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It showed 50% inhibition at 1.7 μM compared to 8.1 μM for cyclohexylamine, and 2.5 μM for S-adenosyl-1, 8-diamino-3-thiooctane, known as the most potent inhibitor. The inhibition was competitive with putrescine, similar to cyclohexylamine, and the Ki was 40 nM."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410282679142584064","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000254229665"}],"foaf:name":[{"@language":"en","@value":"Shirahata Akira"},{"@language":"ja","@value":"白幡 晶"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679142584066","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000254229666"}],"foaf:name":[{"@language":"en","@value":"Morohoshi Toru"},{"@language":"ja","@value":"諸星 徹"}]},{"@id":"https://cir.nii.ac.jp/crid/1030003658329788168","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"00072413"},{"@type":"NRID","@value":"1000000072413"},{"@type":"NRID","@value":"9000005217782"},{"@type":"NRID","@value":"9000254670235"},{"@type":"NRID","@value":"9000254229667"},{"@type":"NRID","@value":"9000392662161"},{"@type":"NRID","@value":"9000020978973"},{"@type":"NRID","@value":"9000008477183"},{"@type":"NRID","@value":"9000254684597"},{"@type":"NRID","@value":"9000254211151"},{"@type":"NRID","@value":"9000256285136"},{"@type":"NRID","@value":"9000254680210"},{"@type":"NRID","@value":"9000283435260"},{"@type":"NRID","@value":"9000254239281"},{"@type":"NRID","@value":"9000254683992"},{"@type":"NRID","@value":"9000253245793"},{"@type":"NRID","@value":"9000283564628"},{"@type":"NRID","@value":"9000253245733"},{"@type":"NRID","@value":"9000005245299"},{"@type":"NRID","@value":"9000254226540"},{"@type":"NRID","@value":"9000017870719"},{"@type":"NRID","@value":"9000254670877"},{"@type":"NRID","@value":"9000022202309"},{"@type":"NRID","@value":"9000006567905"},{"@type":"NRID","@value":"9000254673876"},{"@type":"NRID","@value":"9000254218717"},{"@type":"NRID","@value":"9000254208926"},{"@type":"NRID","@value":"9000005215489"},{"@type":"NRID","@value":"9000391627655"},{"@type":"NRID","@value":"9000021872530"},{"@type":"NRID","@value":"9000255783551"},{"@type":"NRID","@value":"9000254674334"},{"@type":"NRID","@value":"9000254208141"},{"@type":"NRID","@value":"9000254216516"},{"@type":"NRID","@value":"9000253245788"},{"@type":"NRID","@value":"9000020799868"},{"@type":"NRID","@value":"9000254224998"},{"@type":"NRID","@value":"9000254705945"},{"@type":"NRID","@value":"9000254222902"},{"@type":"NRID","@value":"9000253245476"},{"@type":"NRID","@value":"9000256285151"},{"@type":"NRID","@value":"9000253205690"},{"@type":"NRID","@value":"9000254214887"},{"@type":"NRID","@value":"9000254701256"},{"@type":"NRID","@value":"9000256284465"},{"@type":"NRID","@value":"9000004505157"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0023288"}],"foaf:name":[{"@language":"en","@value":"Samejima Keijiro"},{"@language":"ja","@value":"鮫島 啓二郎"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00092363"},{"@type":"EISSN","@value":"13475223"}],"prism:publicationName":[{"@language":"ja","@value":"ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ"},{"@language":"en","@value":"Chemical and Pharmaceutical Bulletin"},{"@language":"en","@value":"Chem. Pharm. Bull."},{"@language":"en","@value":"CHEMICAL & PHARMACEUTICAL BULLETIN"},{"@language":"ja","@value":"Ｃｈｅｍ．　Ｐｈａｒｍ．　Ｂｕｌｌ．"}],"dc:publisher":[{"@language":"en","@value":"The Pharmaceutical Society of Japan"},{"@language":"ja","@value":"公益社団法人 日本薬学会"}],"prism:publicationDate":"1988","prism:volume":"36","prism:number":"8","prism:startingPage":"3220","prism:endingPage":"3222"},"reviewed":"false","url":[{"@id":"http://www.jstage.jst.go.jp/article/cpb1958/36/8/36_8_3220/_pdf"}],"availableAt":"1988","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=4-methylcyclohexylamine","dc:title":"4-methylcyclohexylamine"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050001202793503744","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001206126919680","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"ポリアミンの調節と癌"},{"@language":"en","@value":"Regulation of Polyamine and Cancer"},{"@language":"ja-Kana","@value":"ポリアミン ノ チョウセツ ト ガン"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679236452480","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Determination of Cellular Aminopropyltransferase Activity Using Precolumn Fluorescent Etheno-Derivatization with High-Performance Liquid Chromatography"}]}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:0017295679"},{"@type":"CROSSREF","@value":"10.1248/cpb.36.3220"},{"@type":"PUBMED","@value":"3240528"},{"@type":"CIA","@value":"130003771211"},{"@type":"CROSSREF","@value":"10.1007/s00726-011-1037-5_references_DOI_IOiJA422dkf6KTMp3QrGi7kxCGW"},{"@type":"CROSSREF","@value":"10.1248/yakushi.126.529_references_DOI_IOiJA422dkf6KTMp3QrGi7kxCGW"},{"@type":"CROSSREF","@value":"10.2116/analsci.28.621_references_DOI_IOiJA422dkf6KTMp3QrGi7kxCGW"}]}