Preliminary experience of initial and re-administration of nimustine as a new primary treatment for feline nasal lymphoma

DOI
  • Goda Yoshimichi
    Graduate School of Medicine and Veterinary Medicine, University of Miyazaki
  • Goto Mifumi
    Myuu Animal Clinic
  • Hidaka Yuichi
    Graduate School of Medicine and Veterinary Medicine, University of Miyazaki Faculty of Agriculture, University of Miyazaki
  • Inoue Yoshiyuki
    Faculty of Agriculture, University of Miyazaki
  • Kuroda Kohei
    Faculty of Agriculture, University of Miyazaki
  • Sato Reiichiro
    Graduate School of Medicine and Veterinary Medicine, University of Miyazaki Faculty of Agriculture, University of Miyazaki
  • Nakatake Yuki
    The Miyazaki University Veterinary Teaching Hospital
  • Satoh Hiroyuki
    Graduate School of Medicine and Veterinary Medicine, University of Miyazaki Faculty of Agriculture, University of Miyazaki

Bibliographic Information

Other Title
  • a case report
Published
2024-10-30
DOI
  • 10.57494/jjvr.72.2_56
Publisher
Japanese Journal of Veterinary Research Editorial Committee

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Description

A 5-year-old spayed female domestic short haired cat presented with chronic nasal obstruction. The cat was diagnosed with B-cell nasal lymphoma based on histological examination of biopsy specimens and intracranial invasion was suspected. We initiated treatment with nimustine (ACNU), known to pass the blood–brain barrier, as the primary protocol with prednisolone, with the owner’s consent. The ACNU dose was 20–25 mg/m² (4–5-week intervals, four or six administrations, two courses). The cat remained oligosymptomatic until day 962 after the first dose and no serious adverse events were reported. The cat lived until day 1089. To our knowledge, this is the first report of long-term survival achieved using ACNU as the primary treatment in a cat with nasal lymphoma.

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Details 詳細情報について

  • CRID
    1390020530236895616
  • DOI
    10.57494/jjvr.72.2_56
  • ISSN
    2758447X
    00471917
  • Text Lang
    en
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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