{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679656555648.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.4009/jsdt.47.375"}},{"identifier":{"@type":"NDL_BIB_ID","@value":"025624759"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/bib/025624759"}},{"identifier":{"@type":"URI","@value":"https://ndlsearch.ndl.go.jp/books/R000000004-I025624759"}},{"identifier":{"@type":"URI","@value":"https://www.jstage.jst.go.jp/article/jsdt/47/6/47_375/_pdf"}},{"identifier":{"@type":"NAID","@value":"130004542541"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2014277949"}}],"dc:title":[{"@language":"ja","@value":"ポリスルホン膜から溶出するポリビニルピロリドンの紫外光による迅速測定の試み"},{"@language":"en","@value":"Real-time measurement of polyvinylpyrrolidone by ultraviolet spectroscopy"},{"@value":"透析技術 ポリスルホン膜から溶出するポリビニルピロリドンの紫外光による迅速測定の試み"},{"@language":"ja-Kana","@value":"トウセキ ギジュツ ポリスルホンマク カラ トケダスル ポリビニルピロリドン ノ シガイコウ ニ ヨル ジンソク ソクテイ ノ ココロミ"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"Elution of polyvinylpyrrolidone (PVP) from polysulfone (PS) dialysis membrane is one of the most important problems in dialysis therapy. When dialysis treatment is started, rapid measurement of PVP eluted from the PS membrane is desirable. In this study, real-time measurement of PVP using ultraviolet spectroscopy (UV-s method) was compared with the conventional iodine coloration method (Müller method). As a result, there was a significant correlation between the UV-s and Müller methods for measuring PVP concentrations of less than 10 mg/L (r=0.970, p<0.001) and also for concentrations from 10 to 100 mg/L (r=0.993, p<0.001). The PVP concentration in PS-1.6UW dialyzer washings obtained by rinsing with 0.5 L was 2.8±2.9 mg/L by the Müller method and 3.6±2.1 mg/L by the UV-s method, while the PVP concentrations after rinsing with 1.0 L were 2.0±2.1 mg/L and 3.1±0.9 mg/L, respectively. There were no significant differences between the two methods. However, as the PVP concentration accounted for most of the dialyzer washings, the UV-s value for the PVP eluted from a dialyzer is thought to be close to the real value. It is possible to perform real-time measurement of PVP by the UV-s method and PVP eluted from a PS-1.6UW dialyzer can be measured by the UV-s method."},{"@language":"ja","@value":"ポリスルホン (PS) 膜ダイアライザから親水化剤ポリビニルピロリドン (PVP) が溶出することは, 透析療法における問題の一つである. 透析治療を施行するうえでは膜溶出PVPの迅速測定が望ましい. 本研究では, PVPの紫外線スペクトルを用いた簡易的かつ迅速測定法 (UV-s法) を確立すべく, 従来のヨウ素呈色法であるMüller法 (M法) と比較検討した. その結果, PVP溶解液に対して, PVP濃度10mg/L以下ではM法とUV-s法はr=0.970と有意な相関関係があり (p<0.001), 10～100mg/LのPVP濃度でもr=0.993と有意な相関が認められた (p<0.001). また, PS膜ダイアライザPS-1.6UW (n=5) を用いて, 生理食塩液1.0Lによる洗浄開始0.5Lおよび1.0L時点におけるPVP溶出量の比較では, 0.5L洗浄時はM法 : 2.8±2.9mg/L, UV-s法 : 3.6±2.1mg/L, 1.0L洗浄時はM法 : 2.0±2.1mg/L, UV-s法 : 3.1±0.9mg/Lと両測定法の間に差を認めず, UV-s法を用いたPVP測定は可能であった. 以上より, PS膜から溶出するPVPをUV-s法を用いることでM法よりも迅速的に測定できることが示唆された."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410853647637783808","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000258211488"}],"foaf:name":[{"@language":"en","@value":"Shimamoto Yoshimasa"},{"@language":"ja","@value":"島本 佳昌"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Osaka Electro-Communication University"},{"@language":"ja","@value":"大阪電気通信大学"},{"@language":"en","@value":"Yamamoto Clinic"},{"@language":"ja","@value":"山本クリニック"}]},{"@id":"https://cir.nii.ac.jp/crid/1410009222186206976","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000018715202"},{"@type":"NRID","@value":"9000386307488"},{"@type":"NRID","@value":"9000019238801"},{"@type":"NRID","@value":"9000258211489"},{"@type":"NRID","@value":"9000283608353"},{"@type":"KAKEN_RESEARCHERS","@value":"90847675"},{"@type":"NRID","@value":"1000090847675"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/ce_miyata"}],"foaf:name":[{"@language":"ja","@value":"宮田 