{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679188906368.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.11441/shinshumedj.54.189"}},{"identifier":{"@type":"HDL","@value":"http://hdl.handle.net/10091/3689"}},{"identifier":{"@type":"URI","@value":"https://soar-ir.repo.nii.ac.jp/records/4236"}},{"identifier":{"@type":"NDL_BIB_ID","@value":"8065756"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/bib/8065756"}},{"identifier":{"@type":"URI","@value":"https://ndlsearch.ndl.go.jp/books/R000000004-I8065756"}},{"identifier":{"@type":"NAID","@value":"130004679668"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2006319283"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@language":"en","@value":"An Investigation of the Diagnosis and Treatment Strategy for Neurally Mediated Syncope Using Head-Up Tilt Testing"},{"@language":"ja","@value":"Head up tilt試験を用いた神経調節性失神（Neurally mediated syncope : NMS）の病型診断と治療戦略の検討"},{"@language":"ja-Kana","@value":"Head up tilt シケン オ モチイタ シンケイ チョウセツセイ シッシン Neurally mediated syncope NMS ノ ビョウケイ シンダン ト チリョウ センリャク ノ ケントウ"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"Neurally mediated syncope (NMS) is an important cause of recurrent syncopal episodes. We performed head-up tilt testing (HUT) with isoproterenol provocation in 27 patients (10 males and 17 females) who were suspected of having NMS between 2001 and 2006 at Joetsu General Hospital. Of the 27 patients, 20 (5 males and 15 females ; mean age, 57.7 years) had syncope ; five of these (25%) had syncope due to bradycardia or cardiac arrest (cardioinhibitory type), 9 (45%) due to hypotension (vasodepressor type), and 6 (30%) due to bradycardia with hypotension (mixed type).<br>We selected treatment methods based on the type of syncope. DDD pacemakers with a rate drop response algorithm were implanted in the patients with the cardioinhibitory type. <i>β</i>-blocking agents and disopyramide were administered to patients with the vasodepressor and mixed types, respectively.<br>During the follow-up period, 17 patients (85%) were syncope-free and two (cardioinhibitory type) had one episode of syncope. However, after adjustment of the pacemaker algorithm, they were syncope-free. One patient (cardioinhibitory type) died from an accidental fall.<br>Careful documentation of history and HUT are necessary for the diagnosis and treatment of NMS. We believe that the prognosis of NMS is good if treatment is selected based on the type of syncope."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410853646835546112","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000259840789"}],"foaf:name":[{"@language":"en","@value":"OTAGIRI Kyuhachi"},{"@language":"ja","@value":"小田切 久八"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Cardiology, Joetsu General Hospital"},{"@language":"ja","@value":"JA新潟厚生連上越総合病院循環器科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410853646835546114","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000259840790"}],"foaf:name":[{"@language":"en","@value":"KAGOSHIMA Mitsuru"},{"@language":"ja","@value":"篭島 充"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"JA新潟厚生連上越総合病院循環器科"},{"@language":"en","@value":"Department of Cardiology, Joetsu General Hospital"}]},{"@id":"https://cir.nii.ac.jp/crid/1410853646835546115","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000259840791"}],"foaf:name":[{"@language":"en","@value":"KINOSHITA Osamu"},{"@language":"ja","@value":"木下 修"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Cardiology, Shinshu University Hospital"},{"@language":"ja","@value":"信州大学医学部附属病院循環器内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1030003658365206915","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"30221063"},{"@type":"NRID","@value":"1000030221063"},{"@type":"NRID","@value":"9000002947483"},{"@type":"NRID","@value":"9000412626612"},{"@type":"NRID","@value":"9000347565521"},{"@type":"NRID","@value":"9000253395894"},{"@type":"NRID","@value":"9000016411580"},{"@type":"NRID","@value":"9000256875066"},{"@type":"NRID","@value":"9000256865104"},{"@type":"NRID","@value":"9000257742538"},{"@type":"NRID","@value":"9000283271904"},{"@type":"NRID","@value":"9000283271862"},{"@type":"NRID","@value":"9000008352124"},{"@type":"NRID","@value":"9000003949248"},{"@type":"NRID","@value":"9000412606135"},{"@type":"NRID","@value":"9000256863342"},{"@type":"NRID","@value":"9000258246658"},{"@type":"NRID","@value":"9000258246776"},{"@type":"NRID","@value":"9000261025508"},{"@type":"NRID","@value":"9000007154618"},{"@type":"NRID","@value":"9000316692518"},{"@type":"NRID","@value":"9000287355193"},{"@type":"NRID","@value":"9000006244972"},{"@type":"NRID","@value":"9000391583431"},{"@type":"NRID","@value":"9000347212755"},{"@type":"NRID","@value":"9000290819432"},{"@type":"NRID","@value":"9000255953197"},{"@type":"NRID","@value":"9000256881222"},{"@type":"NRID","@value":"9000259842930"},{"@type":"NRID","@value":"9000021415497"},{"@type":"NRID","@value":"9000363178471"},{"@type":"NRID","@value":"9000259840