{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679277443712.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.2336/nishinihonhifu.62.99"}},{"identifier":{"@type":"NAID","@value":"10019105392"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2000160612"}}],"dc:title":[{"@language":"en","@value":"Dermatological Operation Using an Artificial Dermis \"Terudermis\"."},{"@language":"ja","@value":"人工真皮テルダーミスを使用した皮膚科手術例"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"Deep wounds resulting in exposed bones or tendons are difficult to treat with skin grafts and are often repaired by a musculocutaneous or other conventional skin flaps. We tried to treat such cases using an artificial dermis “Terudermis” (AD-T) without skin flaps. The cases included an 81-year-old woman with malignant hemangioendothelioma exposed scalp bone after a wide excision of the tumor and an 87-year-old man with necrotizing fasciitis exposed muscles and tendons after undergoing extensive debridement. The skin defects could be covered with autologous split-thickness skin grafts on the 25th and the 21th days after applying AD-T, respectively. We further used this method on two cases with moderate skin defects after an excision of both eccrine poroma on the sole and acquired digital fibrokeratoma on the third finger. We confirmed that the application of AD-T can accelerate well vascularized granulation on poor wound beds, allowing us to easily treat deep defects with skin grafts and reduce mental and physical stress for older patients who need to undergo an operation. By expanding the adaptability of AD-T, dermatologists will surely be able to operate on a larger number of cases with skin defects."},{"@language":"ja","@value":"骨が露出した頭部の悪性血管内皮細胞腫の拡大切除,および筋,腱が露出した下腿の壊死性筋膜炎のデブリドマン後の重度皮膚欠損例に対して,真皮欠損用グラフト·テルダーミス<sup>®</sup>(AD-T)を貼付し,二期的に分層植皮を行い良好に治癒した症例を経験した。また,足底および爪部の良性腫瘍切除後の軽度皮膚欠損症例にも試用した。AD-Tを使用することにより,従来,遊離植皮単独では治療適応外であった症例にも,遊離植皮を利用しての修復が可能となり,比較的簡略に創面を閉鎖することができた。AD-Tは,高齢者などの皮弁形成術では手術侵襲が大きく治療困難な症例や,全身状態が悪く皮膚欠損部の母床の形成が不良な症例にも,遊離植皮単独での治療を可能にするものと考えた。皮膚科領域でもAD-Tの適応可能な症例は多く,使用法を自由に工夫することにより,今後使用例が増えるものと思われた。"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410001204297906693","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000006222494"},{"@type":"NRID","@value":"9000257938619"},{"@type":"NRID","@value":"9000259846364"},{"@type":"NRID","@value":"9000259846687"},{"@type":"NRID","@value":"9000259845429"},{"@type":"NRID","@value":"9000257938305"}],"foaf:name":[{"@language":"en","@value":"IIJIMA Shigeruko"},{"@language":"ja","@value":"飯島 茂子"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Division of Dermatology, Mito Saiseikai General Hospital"},{"@language":"ja","@value":"水戸済生会総合病院皮膚科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679277443712","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000001934616"}],"foaf:name":[{"@language":"en","@value":"MIYATA Miho"},{"@language":"ja","@value":"宮田 美穂"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Division of Dermatology, Mito Saiseikai General Hospital"},{"@language":"ja","@value":"水戸済生会総合病院皮膚科"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"03869784"},{"@type":"LISSN","@value":"03869784"},{"@type":"EISSN","@value":"18804047"},{"@type":"NCID","@value":"AN00183881"}],"prism:publicationName":[{"@language":"en","@value":"The Nishinihon Journal of Dermatology"},{"@language":"ja","@value":"西日本皮膚科"},{"@language":"en","@value":"Nishinihon J Dermatol"},{"@language":"en","@value":"Nishi Nihon Hifuka"},{"@language":"ja","@value":"西日皮膚"}],"dc:publisher":[{"@language":"en","@value":"Western Division of Japanese Dermatological Association"},{"@language":"ja","@value":"日本皮膚科学会西部支部"}],"prism:publicationDate":"2000","prism:volume":"62","prism:number":"1","prism:startingPage":"99","prism:endingPage":"106"},"reviewed":"false","url":[{"@id":"https://search.jamas.or.jp/link/ui/2000160612"}],"availableAt":"2000","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Dermatology","dc:title":"Dermatology"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1390001204960275328","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A new type collagen matrix reconstructed self connective tissue."},{"@value":"自己組織を再構築させる新タイプのコラーゲン材料"}]},{"@id":"https://cir.nii.ac.jp/crid/1522543655180731776","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"人工真皮テルダーミスの皮膚全層欠損臨床使用55例の検討--短期総合評価と有用性および使用上の検討"},{"@language":"ja-Kana","@value":"ジンコウ シンピ テルダーミス ノ ヒフ ゼンソウ ケッソン リンショウ シヨ"}]},{"@id":"https://cir.nii.ac.jp/crid/1570009751263481856","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"壊疽性膿皮症を疑った難治性下腿潰瘍に人工真皮を応用した1例"}]},{"@id":"https://cir.nii.ac.jp/crid/1570572700118145792","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"人工真皮SS-Dの皮膚全層欠損部使用例の検討 : 動物実験における経時組織学的検討および瘢痕組織との比較"},{"@language":"en","@value":"A Study of an Artificial Dermis SS-D for Full Thickness Skin Defect : A Histological study of neodermis and its difference from scar tissue in animal research"}]},{"@id":"https://cir.nii.ac.jp/crid/1570572700498158336","@type":"Article","relationType":["cites"]},{"@id":"https://cir.nii.ac.jp/crid/1570572701734005760","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"皮膚欠損用グラフト (SS-D) を用いた臨床使用例の検討"}]},{"@id":"https://cir.nii.ac.jp/crid/1571135651683016064","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"真皮欠損用グラフト (SS-D) の臨床使用"}]},{"@id":"https://cir.nii.ac.jp/crid/1571698601124506752","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"人工真皮テルダーミス^( !R)の使用上の工夫による治療効果の拡大"}]},{"@id":"https://cir.nii.ac.jp/crid/1572543026560310016","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"テルダーミス真皮欠損用グラフトの重度真皮欠損創への臨床応用"}]},{"@id":"https://cir.nii.ac.jp/crid/1572543026579205888","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"新しい真皮欠損用グラフト (ネオマトリックス) の重度の皮膚欠損創に対する臨床効果"}]},{"@id":"https://cir.nii.ac.jp/crid/1572824500500482688","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"人工真皮を用いて治療した外果部褥創の1例"}]},{"@id":"https://cir.nii.ac.jp/crid/1573105975649483776","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"皮膚欠損用グラフト (SS-D) の外用が奏効した褥瘡治療の試み"}]},{"@id":"https://cir.nii.ac.jp/crid/1573105976514302336","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"真皮用グラフト (SS-D) の口腔粘膜欠損への使用経験"}]},{"@id":"https://cir.nii.ac.jp/crid/1573668925242096896","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"再建に人工真皮を使用した足踵悪性腫瘍の1治験例"}]},{"@id":"https://cir.nii.ac.jp/crid/1573950400218808064","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"アキレス腱露出創に人工真皮 (テルダーミス) を用いて可動制限を生じなかった1症例"}]}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:0008704432"},{"@type":"CROSSREF","@value":"10.2336/nishinihonhifu.62.99"},{"@type":"CIA","@value":"10019105392"}]}