Perfusion CT is useful for the differential diagnosis of autoimmune pancreatitis from pancreatic cancer

DOI Web Site 29 References
  • HIROTA Morihisa
    Division of Gastroenterology, Tohoku University Graduate School of Medicine
  • TSUJI Yoshihisa
    Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine
  • TSUDA Masashi
    Department of Diagnostic Radiology, Tohoku University Graduate School of Medicine
  • KIKUTA Kazuhiro
    Division of Gastroenterology, Tohoku University Graduate School of Medicine
  • KANNO Atsushi
    Division of Gastroenterology, Tohoku University Graduate School of Medicine
  • MASAMUNE Atsushi
    Division of Gastroenterology, Tohoku University Graduate School of Medicine
  • SHIMOSEGAWA Tooru
    Division of Gastroenterology, Tohoku University Graduate School of Medicine
  • TAKIKAWA Tetsuya
    Division of Gastroenterology, Tohoku University Graduate School of Medicine
  • HAMADA Shin
    Division of Gastroenterology, Tohoku University Graduate School of Medicine
  • KUME Kiyoshi
    Division of Gastroenterology, Tohoku University Graduate School of Medicine
  • CHIBA Tsutomu
    Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine
  • HAYASHI Shintaro
    Division of Gastroenterology, Tohoku University Graduate School of Medicine
  • MIURA Shin
    Division of Gastroenterology, Tohoku University Graduate School of Medicine
  • UNNO Jun
    Division of Gastroenterology, Tohoku University Graduate School of Medicine
  • ARIGA Hiroyuki
    Division of Gastroenterology, Tohoku University Graduate School of Medicine

Bibliographic Information

Other Title
  • 膵血流解析による自己免疫性膵炎と膵癌の鑑別
Published
2012
DOI
  • 10.2958/suizo.27.601
Publisher
Japan Pancreas Society

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Description

Radiological findings of autoimmune pancreatitis (AIP) are sometimes similar to those of pancreatic cancer (PC). The aim of this study was to clarify the utility of perfusion computed tomography (CT) for the differential diagnosis of AIP from PC. Perfusion CT was performed in 12 patients with AIP and 22 patients with PC. All AIP patients were diagnosed as type 1. Parameters including pancreatic volumetric blood flow FV, volume of distribution VD and blood perfusion pattern R2 were determined from a single-compartment kinetic model. Pancreatic FV values of the 12 AIP patients (81.3/min) were significantly higher than those of 22 PC patients (19.3/min, p=0.0005). Pancreatic VD values of the AIP patients (28.8) were significantly lower than those of the PC patients (93.6, p=0.0084). Moreover, pancreatic R2 values of the AIP patients (0.659) were significantly higher than those of the PC patients (0.250, p<0.0001). Perfusion CT is useful to distinguish AIP from PC by the comparison of the parameters of blood flow, distribution and blood perfusion pattern.<br>

Journal

  • Suizo

    Suizo 27 (4), 601-607, 2012

    Japan Pancreas Society

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