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Evidence of Improvement in Various Impairments by Exercise Interventions in Patients with Knee Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Clinical Trials
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- TANAKA Ryo
- Department of Integrated Rehabilitation, Hiroshima International University
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- OZAWA Junya
- Department of Integrated Rehabilitation, Hiroshima International University
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- KITO Nobuhiro
- Department of Integrated Rehabilitation, Hiroshima International University
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- YAMASAKI Takahiro
- Department of Integrated Rehabilitation, Hiroshima International University
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- MORIYAMA Hideki
- Department of Rehabilitation Science, Kobe University Graduate School of Health Sciences
Bibliographic Information
- Other Title
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- 変形性膝関節症患者に対する運動介入による機能障害の改善のエビデンス：ランダム化比較試験に対するシステマティックレビューおよびメタアナリシス
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Description
Purpose: To investigate improvement in various impairments by exercise interventions in patients with knee osteoarthritis (OA). Methods: We collected data on randomized controlled trials (RCTs) comparing the effects of exercise intervention with those of either nonintervention or psychoeducational intervention in patients with knee OA. Data on pain, stiffness, muscle strength, range of motion, flexibility, maximal oxygen uptake, and position sense were synthesized. The Grading of Recommendations Assessment, Development, and Evaluation system was used to determine the quality of the evidence. Results: Thirty-three RCTs involving 3,192 participants were identified. Meta-analysis provided highquality evidence that exercise intervention improves maximal oxygen uptake, and moderate-quality evidence that exercise intervention also improves pain, stiffness, knee extensor and flexor muscle strength, and position sense. The evidence that exercise intervention improves knee extension and flexion range of motion was deemed as undetermined-quality. Conclusion: In patients with knee OA, improvement in pain, stiffness, muscle strength, maximal oxygen uptake, and position sense with the use of exercise intervention can be expected. Although the quality of evidence of the effect of exercise intervention on range of motion was inconclusive, exercise intervention should be recommended for patients with knee OA to improve various impairments.
Journal
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- Journal of the Japanese Physical Therapy Association
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Journal of the Japanese Physical Therapy Association 16 (1), 7-21, 2013
Japanese Physical Therapy Association(Renamed Japanese Society of Physical Therapy)