書誌事項
- タイトル別名
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- A Fundamental and Clinical Study of AM-715 in the Otorhinolaryngologic Field
- ジビ インコウカ リョウイキ カンセンショウ ニ オケル AM 715 ノ キ
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説明
A fundamental and clinical study of AM-715 was carried out with the following results.<br>1. AM-715 was administered to 78 patients with infection in the field of otorhinolaryngology. The effective results were obtained as follows: 100% in acute suppurative otitis media, 78% in acute exacerbation of chronic otitis media, 70% in sinusitis and 80% in tonsillitis.<br>2. The antibacterial activity of AM-715 was superior to that of pipemidic acid against S. aureus, β-Streptococcus Group A, S. pneumoniae and P. aeruginosa.<br>3. The peak level of AM-715 in aural discharge was 0.47μg/ml four hours after a single oral dosing of 200mg and 0.64μg/ml three hours after a single oral dosing of 400mg.<br>4. Vertigo was observed in 2 (2.5%), nausea and diarrhoea in 1 (1.3%) of the 78 patients treated with AM-715.<br>5. AM-715 is a useful antibacterial agent in the field of otorhinolaryngologic infections.
収録刊行物
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- 耳鼻咽喉科臨床
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耳鼻咽喉科臨床 75 (9), 1859-1865, 1982
耳鼻咽喉科臨床学会
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390282679240265984
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- NII論文ID
- 130001809814
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- NII書誌ID
- AN00107089
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- ISSN
- 18844545
- 00326313
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- NDL書誌ID
- 2499313
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可