A case of clear cell cancer of the cervix diagnosed by liquid-based cytology

  • KUBOTA Emi
    Department of Pathology/Pathology Diagnosis, Kagoshima University Hospital
  • KITAZONO Ikumi
    Department of Pathology/Pathology Diagnosis, Kagoshima University Hospital
  • IWAKIRI Kaori
    Department of Pathology/Pathology Diagnosis, Kagoshima University Hospital
  • KIRITA Yukari
    Department of Pathology/Pathology Diagnosis, Kagoshima University Hospital
  • TASAKI Takashi
    Department of Pathology Field, Kagoshima University Graduate School of Medical and Dental Sciences
  • HIGASHI Michiyo
    Department of Pathology/Pathology Diagnosis, Kagoshima University Hospital
  • YANAZUME Shintaro
    Department of Reproductive Pathophysiology (Obstetrics and Gynecology Classroom), Kagoshima University Graduate School of Medical and Dental Sciences
  • KOBAYASHI Hiroaki
    Department of Reproductive Pathophysiology (Obstetrics and Gynecology Classroom), Kagoshima University Graduate School of Medical and Dental Sciences
  • TANIMOTO Akihide
    Department of Pathology/Pathology Diagnosis, Kagoshima University Hospital Department of Pathology Field, Kagoshima University Graduate School of Medical and Dental Sciences

Bibliographic Information

Other Title
  • 液状化検体細胞診で診断した子宮頸部明細胞癌の 1 例
Published
2023
DOI
  • 10.5795/jjscc.62.287
Publisher
The Japanese Society of Clinical Cytology

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Description

<p>Background : Few studies have investigated the usefulness of liquid-based cytology (LBC) specimens in patients with primary clear cell carcinoma of the cervix, a rare neoplasm. Herein, we report the case of a patient who was diagnosed as having primary clear cell carcinoma of the cervix based on LBC, and discuss the differences between LBC and smear cytology, and useful findings for differentiation from other adenocarcinomas.</p><p>Case : The patient was a 70-year-old woman. LBC examination revealed both isolated tumor cells and tumor cells in clusters ; glandular, papillary, and hobnail-like formations were also observed. On LBC, tumor cells with abundant and fine granular cytoplasm, enlarged round nuclei, and large and prominent nucleoli were observed.</p><p>Conclusion : These findings could be helpful in the diagnosis of cervical cell carcinoma using LBC.</p>

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