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This is a continuation of our research involving the design, synthesis, and evaluation of chiral fluorine-containing organic molecules as effective analogues of pharmacologically important compounds."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410001204171295745","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000001638872"}],"foaf:name":[{"@language":"en","@value":"Fujisawa Hidehito"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University"}]},{"@id":"https://cir.nii.ac.jp/crid/1420001326234874624","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"70361962"},{"@type":"NRID","@value":"1000070361962"},{"@type":"NRID","@value":"9000398261724"},{"@type":"NRID","@value":"9000391968364"},{"@type":"NRID","@value":"9000391964517"},{"@type":"NRID","@value":"9000391963245"},{"@type":"NRID","@value":"9000391396939"},{"@type":"NRID","@value":"9000314379996"},{"@type":"NRID","@value":"9000406225973"},{"@type":"NRID","@value":"9000391972670"},{"@type":"NRID","@value":"9000006710599"},{"@type":"NRID","@value":"9000391974443"},{"@type":"NRID","@value":"9000391964353"},{"@type":"NRID","@value":"9000391964529"},{"@type":"NRID","@value":"9000001638875"},{"@type":"NRID","@value":"9000347547443"},{"@type":"NRID","@value":"9000411102125"},{"@type":"NRID","@value":"9000347547470"},{"@type":"NRID","@value":"9000318581557"},{"@type":"NRID","@value":"9000010700769"},{"@type":"NRID","@value":"9000380967272"},{"@type":"NRID","@value":"9000391966730"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/tfuji2021"}],"foaf:name":[{"@language":"en","@value":"Fujiwara Tomoya"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204171295749","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000403596000"},{"@type":"NRID","@value":"9000005162808"},{"@type":"NRID","@value":"9000009547922"},{"@type":"NRID","@value":"9000254712921"},{"@type":"NRID","@value":"9000001809806"},{"@type":"NRID","@value":"9000403595908"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0018865"}],"foaf:name":[{"@language":"en","@value":"Takeuchi Yoshio"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University"}]},{"@id":"https://cir.nii.ac.jp/crid/1420845751153768576","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"70272010"},{"@type":"NRID","@value":"1000070272010"},{"@type":"NRID","@value":"9000261021048"},{"@type":"NRID","@value":"9000006710371"},{"@type":"NRID","@value":"9000000540896"},{"@type":"NRID","@value":"9000001638880"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0055407"}],"foaf:name":[{"@language":"en","@value":"Omata Kenji"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Chemistry, Graduate School of Science, Tohoku University"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00092363"},{"@type":"EISSN","@value":"13475223"},{"@type":"NDL_BIB_ID","@value":"000000120512"},{"@type":"ISSN","@value":"00092363"},{"@type":"LISSN","@value":"00092363"},{"@type":"NCID","@value":"AA00602100"}],"prism:publicationName":[{"@language":"ja","@value":"ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ"},{"@language":"en","@value":"Chemical and Pharmaceutical Bulletin"},{"@language":"en","@value":"Chem. Pharm. Bull."},{"@language":"en","@value":"CHEMICAL & PHARMACEUTICAL BULLETIN"},{"@language":"ja","@value":"Ｃｈｅｍ．　Ｐｈａｒｍ．　Ｂｕｌｌ．"}],"dc:publisher":[{"@language":"en","@value":"The Pharmaceutical Society of Japan"},{"@language":"ja","@value":"公益社団法人 日本薬学会"}],"prism:publicationDate":"2005","prism:volume":"53","prism:number":"5","prism:startingPage":"524","prism:endingPage":"528"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"http://id.ndl.go.jp/bib/7304526"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I7304526"},{"@id":"http://www.jstage.jst.go.jp/article/cpb/53/5/53_5_524/_pdf"}],"availableAt":"2005","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=2-aryl-2-fluoropropionic%20acid","dc:title":"2-aryl-2-fluoropropionic acid"},{"@id":"https://cir.nii.ac.jp/all?q=isostere","dc:title":"isostere"},{"@id":"https://cir.nii.ac.jp/all?q=non-steroidal%20anti-inflammatory%20drug","dc:title":"non-steroidal anti-inflammatory 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