{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679552777088.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1246/cl.1999.53"}},{"identifier":{"@type":"COI","@value":"1:CAS:528:DyaK1MXktFOksQ%3D%3D"}},{"identifier":{"@type":"URI","@value":"https://academic.oup.com/chemlett/article-pdf/28/1/53/56077044/cl.1999.53.pdf"}},{"identifier":{"@type":"NAID","@value":"130004421241"}}],"dc:title":[{"@language":"en","@value":"Intracellular Responses of Hybrid Liposomes against Leukemia Cells Related to Apoptosis with Antitumor Activity"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"Intracellular responses of hybrid liposomes against leukemia cells related to apotosis were observed for the first time along with the highly inhibitory effects."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1420001326215674112","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"00133562"},{"@type":"NRID","@value":"1000000133562"},{"@type":"NRID","@value":"9000021803517"},{"@type":"NRID","@value":"9000021809618"},{"@type":"NRID","@value":"9000253130327"},{"@type":"NRID","@value":"9000254700937"},{"@type":"NRID","@value":"9000020965716"},{"@type":"NRID","@value":"9000254232272"},{"@type":"NRID","@value":"9000240038237"},{"@type":"NRID","@value":"9000257712709"},{"@type":"NRID","@value":"9000243877059"},{"@type":"NRID","@value":"9000254708472"},{"@type":"NRID","@value":"9000256047598"},{"@type":"NRID","@value":"9000413560768"},{"@type":"NRID","@value":"9000253127247"},{"@type":"NRID","@value":"9000021380793"},{"@type":"NRID","@value":"9000253128145"},{"@type":"NRID","@value":"9000257704386"},{"@type":"NRID","@value":"9000254706818"},{"@type":"NRID","@value":"9000257728166"},{"@type":"NRID","@value":"9000254696892"},{"@type":"NRID","@value":"9000257730493"},{"@type":"NRID","@value":"9000256042366"},{"@type":"NRID","@value":"9000256039903"},{"@type":"NRID","@value":"9000006800416"},{"@type":"NRID","@value":"9000256042787"},{"@type":"NRID","@value":"9000020128471"},{"@type":"NRID","@value":"9000022206545"},{"@type":"NRID","@value":"9000252802090"},{"@type":"NRID","@value":"9000256048403"},{"@type":"NRID","@value":"9000020625920"},{"@type":"NRID","@value":"9000020295271"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0037171"}],"foaf:name":[{"@language":"en","@value":"Matsumoto Yoko"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Graduate Course of Applied Chemistry, Kumamoto Institute of Technology"},{"@language":"ja","@value":"Graduate Course of Applied Chemistry, Kumamoto Institute of Technology"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679552777091","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000257712710"}],"foaf:name":[{"@language":"en","@value":"Kato Toshihiro"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"Graduate Course of Applied Chemistry, Kumamoto Institute of Technology"},{"@language":"en","@value":"Graduate Course of Applied Chemistry, Kumamoto Institute of Technology"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679552777092","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000257712711"}],"foaf:name":[{"@language":"en","@value":"Kemura Yoshinori"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"Graduate Course of Applied Chemistry, Kumamoto Institute of Technology"},{"@language":"en","@value":"Graduate Course of Applied Chemistry, Kumamoto Institute of Technology"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679552777090","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000257712712"}],"foaf:name":[{"@language":"en","@value":"Tsuchiya Makoto"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"Graduate Course of Applied Chemistry, Kumamoto Institute of Technology"},{"@language":"en","@value":"Graduate Course of Applied Chemistry, Kumamoto Institute of Technology"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679552777089","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000257712713"}],"foaf:name":[{"@language":"en","@value":"Yamamoto Megumi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Graduate Course of Applied Chemistry, Kumamoto Institute of Technology"},{"@language":"ja","@value":"Graduate Course of Applied Chemistry, Kumamoto Institute of Technology"}]},{"@id":"https://cir.nii.ac.jp/crid/1030003658373533953","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"70099076"},{"@type":"NRID","@value":"1000070099076"},{"@type":"NRID","@value":"9000018887533"},{"@type":"NRID","@value":"9000022208146"},{"@type":"NRID","@value":"9000021806503"},{"@type":"NRID","@value":"9000021803521"},{"@type":"NRID","@value":"9000021809623"},{"@type":"NRID","@value":"9000252800176"},{"@type":"NRID","@value":"9000254444031"},{"@type":"NRID","@value":"9000016805257"},{"@type":"NRID","@value":"9000020965724"},{"@type":"NRID","@value":"9000254232270"},{"@type":"NRID","@value":"9000254443814"},{"@type":"NRID","@value":"9000240038239"},{"@type":"NRID","@value":"9000257712714"},{"@type":"NRID","@value":"9000000542972"},{"@type":"NRID","@value":"9000243877058"},{"@type":"NRID","@value":"9000254708469"},{"@type":"NRID","@value":"9000254698143"},{"@type":"NRID","@value":"9000240037857"},{"@type":"NRID","@value":"9000256047597"},{"@type":"NRID","@value":"9000257733175"},{"@type":"NRID","@value":"9000019991948"},{"@type":"NRID","@value":"9000253127246"},{"@type":"NRID","@value":"9000243879696"},{"@type":"NRID","@value":"9000392639648"},{"@type":"NRID","@value":"9000000210305"},{"@type":"NRID","@value":"9000021380774"},{"@type":"NRID","@value":"9000253128144"},{"@type":"NRID","@value":"9000257704389"},{"@type":"NRID","@value":"9000256052826"},{"@type":"NRID","@value":"9000000553810"},{"@type":"NRID","@value":"9000006390291"},{"@type":"NRID","@value":"9000021432014"},{"@type":"NRID","@value":"9000253531340"},{"@type":"NRID","@value":"9000392640359"},{"@type":"NRID","@value":"9000000547154"},{"@type":"NRID","@value":"9000257728169"},{"@type":"NRID","@value":"9000020957787"},{"@type":"NRID","@value":"9000254696891"},{"@type":"NRID","@value":"9000018353756"},{"@type":"NRID","@value":"9000283849186"},{"@type":"NRID","@value":"9000021515469"},{"@type":"NRID","@value":"9000020978434"},{"@type":"NRID","@value":"9000253121338"},{"@type":"NRID","@value":"9000256042365"},{"@type":"NRID","@value":"9000256039902"},{"@type":"NRID","@value":"9000006800417"},{"@type":"NRID","@value":"9000020625899"},{"@type":"NRID","@value":"9000255705937"},{"@type":"NRID","@value":"9000256042788"},{"@type":"NRID","@value":"9000256039963"},{"@type":"NRID","@value":"9000258671173"},{"@type":"NRID","@value":"9000022206548"},{"@type":"NRID","@value":"9000022207807"},{"@type":"NRID","@value":"9000252802089"},{"@type":"NRID","@value":"9000255709347"},{"@type":"NRID","@value":"9000257704958"},{"@type":"NRID","@value":"9000256048409"},{"@type":"NRID","@value":"9000020625924"},{"@type":"NRID","@value":"9000020295265"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0037194"}],"foaf:name":[{"@language":"en","@value":"Ueoka Ryuichi"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"Graduate Course of Applied Chemistry, Kumamoto Institute of Technology"},{"@language":"en","@value":"Graduate Course of Applied Chemistry, Kumamoto Institute of Technology"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"03667022"},{"@type":"LISSN","@value":"03667022"},{"@type":"EISSN","@value":"13480715"},{"@type":"PISSN","@value":"https://id.crossref.org/issn/03667022"},{"@type":"PISSN","@value":"http://id.crossref.org/issn/03667022"}],"prism:publicationName":[{"@language":"en","@value":"Chemistry Letters"},{"@language":"en","@value":"Chem. Lett."}],"dc:publisher":[{"@language":"en","@value":"The Chemical Society of Japan"},{"@language":"ja","@value":"公益社団法人 日本化学会"}],"prism:publicationDate":"1999","prism:volume":"28","prism:number":"1","prism:startingPage":"53","prism:endingPage":"54"},"reviewed":"false","url":[{"@id":"https://academic.oup.com/chemlett/article-pdf/28/1/53/56077044/cl.1999.53.pdf"}],"availableAt":"1999","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360855570801936896","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Detection of Cell-Affecting Agents with a Silicon Biosensor"}]},{"@id":"https://cir.nii.ac.jp/crid/1362825894112279040","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Membrane matrix for the hydrolysis of amino acid esters with marked