{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679332759040.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.2116/bunsekikagaku.17.1309"}},{"identifier":{"@type":"NDL_BIB_ID","@value":"8442840"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/bib/8442840"}},{"identifier":{"@type":"URI","@value":"https://ndlsearch.ndl.go.jp/books/R000000004-I8442840"}},{"identifier":{"@type":"URI","@value":"http://www.jstage.jst.go.jp/article/bunsekikagaku1952/17/10/17_10_1309/_pdf"}},{"identifier":{"@type":"NAID","@value":"130000944565"}}],"dc:title":[{"@language":"en","@value":"Radiometric titration of organic mercury, inorganic mercury, lead, cadmium and nickel with penicillamine."},{"@value":"ペニシラミンによる有機水銀,無機水銀,鉛,カドミウムおよびニッケルの放射滴定"},{"@language":"ja-Kana","@value":"ペニシラミン ニ ヨル ユウキ スイギン , ムキ スイギン , ナマリ , カドミウム オヨビ ニッケル ノ ホウシャ テキテイ"}],"dcterms:alternative":[{"@language":"en","@value":"Studies on the sulfur-containing chelating agents. XVIII."},{"@value":"イオウを含むキレート試薬に関する研究(第18報)"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"A new radiometric titration method for determination of heavy metals, such as organic mercury, inorganic mercury, lead, cadmium and nickel, was developed in which penicillamine and cobalt-60 were used as a titrant and a non-isotopic tracer, respectively. A series of sample solution of equal volume is prepared, and the tracer is added to each solution. Penicillamine solution is added to it, and the amount of penicillamine to be added to each solution is increased stepwise. The activity of the solution is measured, after the resulted mixture is treated with cation exchange resin. <BR>A titration curve is drawn, and its end-point is clearly observed as the jump of activity. The principle of this method is based on the facts that above mentioned metal ions form negatively charged or neutral chelates of much higher stability than cobalt, and the chelates can be separated easily from the excess of unreacting cobalt ion by ion-exchange resin. The activity then appears in the solution when the amount of penicillamine becomes excess to the amount of metal ion in the sample. The determination of 10<SUP>-6</SUP>10<SUP>-7</SUP><I>M</I> of organic mercury, inorganic mercury, lead, cadmium and nickel was possible, 10<SUP>-5</SUP><I>M</I> solution of penicillamine and 10<SUP>-5</SUP><I>M</I> of cobalt-60 solution being used within the range of pH value 8.812.<BR>The limit of this method was discussed through the stability constant of metal chelates. Determination of mercury using mercury-203 as an isotopic tracer was also possible."},{"@value":"<SUP>60</SUP>Coを放射性指示薬としたペニシラミンによる微量有機水銀,無機水銀,鉛,カドミウムなどの重金属類の放射滴定法について検討を行なった.本法は,ペニシラミンの水銀や鉛などの重金属に対するキレート生成能が,コバルトに対するキレート生成能よりもはるかに大きいことを利用する方法である.試料溶液に<SUP>60</SUP>Coをトレーサーとして加え,これにペニシラミン量を順次増して添加し,生成キレートと遊離金属イオンとを陽イオン交換樹脂(Dowex 50W-X8)を用いて分離する.溶出液の放射能強度と添加ペニシラミン量との関係から滴定曲線を作成する.本法によって,10<SUP>-6</SUP>～10<SUP>-7</SUP><I>M</I>程度の有機水銀,無機水銀,鉛,カドミウムおよびニッケルについては滴定が可能であるが.コバルトキレートよりも生成定数の小さい鉄やマンガンについては滴定することはできない.また.<SUP>203</SUP>Hgをトレーサーとする微量水銀の放射滴定法についても検討を行なった."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410853646576101636","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000021900334"}],"foaf:name":[{"@language":"en","@value":"TANAKA Hisashi"},{"@language":"ja","@value":"田中 久"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Faculty of Pharmaceutical Science, Kyoto 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Yukio"},{"@language":"ja","@value":"杉浦 幸雄"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Faculty of Pharmaceutical Science, Kyoto University"},{"@language":"ja","@value":"京都大学薬学部"}]},{"@id":"https://cir.nii.ac.jp/crid/1410853646576101633","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000021900340"}],"foaf:name":[{"@language":"en","@value":"SEKI Keiko"},{"@language":"ja","@value":"関 啓子"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Faculty of Pharmaceutical Science, Kyoto University"},{"@language":"ja","@value":"京都大学薬学部"}]},{"@id":"https://cir.nii.ac.jp/crid/1410853646576101632","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000021900345"}],"foaf:name":[{"@language":"en","@value":"SAKAGUCHI Kimiko"},{"@language":"ja","@value":"阪口 喜美子"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"京都大学薬学部"},{"@language":"en","@value":"Faculty of Pharmaceutical Science, Kyoto 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陽"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Faculty of Pharmaceutical Science, Kyoto University"},{"@language":"ja","@value":"京都大学薬学部"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"05251931"},{"@type":"NDL_BIB_ID","@value":"000000021279"},{"@type":"ISSN","@value":"05251931"},{"@type":"LISSN","@value":"05251931"},{"@type":"NCID","@value":"AN00222633"}],"prism:publicationName":[{"@language":"ja","@value":"分析化学"},{"@language":"en","@value":"BUNSEKI KAGAKU"},{"@language":"en","@value":"BUNSEKI KAGAKU"},{"@language":"en","@value":"Bunseki kagaku"},{"@language":"ja","@value":"分析化学"}],"dc:publisher":[{"@language":"en","@value":"The Japan Society for Analytical Chemistry"},{"@language":"ja","@value":"公益社団法人 日本分析化学会"}],"prism:publicationDate":"1968","prism:volume":"17","prism:number":"10","prism:startingPage":"1309","prism:endingPage":"1315"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"http://id.ndl.go.jp/bib/8442840"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I8442840"},{"@id":"http://www.jstage.jst.go.jp/article/bunsekikagaku1952/17/10/17_10_1309/_pdf"}],"availableAt":"1968","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Analytical%20Chemistry","dc:title":"Analytical Chemistry"}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:0037155888"},{"@type":"NDL_SEARCH","@value":"oai:ndlsearch.ndl.go.jp:R000000004-I8442840"},{"@type":"CROSSREF","@value":"10.2116/bunsekikagaku.17.1309"},{"@type":"CIA","@value":"130000944565"},{"@type":"OPENAIRE","@value":"doi_dedup___::5e89ed64d4d32435f5f9796f65318afc"}]}