Burkitt lymphoma is a high-grade B-cell lymphoma. In children, the symptoms of this disease vary depending on the primary site and include a few systemic symptoms, including fever and weight loss. Malignant lymphoma of the nasal cavity and paranasal sinuses is very rare. Herein, we report two cases of Burkitt lymphoma in the paranasal sinuses in children with rapid onset of visual impairment.
Both cases developed visual impairment and were admitted to the pediatric department and then referred to our department. Computed tomography and magnetic resonance imaging revealed mass lesions in the paranasal sinuses. Biopsies led to diagnosis of Burkitt lymphoma. Chemotherapy was administered and complete remission has been maintained since the end of treatment. However, blindness developed as a complication in case 1. These cases emphasize the need to be aware of the rapid progression of symptoms of Burkitt lymphoma.
"},{"@language":"ja","@value":"バーキットリンパ腫は高悪性度B細胞リンパ腫である。小児では発熱や体重減少などの全身症状を呈することは少なく，原発部位による多彩な症状が出現するが，これらの症状を契機に病院受診されることが多い。鼻副鼻腔を原発とする悪性リンパ腫は非常に稀であるが，今回，急速な視力障害を呈した小児副鼻腔バーキットリンパ腫の2例を経験したので考察を加えてここに報告する。
両症例ともに急速な視力障害の症状を認めた。画像検査にていずれも鼻副鼻腔に腫瘤性病変を認め，生検にてバーキットリンパ腫の診断となった。化学療法を施行し，両症例とも完全寛解の状態であるが，1例では視力の改善が得られなかった。バーキットリンパ腫は急速に進行し，周囲臓器へ浸潤傾向を示すため早期の診断・治療が重要である。
"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410010292825849476","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Hayashi Tatsuya"},{"@language":"ja","@value":"林 達哉"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University"},{"@language":"ja","@value":"旭川医科大学 耳鼻咽喉科・頭頸部外科講座"}]},{"@id":"https://cir.nii.ac.jp/crid/1410010292825849472","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Harabuchi Yasuaki"},{"@language":"ja","@value":"原渕 保明"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"旭川医科大学 耳鼻咽喉科・頭頸部外科講座"},{"@language":"en","@value":"Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410010292825849473","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Kumai Takumi"},{"@language":"ja","@value":"熊井 琢美"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"旭川医科大学 耳鼻咽喉科・頭頸部外科講座"},{"@language":"en","@value":"Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410010292825849475","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Ominato Hisataka"},{"@language":"ja","@value":"大湊 久貴"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University"},{"@language":"ja","@value":"旭川医科大学 耳鼻咽喉科・頭頸部外科講座"}]},{"@id":"https://cir.nii.ac.jp/crid/1410010292825849478","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Takahara Miki"},{"@language":"ja","@value":"高原 幹"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"旭川医科大学 耳鼻咽喉科・頭頸部外科講座"},{"@language":"en","@value":"Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410010292825849479","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Katada Akihiro"},{"@language":"ja","@value":"片田 彰博"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"旭川医科大学 耳鼻咽喉科・頭頸部外科講座"},{"@language":"en","@value":"Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410010292825849477","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Yamaki Hidekiyo"},{"@language":"ja","@value":"山木 英聖"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University"},{"@language":"ja","@value":"旭川医科大学 耳鼻咽喉科・頭頸部外科講座"}]},{"@id":"https://cir.nii.ac.jp/crid/1410010292825849474","@type":"Researcher","foaf:name":[{"@language":"en","@value":"Kishibe Kan"},{"@language":"ja","@value":"岸部 幹"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"旭川医科大学 耳鼻咽喉科・頭頸部外科講座"},{"@language":"en","@value":"Department of Otolaryngology-Head & Neck Surgery, Asahikawa Medical University"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"09195858"},{"@type":"EISSN","@value":"21865957"},{"@type":"NDL_BIB_ID","@value":"000000084420"},{"@type":"ISSN","@value":"09195858"},{"@type":"LISSN","@value":"09195858"}],"prism:publicationName":[{"@language":"en","@value":"Pediatric Otorhinolaryngology Japan"},{"@value":"小児耳鼻咽喉科"},{"@language":"en","@value":"Ped ORL J"},{"@value":"小児耳鼻咽喉科"}],"dc:publisher":[{"@language":"en","@value":"Japan Society for Pediatric Otorhinolaryngology"},{"@language":"ja","@value":"日本小児耳鼻咽喉科学会"}],"prism:publicationDate":"2021","prism:volume":"42","prism:number":"3","prism:startingPage":"342","prism:endingPage":"348"},"url":[{"@id":"http://id.ndl.go.jp/bib/032540742"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I032540742"},{"@id":"https://search.jamas.or.jp/link/ui/2022162005"}],"availableAt":"2021","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=%E3%83%90%E3%83%BC%E3%82%AD%E3%83%83%E3%83%88%E3%83%AA%E3%83%B3%E3%83%91%E8%85%AB","dc:title":"バーキットリンパ腫"},{"@id":"https://cir.nii.ac.jp/all?q=%E8%A6%96%E5%8A%9B%E9%9A%9C%E5%AE%B3","dc:title":"視力障害"},{"@id":"https://cir.nii.ac.jp/all?q=%E5%89%AF%E9%BC%BB%E8%85%94","dc:title":"副鼻腔"},{"@id":"https://cir.nii.ac.jp/all?q=%E5%B0%8F%E5%85%90","dc:title":"小児"},{"@id":"https://cir.nii.ac.jp/all?q=Burkitt%20lymphoma","dc:title":"Burkitt lymphoma"},{"@id":"https://cir.nii.ac.jp/all?q=visual%20impairment","dc:title":"visual impairment"},{"@id":"https://cir.nii.ac.jp/all?q=sinus","dc:title":"sinus"},{"@id":"https://cir.nii.ac.jp/all?q=pediatric","dc:title":"pediatric"}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:2009224251"},{"@type":"NDL_SEARCH","@value":"oai:ndlsearch.ndl.go.jp:R000000004-I032540742"}]}