{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679142439936.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1248/cpb.37.1637"}},{"identifier":{"@type":"URI","@value":"http://www.jstage.jst.go.jp/article/cpb1958/37/6/37_6_1637/_pdf"}},{"identifier":{"@type":"NAID","@value":"130003944761"}}],"dc:title":[{"@language":"en","@value":"Preparation of deuterium-labeled isoniazid for isotope dilution analysis."}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"A method was established for preparation of deuterated isoniazid(<SUP>2</SUP>H-INAH). In this method isonicotinic acid N-oxide was deuterated by base-catalyzed exchange reaction and converted to <SUP>2</SUP>H-INAH. The deuterium content of the <SUP>2</SUP>H-INAH obtained by this method was 95.2 atom%D. This <SUP>2</SUP>H-INAH is suitable for use as an internal standard in gas chromatography-mass spectrometry."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1030285133330316673","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"20035546"},{"@type":"NRID","@value":"1000020035546"},{"@type":"NRID","@value":"9000392643084"},{"@type":"NRID","@value":"9000392648156"},{"@type":"NRID","@value":"9000254704037"},{"@type":"NRID","@value":"9000256475407"},{"@type":"NRID","@value":"9000254700728"},{"@type":"NRID","@value":"9000392639746"},{"@type":"NRID","@value":"9000020354065"}],"foaf:name":[{"@language":"en","@value":"MATSUKI Yoko"},{"@language":"ja","@value":"松木 洋子"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679142439936","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000254700729"}],"foaf:name":[{"@language":"en","@value":"KATAKUSE Yoshimitsu"},{"@language":"ja","@value":"交久瀬 善三"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679142439938","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000254700730"}],"foaf:name":[{"@language":"en","@value":"KATASHIMA Masataka"},{"@language":"ja","@value":"片島 正貴"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679142439937","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000254700731"}],"foaf:name":[{"@language":"en","@value":"MATSUURA Hiroshi"},{"@language":"ja","@value":"松浦 博"}]},{"@id":"https://cir.nii.ac.jp/crid/1030003658343015168","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"80037605"},{"@type":"NRID","@value":"1000080037605"},{"@type":"NRID","@value":"9000392638634"},{"@type":"NRID","@value":"9000397716671"},{"@type":"NRID","@value":"9000021852084"},{"@type":"NRID","@value":"9000254697291"},{"@type":"NRID","@value":"9000392643096"},{"@type":"NRID","@value":"9000392670861"},{"@type":"NRID","@value":"9000254681852"},{"@type":"NRID","@value":"9000397717046"},{"@type":"NRID","@value":"9000378107118"},{"@type":"NRID","@value":"9000380126957"},{"@type":"NRID","@value":"9000254704041"},{"@type":"NRID","@value":"9000256743581"},{"@type":"NRID","@value":"9000018605750"},{"@type":"NRID","@value":"9000254679052"},{"@type":"NRID","@value":"9000254217275"},{"@type":"NRID","@value":"9000256743673"},{"@type":"NRID","@value":"9000255919788"},{"@type":"NRID","@value":"9000020277772"},{"@type":"NRID","@value":"9000392640219"},{"@type":"NRID","@value":"9000254682928"},{"@type":"NRID","@value":"9000397717042"},{"@type":"NRID","@value":"9000397716423"},{"@type":"NRID","@value":"9000378075898"},{"@type":"NRID","@value":"9000397716877"},{"@type":"NRID","@value":"9000020353810"},{"@type":"NRID","@value":"9000256738765"},{"@type":"NRID","@value":"9000397717038"},{"@type":"NRID","@value":"9000254215215"},{"@type":"NRID","@value":"9000397717044"},{"@type":"NRID","@value":"9000256744983"},{"@type":"NRID","@value":"9000256743653"},{"@type":"NRID","@value":"9000256745888"},{"@type":"NRID","@value":"9000254215381"},{"@type":"NRID","@value":"9000254700732"},{"@type":"NRID","@value":"9000256745582"},{"@type":"NRID","@value":"9000256744598"},{"@type":"NRID","@value":"9000254679655"},{"@type":"NRID","@value":"9000397717205"},{"@type":"NRID","@value":"9000397717406"},{"@type":"NRID","@value":"9000020354061"},{"@type":"NRID","@value":"9000254215683"},{"@type":"NRID","@value":"9000397717032"},{"@type":"NRID","@value":"9000380126952"},{"@type":"NRID","@value":"9000254225675"},{"@type":"NRID","@value":"9000254692718"},{"@type":"NRID","@value":"9000255917938"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0036014"}],"foaf:name":[{"@language":"en","@value":"GOROMARU Tsuyoshi"},{"@language":"ja","@value":"五郎丸 毅"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00092363"},{"@type":"EISSN","@value":"13475223"}],"prism:publicationName":[{"@language":"ja","@value":"ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ"},{"@language":"en","@value":"Chemical and Pharmaceutical Bulletin"},{"@language":"en","@value":"Chem. Pharm. Bull."},{"@language":"en","@value":"CHEMICAL & PHARMACEUTICAL BULLETIN"},{"@language":"ja","@value":"Ｃｈｅｍ．　Ｐｈａｒｍ．　Ｂｕｌｌ．"}],"dc:publisher":[{"@language":"en","@value":"The Pharmaceutical Society of Japan"},{"@language":"ja","@value":"公益社団法人 日本薬学会"}],"prism:publicationDate":"1989","prism:volume":"37","prism:number":"6","prism:startingPage":"1637","prism:endingPage":"1638"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"http://www.jstage.jst.go.jp/article/cpb1958/37/6/37_6_1637/_pdf"}],"availableAt":"1989","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=isoniazid","dc:title":"isoniazid"},{"@id":"https://cir.nii.ac.jp/all?q=deuterium%20label","dc:title":"deuterium label"},{"@id":"https://cir.nii.ac.jp/all?q=isotope%20dilution","dc:title":"isotope dilution"},{"@id":"https://cir.nii.ac.jp/all?q=GC-MS","dc:title":"GC-MS"},{"@id":"https://cir.nii.ac.jp/all?q=base-catalyzed%20deuteration","dc:title":"base-catalyzed deuteration"}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:0017409754"},{"@type":"CROSSREF","@value":"10.1248/cpb.37.1637"},{"@type":"CIA","@value":"130003944761"},{"@type":"OPENAIRE","@value":"doi_dedup___::2fd6ddb3972babeef1815c825ca67523"}]}