Comparison of Molecular and Growth Properties for Two Different Canine Distemper Virus Clusters, Asia 1 and 2, in Japan
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- LAN Nguyen Thi
- Department of Veterinary Pathology, Faculty of Agriculture, University of Miyazaki
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- YAMAGUCHI Ryoji
- Department of Veterinary Pathology, Faculty of Agriculture, University of Miyazaki
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- KAWABATA Atsushi
- Department of Veterinary Pathology, Faculty of Agriculture, University of Miyazaki
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- UCHIDA Kazuyuki
- Department of Veterinary Pathology, Faculty of Agriculture, University of Miyazaki
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- SUGANO Sumio
- The Institute of Medical Science, The University of Tokyo
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- TATEYAMA Susumu
- Department of Veterinary Pathology, Faculty of Agriculture, University of Miyazaki
Bibliographic Information
- Other Title
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- 日本におけるアジア1型及び2型,異なるジステンパーウイルス2群の分子及び増殖性状の比較
- 日本におけるアジア1型及び2型,異なるジステンバーウイルス2群の分子及び増殖性状の比較(ウイルス学)
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Description
To compare the molecular and growth properties of two newly isolated canine distemper virus strains in the Asia 1 and 2 groups with clinico-pathological findings in dogs, nucleotide and predicted amino acid sequence comparisons of genes H and P were performed together with comparative growth profiling. The predicted amino acid sequences of the H gene contained 12 cysteine residues that were conserved among the examined Asia 1 and Asia 2 viruses. The hydrophobic region in the H gene of the Asia 2 isolates was one amino acid longer than that of the Asia 1 group. The H gene of the Asia 1 group had nine putative asparagine (N)-linked glycosylation sites, while there were eight sites in the Asia 2 group. The titers of the cell-associated viruses for the Asia 1 strains were higher than those of the released viruses and were opposite to those of the Asia 2 strains in a previous study. The molecular and growth properties of the Asia 1 and Asia 2 groups seem to vary, although no significant differences were observed in the clinical signs and pathological findings between the two groups.<br>
Journal
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- Journal of Veterinary Medical Science
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Journal of Veterinary Medical Science 69 (7), 739-744, 2007
JAPANESE SOCIETY OF VETERINARY SCIENCE
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Details 詳細情報について
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- CRID
- 1390001206429616640
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- NII Article ID
- 110006366684
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- NII Book ID
- AA10796138
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- ISSN
- 13477439
- 09167250
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- HANDLE
- 10458/1195
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- NDL BIB ID
- 8897005
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- PubMed
- 17675806
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- JaLC
- IRDB
- NDL Search
- Crossref
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed