書誌事項
- タイトル別名
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- X-ray Crystal Structure of the Vault, Largest Ribonucleoprotein Particle, with a Molecular Weight of 10 MDa
- ブンシリョウ ヤク 1000マン ノ キョダイリュウシ vault ノ Xセン ケッショウ コウゾウ カイセキ
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説明
Vaults are among the largest cytoplasmic ribonucleoprotein particles and are found in numerous eukaryotic species. Although roles in multidrug resistance and innate immunity have been suggested, the cellular function remains unclear. We have determined the X-ray structure of rat liver vault at 3.5 Å resolution. A vault particle shell was composed of 78 MVP (Major vault protein) chains with 39-fold dihedral symmetry. The shoulder domain of MVP is structurally similar to SPFH (stomatin/prohibitin/flotillin/HflK/C) domain involved in lipid raft association.
収録刊行物
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- 日本結晶学会誌
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日本結晶学会誌 51 (3), 189-194, 2009
日本結晶学会
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詳細情報 詳細情報について
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- CRID
- 1390282679064596992
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- NII論文ID
- 10025158264
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- NII書誌ID
- AN00188364
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- COI
- 1:CAS:528:DC%2BD1MXot1CnsL8%3D
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- ISSN
- 18845576
- 03694585
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- NDL書誌ID
- 10368748
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可