{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679217313664.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1620/tjem.210.247"}},{"identifier":{"@type":"URI","@value":"http://www.jstage.jst.go.jp/article/tjem/210/3/210_3_247/_pdf"}},{"identifier":{"@type":"NAID","@value":"10018349792"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2007200787"}}],"dc:title":[{"@language":"en","@value":"Persistent Oxidative Stress after Myocardial Infarction Treated by Percutaneous Coronary Intervention"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"Acute myocardial infarction causing cardiac ischemia is responsible for the majority of cardiac related deaths.  Medical interventions that ensure rapid reperfusion, such as percutaneous coronary intervention, are aimed to allow myocardial re-oxygenation.  However, this generates reactive oxygen species, resembling ischemia-reperfusion type of injury based on oxidative stress.  In the present study we monitored dynamic changes of total serum peroxides, total antioxidant capacity and soluble intercellular adhesion molecule-1 as well as the titer of antibodies against oxidized low-density lipoproteins in the blood during the convalescence period of 32 patients with acute myocardial infarction treated by percutaneous coronary intervention.  Samples were taken at admittance and at two hours, four hours, three days and seven days following percutaneous coronary intervention.  Total antioxidant capacity dropped to 82% (<i>p</i> < 0.05).  The titer of antibodies against oxidized low-density lipoproteins transiently decreased within the first three days, and increased afterwards.  The values of serum peroxides and soluble intercellular adhesion molecule-1 increased continuously in respect to the initial levels reaching the maximum at the time of release from hospital.  These findings indicate a persistent oxidative stress that might be associated with intravascular inflammation in patients during convalescence and release from hospital."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410282679217313666","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000001840448"}],"foaf:name":[{"@language":"en","@value":"Nikolic-Heitzler Vjeran"}],"jpcoar:affiliationName":[{"@language":"en","@value":"University Clinical Hospital “Sestre milosrdnice”"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679217313671","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000001840450"}],"foaf:name":[{"@language":"en","@value":"Rabuzin Filip"}],"jpcoar:affiliationName":[{"@language":"en","@value":"“Rudjer Boskovic” Institute, Division of Molecular Medicine"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679217313668","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000001840452"}],"foaf:name":[{"@language":"en","@value":"Tatzber Franz"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Nuclear Medicine, University of Vienna"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679217313667","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000001840454"}],"foaf:name":[{"@language":"en","@value":"Vrkic Nada"}],"jpcoar:affiliationName":[{"@language":"en","@value":"University Clinical Hospital “Sestre milosrdnice”"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679217313664","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000001840456"}],"foaf:name":[{"@language":"en","@value":"Bulj Nikola"}],"jpcoar:affiliationName":[{"@language":"en","@value":"University Clinical Hospital “Sestre milosrdnice”"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679217313665","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000001840458"}],"foaf:name":[{"@language":"en","@value":"Borovic Suzana"}],"jpcoar:affiliationName":[{"@language":"en","@value":"“Rudjer Boskovic” Institute, Division of Molecular Medicine"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679217313672","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000001840460"}],"foaf:name":[{"@language":"en","@value":"Wonisch Willibald"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679217313670","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000001840462"}],"foaf:name":[{"@language":"en","@value":"Sunko Branka Mazul"}],"jpcoar:affiliationName":[{"@language":"en","@value":"University Clinical Hospital “Sestre milosrdnice”"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679217313669","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000001840464"}],"foaf:name":[{"@language":"en","@value":"Zarkovic Neven"}],"jpcoar:affiliationName":[{"@language":"en","@value":"“Rudjer Boskovic” Institute, Division of Molecular Medicine"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00408727"},{"@type":"EISSN","@value":"13493329"},{"@type":"NCID","@value":"AA00863920"}],"prism:publicationName":[{"@language":"en","@value":"The Tohoku Journal of Experimental Medicine"},{"@language":"en","@value":"Tohoku J. Exp. Med."}],"dc:publisher":[{"@language":"en","@value":"Tohoku University Medical Press"},{"@language":"ja","@value":"東北ジャーナル刊行会"}],"prism:publicationDate":"2006","prism:volume":"210","prism:number":"3","prism:startingPage":"247","prism:endingPage":"255"},"reviewed":"false","url":[{"@id":"http://www.jstage.jst.go.jp/article/tjem/210/3/210_3_247/_pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2007200787"}],"availableAt":"2006","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=myocardial%20infarction","dc:title":"myocardial infarction"},{"@id":"https://cir.nii.ac.jp/all?q=percutaneous%20coronary%20intervention","dc:title":"percutaneous coronary intervention"},{"@id":"https://cir.nii.ac.jp/all?q=inflammation","dc:title":"inflammation"},{"@id":"https://cir.nii.ac.jp/all?q=soluble%20intercellular%20adhesion%20molecule-1","dc:title":"soluble intercellular adhesion molecule-1"},{"@id":"https://cir.nii.ac.jp/all?q=lipid%20peroxidation","dc:title":"lipid peroxidation"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360292618921424896","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Uric acid reduces exercise-induced oxidative stress in healthy adults"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619098715008","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Oxidative Stress and Vascular Disease"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574095935799936","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Attenuation of antioxidative capacity enhances reperfusion injury in aged rat myocardium after MI/R"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855569925273344","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Pretreatment with antioxidants and allopurinol diminishes cardiac onset events in coronary artery bypass 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