":"en","@value":"MIURA Naoki"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Veterinary Medicine, Kagoshima University, 21-24 Korimoto 1-chome, Kagoshima 890-0065, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001206427243394","@type":"Researcher","foaf:name":[{"@language":"en","@value":"SAKAMOTO Hiroshi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Veterinary Medicine, Kagoshima University, 21-24 Korimoto 1-chome, Kagoshima 890-0065, Japan"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"09167250"},{"@type":"LISSN","@value":"09167250"},{"@type":"EISSN","@value":"13477439"},{"@type":"NDL_BIB_ID","@value":"000000076864"},{"@type":"ISSN","@value":"09167250"},{"@type":"NCID","@value":"AA10796138"}],"prism:publicationName":[{"@language":"en","@value":"Journal of Veterinary Medical Science"},{"@language":"ja","@value":"Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ"},{"@language":"en","@value":"J. Vet. Med. Sci."},{"@language":"en","@value":"The Journal of Veterinary Medical Science"},{"@language":"ja","@value":"Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｖｅｔｅｒｉｎａｒｙ　Ｍｅｄｉｃａｌ　Ｓｃｉｅｎｃｅ"}],"dc:publisher":[{"@language":"en","@value":"JAPANESE SOCIETY OF VETERINARY SCIENCE"},{"@language":"ja","@value":"公益社団法人 日本獣医学会"}],"prism:publicationDate":"2000","prism:volume":"62","prism:number":"4","prism:startingPage":"421","prism:endingPage":"426"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"http://id.ndl.go.jp/bib/5369478"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I5369478"},{"@id":"http://www.jstage.jst.go.jp/article/jvms/62/4/62_4_421/_pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2000199154"}],"availableAt":"2000","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=contrast%20media","dc:title":"contrast media"},{"@id":"https://cir.nii.ac.jp/all?q=coronary%20arteriography","dc:title":"coronary arteriography"},{"@id":"https://cir.nii.ac.jp/all?q=ioxilan","dc:title":"ioxilan"},{"@id":"https://cir.nii.ac.jp/all?q=ventricular%20fibrillation","dc:title":"ventricular fibrillation"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360011144503015040","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Contrast Media-Induced Ventricular Fibrillation"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619852732800","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Canine Model of Contrast Medium Induced Fibrillation"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292620624950400","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Effect of Sodium on the Fibrillatory Potential of Ioversol"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292620669336192","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"In vivo effects of acute changes in osmolality and 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Theory"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699993405041024","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Sodium Addition and/or Oxygen Saturation of Iohexol during Normal and Reduced Perfusion Pressure"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699994969622144","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Importance of Sodium Concentration on the Incidence of Fibrillation During Coronary Arteriography in Dogs"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699996165826432","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Sodium—Calcium Balance in Nonionic Contrast Media Effects on the Risk of Ventricular Fibrillation in the Isolated Rabbit Heart"}]},{"@id":"https://cir.nii.ac.jp/crid/1361699996348032256","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Reducing the Risk of Ventricular Fibrillation by Adding Sodium to Ionic and Non-Ionic Contrast Media with Low Iodine Concentration"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981469431615616","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ventricular fibrillation in coronary angiography: what is the role of contrast medium?"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981470507056896","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Effect of Sodium Addition to Non-Ionic Contrast Media on Cardiac Contractile Force"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981470543641600","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"ECG Changes and Arrhythmias Induced By Ionic and Non-Ionic Contrast Media During Coronary Arteriography in Dogs"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981470976944384","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"The Effect of Sodium on the Fibrillatory Propensity of Nonionic Contrast Media"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262946424759040","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Cardiac Effects of Adding Electrolytes and Oxygen to Iohexol in a Dog Model of Contrast Media-Induced Ventricular Fibrillation"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544418385046912","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Mechanism of Production of Cardiac Conduction Abnormalities Due to Coronary Arteriography in Dogs"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544419460529664","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Low-Osmolality Contrast Media-Induced Ventricular Fibrillation"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544421093093632","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Slow Response Induced in Canine Purkinje Fiber By Contrast Medium"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388844557789440","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Effects of Contrast Media on the Conducting System of the Heart"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388845420640000","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Ventricular fibrillation during coronary angiography: Reduced incidence with nonionic contrast media"}]},{"@id":"https://cir.nii.ac.jp/crid/1363670319020386176","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Ventricular Fibrillation During Right Coronary Arteriography with Ioxaglate, Iohexol and Iopamidol in Dogs"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233271172571648","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Safety of the nonionic contrast medium omnipaque in coronary angiography"}]},{"@id":"https://cir.nii.ac.jp/crid/1570009749550228736","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Ventricular fibrillation in coronary angiography: what is the role of contrast medium?"}]},{"@id":"https://cir.nii.ac.jp/crid/1570009751556152576","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"ECG changes and arrhythmias induced by ionic and non-ionic contrast media during coronary arteriography in dogs."}]},{"@id":"https://cir.nii.ac.jp/crid/1570291224526889216","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Canine model of contrast medium induced fibrillation."}]},{"@id":"https://cir.nii.ac.jp/crid/1571417124433736192","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Cardiac effects of adding electrolytes and oxygen to iohexol in a dog model of contrast media-induced ventricular fibrillation."}]},{"@id":"https://cir.nii.ac.jp/crid/1571417124433782400","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Sodium addition and/or oxygen saturation of iohexol during normal and reduced perfusion pressure. Effects on contractile force and risk of ventricular fibrillation in the isolated rabbit heart."}]},{"@id":"https://cir.nii.ac.jp/crid/1571698599410444928","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Contrast media induced ventricular fibrillation during coronary angiography in dogs."}]},{"@id":"https://cir.nii.ac.jp/crid/1571698599410447360","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Life-threateing arrhythmias stopped by cough."}]},{"@id":"https://cir.nii.ac.jp/crid/1571698599410492672","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Reducing the risk of ventricular fibrillation by adding sodium to ionic and non-ionic contrast media with low iodine concentration. Coronary perfusion of the isolated rabbit heart with meglumine diatrizoate or iopentol at 140 mgI/ml and 0-154 mmol Na+/l."}]},{"@id":"https://cir.nii.ac.jp/crid/1571980074387154560","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"The effects of ioxilan, a new nonionic contrast medium, on cardiovascular system."}]},{"@id":"https://cir.nii.ac.jp/crid/1571980075578882176","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"The effect of sodium on the fibrillatory potential of ioversol."}]},{"@id":"https://cir.nii.ac.jp/crid/1572261550555620736","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"The need for improved contrast media ioxilan: updating design theory."}]},{"@id":"https://cir.nii.ac.jp/crid/1572824499317287680","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Electrolyte addition to nonionic contrast media. Cardiac effects during experimental coronary arteriography."}]},{"@id":"https://cir.nii.ac.jp/crid/1573105974294048768","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Effect of sodium addition to non-ionic contrast media on cardiac contractile force. 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