{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679277344256.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.2336/nishinihonhifu.34.553"}},{"identifier":{"@type":"NDL_BIB_ID","@value":"7602002"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/bib/7602002"}},{"identifier":{"@type":"URI","@value":"https://ndlsearch.ndl.go.jp/books/R000000004-I7602002"}},{"identifier":{"@type":"NAID","@value":"130004472085"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/1972105410"}}],"dc:title":[{"@language":"en","@value":"On Pathogenesis of the Fixed Drug Eruption"},{"@language":"ja","@value":"固定薬疹の発生機序について"},{"@value":"固定薬疹の発生機序について Epidermis affinity antibody(仮称)の提唱(樋口謙太郎教授退官記念特別講演)"},{"@language":"ja-Kana","@value":"コテイヤクシン ノ ハッセイ キジョ ニ ツイテ Epidermis affinity antibody カショウ ノ テイショウ ヒグチケンタロウ キョウジュ タイカン キネン トクベツ コウエン"}],"dcterms:alternative":[{"@language":"en","@value":"—Proposition of Epidermis Affinity Antibody (A Provisional Name)—"},{"@language":"ja","@value":"—Epidermis Affinity Antibody(仮称)の提唱—"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"1) After being taken orally, a causal agent (hapten) is combined with the mucous membrane to form anti-hapten-mucosa antibody.<BR> 2) This antibody has chemotaxis to the orifice regions through its carrier specificity.<BR> 3) When a sensitized subject takes a causal drug orally, a new fixed drug eruption would develop on a region inflamed and congested for some time by insect bite, fungal or bacterial infection etc., because the concentration of antigen and antibody rises there.<BR> 4) The keratinocytes and dermal macrophages take the antigen-antibody complexes and give the antigenic information to the lymphocytes through the macrophages of a regional lymphnode, where the epidermis affinity antibody is much more produced."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410853646480280448","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000257928707"}],"foaf:name":[{"@language":"en","@value":"TANIOKU Kihei"},{"@language":"ja","@value":"谷奥 喜平"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Dermatology, Faculty of Medicine, Okayama University"},{"@language":"ja","@value":"岡山大学医学部皮膚科教室"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"03869784"},{"@type":"LISSN","@value":"03869784"},{"@type":"EISSN","@value":"18804047"},{"@type":"NDL_BIB_ID","@value":"000000017954"},{"@type":"ISSN","@value":"03869784"},{"@type":"NCID","@value":"AN00183881"}],"prism:publicationName":[{"@language":"en","@value":"The Nishinihon Journal of Dermatology"},{"@language":"ja","@value":"西日本皮膚科"},{"@language":"en","@value":"Nishinihon J Dermatol"},{"@language":"en","@value":"Nishi Nihon Hifuka"},{"@language":"ja","@value":"西日皮膚"}],"dc:publisher":[{"@language":"en","@value":"Western Division of Japanese Dermatological Association"},{"@language":"ja","@value":"日本皮膚科学会西部支部"}],"prism:publicationDate":"1972","prism:volume":"34","prism:number":"5","prism:startingPage":"553","prism:endingPage":"566"},"reviewed":"false","url":[{"@id":"http://id.ndl.go.jp/bib/7602002"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I7602002"},{"@id":"https://search.jamas.or.jp/link/ui/1972105410"}],"availableAt":"1972","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Dermatology","dc:title":"Dermatology"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360011145386183552","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Fixed Drug Eruption Caused by 8-Chlorotheophylline in Dramamine® with Clinical and Histologic Studies††From the Division of Dermatology, Department of Medicine, State University of New York, Downstate Medical Center, New York City, New York."}]},{"@id":"https://cir.nii.ac.jp/crid/1360011146027767552","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"DRUG ERUPTIONS"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011146557982464","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Morbilliform Eruptions Caused by Penicillin**From the Departments of Dermatology and Cell. 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