{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390011108717876096.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.2463/mrms.mp.2020-0151"}},{"identifier":{"@type":"PMID","@value":"33883364"}},{"identifier":{"@type":"URI","@value":"https://www.jstage.jst.go.jp/article/mrms/21/3/21_mp.2020-0151/_pdf"}},{"identifier":{"@type":"NAID","@value":"130008027874"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2024046610"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@language":"en","@value":"Differentiating Liver Hemangioma from Metastatic Tumor Using T2-enhanced Spin-echo Imaging with a Time-reversed Gradient-echo Sequence in the Hepatobiliary Phase of Gadoxetic Acid-enhanced MR Imaging"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"<p>Purpose: To evaluate the utility of T2-enhanced spin-echo imaging using the time-reversed gradient echo sequence (T2FFE imaging) in the hepatobiliary phase (HBP) of gadoxetic acid-enhanced MRI (Gd-EOB-MRI) for differentiating hemangiomas from metastatic tumors.</p><p>Methods: A total of 61 patients with 133 liver lesions, including 37 hemangiomas and 96 metastatic tumors, were scanned by Gd-EOB-MRI. Four data sets were independently analyzed by two readers: (1) 3D fat-suppressed T2-weighted imaging (FS-T2WI) alone; (2) the combination of 3D FS-T2WI and T2FFE imaging in the HBP of Gd-EOB-MRI; (3) the combination of 3D FS-T2WI, diffusion-weighted imaging (DWI) with the b-value of 1000 s/mm<sup>2</sup> and the apparent diffusion coefficient (ADC); and (4) a dynamic study of Gd-EOB-MRI. After classifying the lesion sizes as ≤ 10 mm or > 10 mm, we conducted a receiver-operating characteristic analysis to compare diagnostic accuracies among the four data sets for differentiating hemangiomas from metastatic tumors.</p><p>Results: The areas under the curves (AUCs) of the four data sets of two readers were: (1) ≤ 10 mm (0.85 and 0.91) and > 10 mm (0.88 and 0.97), (2) ≤ 10 mm (0.94 and 0.94) and > 10 mm (0.96 and 0.95), (3) ≤ 10 mm (0.90 and 0.87) and > 10 mm (0.89 and 0.95), and (4) ≤ 10 mm (0.62 and 0.67) and > 10 mm (0.76 and 0.71), respectively. Data sets (2) and (3) showed no significant differences in AUCs, but both showed significantly higher AUCs compared to that of (4) regardless of the lesion size (<i>P</i> < 0.05).</p><p>Conclusion: The combination of 3D FS-T2WI and T2FFE imaging in the HBP of Gd-EOB-MRI achieved an accuracy equivalent to that of the combination of 3D FS-T2WI, DWI, and ADC and might be helpful in differentiating hemangiomas from metastatic tumors.</p>"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410011108717876097","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000412134342"}],"foaf:name":[{"@language":"en","@value":"Takayama Yukihisa"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410011108717876101","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000412134343"}],"foaf:name":[{"@language":"en","@value":"Nishie Akihiro"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410011108717876104","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000412134344"}],"foaf:name":[{"@language":"en","@value":"Okamoto Daisuke"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410011108717876098","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000412134345"}],"foaf:name":[{"@language":"en","@value":"Fujita Nobuhiro"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Clinical Radiology, 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