enantioselectivity"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204584575744","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Specific Fixed Aqueous Layer of Three-component Hybrid Liposomes Related to Inhibition of Hepatoma Cells Growth"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204589609344","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Inhibitory Effects of Hybrid Liposomes Composed of Phosphatidylcholine and Docosahexaenoic Acid on the Growth of Colon Cancer Cells along with Apoptosis and Differentiation"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204589851776","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Clustering of Lipid Rafts in Plasma Membranes by Hybrid Liposomes for Leukemia Cells along with Apoptosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204623782144","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Specific Hybrid Liposomes Composed of Phosphatidylcholine and Polyoxyethylenealkyl Ether with Markedly Enhanced Inhibitory Effects on the Growth of Tumor Cells In Vitro."}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204626905472","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Specific inhibitory effect of hybrid liposomes on growth of human lymphoma-human lymphocyte b hybridoma cells in vitro."}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679139637120","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Effect of flavonoids in hybrid membranes on the activity of tripeptide as an enzyme model and their inhibition of hybridoma growth in vitro."},{"@value":"Effects of flavonoids in hybrid membranes on the activity of tripeptide as an enzyme model and their inhibition of hybridoma growth in vitro"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679140046080","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Remarkably Enhanced Inhibitory Effects of Three-Component Hybrid Liposomes Including Sugar Surfactants on the Growth of Lung Carcinoma Cells."}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679545930496","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Induction of Apoptosis by Hybrid Liposomes without Antitumor Drugs toward Human Breast Tumor Cells"},{"@value":"Induction of Apoptosis by Hybrid Liposomes without Antitumor Drugs toward Human Breast Tumor Cells(SC)"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679618919680","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Chemotherapy with hybrid liposomes for cancer: An experimental study."},{"@value":"担癌モデルマウスに対するハイブリッド型リポソームの治療効果"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282681105361792","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"抗がん剤を含まないハイブリッド型リポソームのみによる<i>in Vivo</i> でのがん化学療法"},{"@language":"en","@value":"Chemotherapy with Hybrid Liposomes without Any Drug <i>in Vivo</i>"},{"@value":"抗がん剤を含まないハイブリッド型リポソームのみによるin Vivoでのがん化学療法"},{"@language":"ja-Kana","@value":"コウガンザイ オ フクマナイ ハイブリッドガタ リポソーム ノミ ニ ヨル in Vivo デ ノ ガン カガク リョウホウ"},{"@value":"Chemotherapy with hybrid liposomes without any drug in vivo"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282681500473472","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Physical Properties and Inhibitory Effects of Three-component Hybrid Liposomes Including Sugar Surfactants"},{"@language":"ja","@value":"糖含有三成分系ハイブリッドリポソームの物性と制がん効果に関する基礎研究"},{"@language":"ja-Kana","@value":"トウ ガンユウ 3セイブンケイ ハイブリッド リポソーム ノ ブッセイ ト セイガン コウカ ニ カンスル キソ ケンキュウ"}]}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:0008581321"},{"@type":"CROSSREF","@value":"10.1246/cl.1999.53"},{"@type":"CIA","@value":"130004421241"},{"@type":"CROSSREF","@value":"10.1248/cpb.50.563_references_DOI_AhUq7ZnwhbUjiDqKxLZLqIdgwd3"},{"@type":"CROSSREF","@value":"10.1246/cl.2008.118_references_DOI_AhUq7ZnwhbUjiDqKxLZLqIdgwd3"},{"@type":"CROSSREF","@value":"10.1252/jcej.36.1127_references_DOI_AhUq7ZnwhbUjiDqKxLZLqIdgwd3"},{"@type":"CROSSREF","@value":"10.1295/koron.65.90_references_DOI_AhUq7ZnwhbUjiDqKxLZLqIdgwd3"},{"@type":"CROSSREF","@value":"10.1246/cl.2011.90_references_DOI_AhUq7ZnwhbUjiDqKxLZLqIdgwd3"},{"@type":"CROSSREF","@value":"10.1246/cl.2010.1291_references_DOI_AhUq7ZnwhbUjiDqKxLZLqIdgwd3"},{"@type":"CROSSREF","@value":"10.1248/yakushi.123.25_references_DOI_AhUq7ZnwhbUjiDqKxLZLqIdgwd3"}]}