Crosslinking-assisted Stabilization of Beaded Nanofibers from Elastin-like Double Hydrophobic Polypeptides

  • Le Duc H. T.
    Department of Chemical System Engineering, School of Engineering, The University of Tokyo
  • Kawakami Reiko
    Department of Chemical System Engineering, School of Engineering, The University of Tokyo
  • Teraoka Yusuke
    Department of Chemical System Engineering, School of Engineering, The University of Tokyo
  • Okubo Tatsuya
    Department of Chemical System Engineering, School of Engineering, The University of Tokyo
  • Sugawara-Narutaki Ayae
    Department of Crystalline Materials Science, Graduate School of Engineering, Nagoya University

説明

A double hydrophobic elastin-like block polypeptide having crosslinkable amino groups at both termini has been constructed for the first time. Upon an increase in temperature, the block polypeptide assembles into beaded nanofibers in water. The noncrosslinked nanofibers partially dissociate at lower temperatures, while their crosslinked counterparts retain their beaded fiber morphology.

収録刊行物

  • Chemistry Letters

    Chemistry Letters 44 (4), 530-532, 2015

    公益社団法人 日本化学会

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