The assessment of odour and/or smell in indoor environments has basically relied on sensory testing by human volunteers. In recent years, there has been active development of olfactory sensing devices and electronic noses based on semiconductor sensors. On the other hand, the development of a digital twin, which mathematically describes the olfactory mechanism in the human nasal cavity and reproduces it on a computer, is also being researched. This paper presents the current status and future prospects for the development of an in silico nose based on computational fluid dynamics and physiologically based pharmacokinetic models.
"},{"@language":"ja","@value":"室内環境中のにおい・かおりの評価は基本的にボランティア被験者による官能試験に依存してきたが，近年は，半導体センサー（所謂ガスセンサー）を応用した臭気測定器や電子鼻の開発が活発であり，被験者による官能試験を補完する手法としての利用も進んでいる．その一方で，ヒトの鼻腔と嗅覚メカニズムを数理的に記述して計算機上に再現する数値鼻（in silico nose）開発に関する研究も行われている．本稿では，計算流体力学と生理的薬物動態モデルを基盤とした数値鼻の開発動向と今後の展望を紹介する．
"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410019457532471424","@type":"Researcher","foaf:name":[{"@language":"en","@value":"ITO Kazuhide"},{"@language":"ja","@value":"伊藤 一秀"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"九州大学総合理工学研究院環境理工学部門"},{"@language":"en","@value":"Faculty of Engineering Sciences, Kyushu University"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"13482904"},{"@type":"LISSN","@value":"13482904"},{"@type":"EISSN","@value":"13497847"}],"prism:publicationName":[{"@language":"en","@value":"Journal of Japan Association on Odor Environment"},{"@language":"ja","@value":"におい・かおり環境学会誌"},{"@language":"en","@value":"Journal of Japan Association on Odor Environment"},{"@language":"ja","@value":"におい・かおり環境学会誌"}],"dc:publisher":[{"@language":"en","@value":"Japan Association on Odor Environment"},{"@language":"ja","@value":"公益社団法人におい・かおり環境協会"}],"prism:publicationDate":"2024-07-25","prism:volume":"55","prism:number":"4","prism:startingPage":"211","prism:endingPage":"224"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"https://www.jstage.jst.go.jp/article/jao/55/4/55_211/_pdf"}],"availableAt":"2024-07-25","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=In%20silico%20nose","dc:title":"In silico nose"},{"@id":"https://cir.nii.ac.jp/all?q=Computational%20fluid%20dynamics%20(CFD)","dc:title":"Computational fluid dynamics (CFD)"},{"@id":"https://cir.nii.ac.jp/all?q=Odour%20intensity","dc:title":"Odour intensity"},{"@id":"https://cir.nii.ac.jp/all?q=Perceived%20air%20quality","dc:title":"Perceived air quality"},{"@id":"https://cir.nii.ac.jp/all?q=Physiologically-based%20pharmacokinetics%20(PBPK)","dc:title":"Physiologically-based pharmacokinetics (PBPK)"},{"@id":"https://cir.nii.ac.jp/all?q=%E6%95%B0%E5%80%A4%E9%BC%BB","dc:title":"数値鼻"},{"@id":"https://cir.nii.ac.jp/all?q=%E8%A8%88%E7%AE%97%E6%B5%81%E4%BD%93%E5%8A%9B%E5%AD%A6","dc:title":"計算流体力学"},{"@id":"https://cir.nii.ac.jp/all?q=%E8%87%AD%E6%B0%97%E5%BC%B7%E5%BA%A6","dc:title":"臭気強度"},{"@id":"https://cir.nii.ac.jp/all?q=%E7%9F%A5%E8%A6%9A%E7%A9%BA%E6%B0%97%E8%B3%AA","dc:title":"知覚空気質"},{"@id":"https://cir.nii.ac.jp/all?q=%E7%94%9F%E7%90%86%E7%9A%84%E8%96%AC%E7%89%A9%E5%8B%95%E6%85%8B","dc:title":"生理的薬物動態"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360301164101171840","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A pilot numerical study of odorant transport to the olfactory region during sensory evaluations following ISO 16000-28"}]},{"@id":"https://cir.nii.ac.jp/crid/1360582642580700288","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A principal odor map unifies diverse tasks in olfactory perception"}]}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:2013271189"},{"@type":"CROSSREF","@value":"10.2171/jao.55.211"},{"@type":"OPENAIRE","@value":"doi_________::4634b5101b17473756e307953d81498d"}]}