The genetic organization of the capsular polysaccharide biosynthesis region of <i>Actinobacillus pleuropneumoniae</i> serotype 15

DOI DOI Web Site Web Site PubMed View 1 Remaining Hide 3 Citations 31 References Open Access
  • ITO Hiroya
    National Institute of Animal Health, National Agriculture and Food Research Organization, 3–1–5 Kannondai, Tsukuba, Ibaraki 305-0856, Japan
  • SUEYOSHI Masuo
    Center for Animal Disease Control, University of Miyazaki, 1–1 Gakuen-Kibanadai, Miyazaki 889-2192, Japan

Bibliographic Information

Other Title
  • Bacteriology : The genetic organization of the capsular polysaccharide biosynthesis region of Actinobacillus pleuropneumoniae serotype 14
  • The genetic organization of the capsular polysaccharide biosynthesis region of Actinobacillus pleuropneumoniae serotype 15
  • The genetic organization of the capsular polysaccharide biosynthesis region of <i>Actinobacillus pleuropneumoniae</i> serotype 14

Search this article

Description

Nucleotide sequence determination and analysis of the cps gene involved in the capsular polysaccharide biosynthesis of Actinobacillus pleuropneumoniae serotype 15 revealed the presence of three open reading frames, designated as cps15ABC genes. At the protein level, Cps15A and Cps15B showed considerably high homology to CpsA (67.0 to 68.7%) and CpsB (31.7 to 36.8%), respectively, of A. pleuropneumoniae serotypes 1, 4 and 12, revealing the common genetic organization of the cps among serotypes 1, 4, 12 and 15. However, Cps15C showed no homology to any proteins of A. pleuropneumoniae serotypes, indicating that cps15C may be specific to serotype 15. This study will provide the basic molecular knowledge necessary for the development of diagnostics and a vaccine for A. pleuropneumoniae serotype 15.

Journal

Citations (3)*help

See more

References(31)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top