Felis catus papillomavirus (FcaPV) was first discovered in 2002. Seven genotypes (FcaPV-1/-2/-3/-4/-5/-6/-7) have been reported to date, at least one of which (FcaPV-2) is suggested to be implicated in squamous cell carcinoma (SCC); however, relevant epidemiological data on Japanese cats are limited. There is one report on relatively low FcaPV-2 prevalence in cats with SCC, largely in the Tokyo region. In this study, we investigated the prevalence of each FcaPV genotype in cats with SCC largely drawn from a peripheral region of Japan (Kyushu). Formalin-fixed paraffin-embedded (FFPE) specimens from 107 cats with SCC were subjected to DNA extraction for type-specific PCR assays, followed by confirmatory nucleotide sequencing. Overall, 16 cases (15.0%) were positive for FcaPV, and the results detected for FcaPV-1/-2/-3/-4/-5/-6/-7 were 0/107 (0.0%), 7/107 (6.5%), 4/107 (3.7%), 1/107 (0.9%), 3/107 (2.8%), 1/107 (0.9%), and 1/107 (0.9%), respectively. Our results suggest that FcaPV-2 is the prevalent papillomavirus type in cats with SCC across Japan, but the figure is lower than in other countries. This is also the first report on the detection of FcaPV-6 and FcaPV-7 in Japan, which previously have only been reported in Australia and New Zealand, respectively.
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Vet. Med. Sci."},{"@language":"en","@value":"The Journal of Veterinary Medical Science"},{"@language":"ja","@value":"Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｖｅｔｅｒｉｎａｒｙ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ"}],"dc:publisher":[{"@language":"en","@value":"JAPANESE SOCIETY OF VETERINARY SCIENCE"},{"@language":"ja","@value":"公益社団法人 日本獣医学会"}],"prism:publicationDate":"2025","prism:volume":"87","prism:number":"6","prism:startingPage":"626","prism:endingPage":"633"},"reviewed":"false","url":[{"@id":"https://www.jstage.jst.go.jp/article/jvms/87/6/87_24-0503/_pdf"}],"availableAt":"2025","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=%3Ci%3EFelis%20catus%3C/i%3E%20papillomavirus","dc:title":"Felis catus papillomavirus"},{"@id":"https://cir.nii.ac.jp/all?q=PCR","dc:title":"PCR"},{"@id":"https://cir.nii.ac.jp/all?q=squamous%20cell%20carcinoma","dc:title":"squamous cell carcinoma"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360011146108922880","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Human 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