{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679308473472.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1589/jpts.29.685"}},{"identifier":{"@type":"URI","@value":"https://www.jstage.jst.go.jp/article/jpts/29/4/29_jpts-2016-864/_pdf"}},{"identifier":{"@type":"NAID","@value":"130006789355"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2018127519"}}],"dc:title":[{"@language":"en","@value":"Effects of transcutaneous electrical nerve stimulation on chemotherapy-induced peripheral neuropathy symptoms (CIPN): a preliminary case-control study"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"<p> [Purpose] The aim of this double-blind, randomized and placebo-controlled study is to investigate the effects of Transcutaneous Electrical Nerve Stimulation for reducing the side effects of Chemotherapy-induced Peripheral Neuropathy in cancer patients undergoing chemotherapy with oxaloplatin or paclitaxel. [Subjects and Methods] Twenty-four patients were randomly allocated into two groups: active or placebo stimulation. All patients were assessed for pain, numbness/tingiling, frequency of symptoms, and quality of life. The transcutaneous Electrical Nerve Stimulation device was applied daily with modulating frequencies ranging between 7 Hz and 65 Hz in distal limb regions during three cycles of chemotherapy (45 days). The other stimulation parameters were: pulse duration of 200 μsec, intensity at the highest tolerable level, and increases in intensity when it diminished. [Results] The data showed no difference between active or placebo groups in terms of pain, numbness/tingling, frequency of symptoms or impact on daily life activities. [Conclusion] These results suggest that Transcutaneous Electrical Nerve Stimulation applied in the frequency variation mode was not proven to be effective to improve the symptoms of Chemotherapy-induced Peripheral Neuropathy during chemotherapy cycles. There was no worsening of symptoms in subsequent cycles of the onset of symptoms of the disease.</p>"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410282679308473476","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000391407593"}],"foaf:name":[{"@language":"en","@value":"Tonezzer Tania"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Rehabilitation Sciences in the School of Medicine,              Department of Physical Therapy, Speech and Occupational Therapy, University of São              Paulo, Brazil"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679308473474","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000391407594"}],"foaf:name":[{"@language":"en","@value":"Caffaro Leonardo Affonso Massabki"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Rehabilitation Sciences in the School of Medicine,              Department of Physical Therapy, Speech and Occupational Therapy, University of São              Paulo, Brazil"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679308473477","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000391407595"}],"foaf:name":[{"@language":"en","@value":"Menon Katiuscia Rosette Scasni"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Physiotherapy Course of University of São Francisco, Brazil"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679308473475","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000391407596"}],"foaf:name":[{"@language":"en","@value":"Brandini da Silva Fabíola Cristina"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Barretos Cancer Hospital, Brazil"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679308473472","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000391407597"}],"foaf:name":[{"@language":"en","@value":"Moran de Brito Christina May"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Rehabilitation Department of the Cancer Institute at the University of São Paulo School of Medicine, Brazil"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679308473478","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000391407598"}],"foaf:name":[{"@language":"en","@value":"Sarri Almir José"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Physiotherapy, Barretos Cancer Hospital, Brazil"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679308473473","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000391407599"}],"foaf:name":[{"@language":"en","@value":"Casarotto Raquel Aparecida"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Physical Therapy, Speech and Occupational Therapy, School of Medicine of the University of São Paulo, Brazil"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"09155287"},{"@type":"LISSN","@value":"09155287"},{"@type":"EISSN","@value":"21875626"}],"prism:publicationName":[{"@language":"en","@value":"Journal of Physical Therapy Science"},{"@language":"en","@value":"J Phys Ther Sci"},{"@language":"ja","@value":"Ｊ　Ｐｈｙｓ　Ｔｈｅｒ　Ｓｃｉ"}],"dc:publisher":[{"@language":"en","@value":"The Society of Physical Therapy Science"},{"@language":"ja","@value":"理学療法科学学会"}],"prism:publicationDate":"2017","prism:volume":"29","prism:number":"4","prism:startingPage":"685","prism:endingPage":"692"},"reviewed":"false","url":[{"@id":"https://www.jstage.jst.go.jp/article/jpts/29/4/29_jpts-2016-864/_pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2018127519"}],"availableAt":"2017","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Transcutaneous%20electric%20nerve%20stimulation","dc:title":"Transcutaneous electric nerve stimulation"},{"@id":"https://cir.nii.ac.jp/all?q=Chemotherapy-induced%20peripheral%20neuropathy","dc:title":"Chemotherapy-induced peripheral neuropathy"},{"@id":"https://cir.nii.ac.jp/all?q=Physical%20therapy","dc:title":"Physical therapy"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360011143921949440","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505)"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011144302426624","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Electrical Stimulation to Enhance Axon Regeneration After Peripheral Nerve Injuries in Animal Models and Humans"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011146162669312","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Pilot evaluation of Scrambler therapy for the treatment of chemotherapy-induced peripheral 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