792"},{"@type":"NRID","@value":"9000258309540"},{"@type":"NRID","@value":"9000007877392"},{"@type":"NRID","@value":"9000238238248"},{"@type":"NRID","@value":"9000363354175"},{"@type":"NRID","@value":"9000021357404"},{"@type":"NRID","@value":"9000243898766"},{"@type":"NRID","@value":"9000253543384"},{"@type":"NRID","@value":"9000256874714"},{"@type":"NRID","@value":"9000020605724"},{"@type":"NRID","@value":"9000022118385"},{"@type":"NRID","@value":"9000319052701"},{"@type":"NRID","@value":"9000253466836"},{"@type":"NRID","@value":"9000255955469"},{"@type":"NRID","@value":"9000256881221"},{"@type":"NRID","@value":"9000258246829"},{"@type":"NRID","@value":"9000319052645"},{"@type":"NRID","@value":"9000314067698"},{"@type":"NRID","@value":"9000253227367"},{"@type":"NRID","@value":"9000283493737"},{"@type":"NRID","@value":"9000272259266"},{"@type":"NRID","@value":"9000003158466"},{"@type":"NRID","@value":"9000412626600"},{"@type":"NRID","@value":"9000004063318"},{"@type":"NRID","@value":"9000255814315"},{"@type":"NRID","@value":"9000256866045"},{"@type":"NRID","@value":"9000001090024"},{"@type":"NRID","@value":"9000309566381"},{"@type":"NRID","@value":"9000022009606"},{"@type":"NRID","@value":"9000402921581"},{"@type":"NRID","@value":"9000402071888"},{"@type":"NRID","@value":"9000261658394"},{"@type":"NRID","@value":"9000391915600"},{"@type":"NRID","@value":"9000391584281"},{"@type":"NRID","@value":"9000252930112"},{"@type":"NRID","@value":"9000253544145"},{"@type":"NRID","@value":"9000256881667"},{"@type":"NRID","@value":"9000258572927"},{"@type":"NRID","@value":"9000018131865"},{"@type":"NRID","@value":"9000018751665"},{"@type":"NRID","@value":"9000021376618"},{"@type":"NRID","@value":"9000391584433"},{"@type":"NRID","@value":"9000283633658"},{"@type":"NRID","@value":"9000252753473"},{"@type":"NRID","@value":"9000283633431"},{"@type":"NRID","@value":"9000258246943"},{"@type":"NRID","@value":"9000389566925"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0116412"}],"foaf:name":[{"@language":"en","@value":"IKEDA Uichi"},{"@language":"ja","@value":"池田 宇一"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Cardiology, Shinshu University Hospital"},{"@language":"ja","@value":"信州大学医学部附属病院循環器内科"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00373826"},{"@type":"EISSN","@value":"18846580"},{"@type":"NDL_BIB_ID","@value":"000000012094"},{"@type":"ISSN","@value":"00373826"},{"@type":"LISSN","@value":"00373826"},{"@type":"NCID","@value":"AN00120815"}],"prism:publicationName":[{"@language":"en","@value":"THE SHINSHU MEDICAL JOURNAL"},{"@language":"ja","@value":"信州医学雑誌"},{"@language":"en","@value":"SHINSHU MED J"},{"@language":"ja","@value":"信州医誌"}],"dc:publisher":[{"@language":"en","@value":"The Shinshu Medical Society"},{"@language":"ja","@value":"信州医学会"}],"prism:publicationDate":"2006","prism:volume":"54","prism:number":"4","prism:startingPage":"189","prism:endingPage":"195"},"url":[{"@id":"https://soar-ir.repo.nii.ac.jp/records/4236"},{"@id":"http://id.ndl.go.jp/bib/8065756"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I8065756"},{"@id":"http://hdl.handle.net/10091/3689"},{"@id":"https://search.jamas.or.jp/link/ui/2006319283"}],"availableAt":"2006","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=neurally%20mediated%20syncope","dc:title":"neurally mediated syncope"},{"@id":"https://cir.nii.ac.jp/all?q=head-up%20tilt%20test","dc:title":"head-up tilt test"},{"@id":"https://cir.nii.ac.jp/all?q=disopyramide","dc:title":"disopyramide"},{"@id":"https://cir.nii.ac.jp/all?q=%3Ci%3E%CE%B2%3C/i%3E-blocker","dc:title":"<i>β</i>-blocker"},{"@id":"https://cir.nii.ac.jp/all?q=%E7%A5%9E%E7%B5%8C%E8%AA%BF%E7%AF%80%E6%80%A7%E5%A4%B1%E7%A5%9E","dc:title":"神経調節性失神"},{"@id":"https://cir.nii.ac.jp/all?q=%E3%83%98%E3%83%83%E3%83%89%E3%82%A2%E3%83%83%E3%83%97%E3%83%86%E3%82%A3%E3%83%AB%E3%83%88%E8%A9%A6%E9%A8%93","dc:title":"ヘッドアップティルト試験"},{"@id":"https://cir.nii.ac.jp/all?q=%E3%82%B8%E3%82%BD%E3%83%94%E3%83%A9%E3%83%9F%E3%83%89","dc:title":"ジソピラミド"},{"@id":"https://cir.nii.ac.jp/all?q=%3Ci%3E%CE%B2%3C/i%3E-blocker","dc:title":"<i>β</i>-blocker"}],"dcterms:subject":[{"subjectScheme":"Other","notation":[{"@language":"en","@value":"neurally mediated syncope"}]},{"subjectScheme":"Other","notation":[{"@language":"en","@value":"head-up tilt test"}]},{"subjectScheme":"Other","notation":[{"@language":"en","@value":"disopyramide"}]},{"subjectScheme":"Other","notation":[{"@language":"en","@value":"β-blocker"}]},{"subjectScheme":"Other","notation":[{"@language":"ja","@value":"神経調節性失神"}]},{"subjectScheme":"Other","notation":[{"@language":"ja","@value":"ヘッドアップティルト試験"}]},{"subjectScheme":"Other","notation":[{"@language":"ja","@value":"ジソピラミド"}]},{"subjectScheme":"Other","notation":[{"@language":"en","@value":"β-blocker"}]}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:0028306195"},{"@type":"IRDB","@value":"oai:irdb.nii.ac.jp:00990:0001368625"},{"@type":"NDL_SEARCH","@value":"oai:ndlsearch.ndl.go.jp:R000000004-I8065756"},{"@type":"CIA","@value":"130004679668"}]}