賢宏"},{"@language":"en","@value":"Miyata Masahiro"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Osaka Electro-Communication University"},{"@language":"ja","@value":"大阪電気通信大学"},{"@language":"en","@value":"Department of Clinical Engineering, Hattori Hospital"},{"@language":"ja","@value":"一陽会服部病院臨床工学室"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679656555649","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000258211490"}],"foaf:name":[{"@language":"ja","@value":"松下 誠吾"},{"@language":"en","@value":"Matsushita Seigo"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Yamamoto Clinic"},{"@language":"ja","@value":"山本クリニック"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679656555652","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000258211491"}],"foaf:name":[{"@language":"ja","@value":"粕本 博臣"},{"@language":"en","@value":"Kasumoto Hiroomi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Dialysis, Kawasaki Hospital"},{"@language":"ja","@value":"川崎病院人工透析室"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204680106253","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000001234939"}],"foaf:name":[{"@language":"ja","@value":"山本 貴敏"},{"@language":"en","@value":"Yamamoto Takatoshi"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"山本クリニック"},{"@language":"en","@value":"Yamamoto Clinic"}]},{"@id":"https://cir.nii.ac.jp/crid/1410853647637783809","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000258211493"}],"foaf:name":[{"@language":"en","@value":"Kamada Aki"},{"@language":"ja","@value":"鎌田 亜紀"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Osaka Electro-Communication University"},{"@language":"ja","@value":"大阪電気通信大学"},{"@language":"en","@value":"Saiseikai Suita Hospital"},{"@language":"ja","@value":"済生会吹田病院"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679656555653","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000258211494"}],"foaf:name":[{"@language":"ja","@value":"海本 浩一"},{"@language":"en","@value":"Umimoto Koichi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Osaka Electro-Communication University"},{"@language":"ja","@value":"大阪電気通信大学"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"13403451"},{"@type":"EISSN","@value":"1883082X"},{"@type":"NDL_BIB_ID","@value":"000000091485"},{"@type":"ISSN","@value":"13403451"},{"@type":"LISSN","@value":"13403451"},{"@type":"NCID","@value":"AN10432053"}],"prism:publicationName":[{"@language":"en","@value":"Nihon Toseki Igakkai Zasshi"},{"@language":"ja","@value":"日本透析医学会雑誌"},{"@language":"en","@value":"Nihon Toseki Igakkai Zasshi"},{"@language":"en","@value":"Journal of Japanese Society for Dialysis Therapy"},{"@language":"en","@value":"J. Jpn. Soc. Dial. Ther."},{"@language":"ja","@value":"透析会誌"}],"dc:publisher":[{"@language":"en","@value":"The Japanese Society for Dialysis Therapy"},{"@language":"ja","@value":"一般社団法人 日本透析医学会"}],"prism:publicationDate":"2014","prism:volume":"47","prism:number":"6","prism:startingPage":"375","prism:endingPage":"379"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"http://id.ndl.go.jp/bib/025624759"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I025624759"},{"@id":"https://www.jstage.jst.go.jp/article/jsdt/47/6/47_375/_pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2014277949"}],"availableAt":"2014","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=%E3%83%9D%E3%83%AA%E3%82%B9%E3%83%AB%E3%83%9B%E3%83%B3%E8%86%9C","dc:title":"ポリスルホン膜"},{"@id":"https://cir.nii.ac.jp/all?q=%E3%83%9D%E3%83%AA%E3%83%93%E3%83%8B%E3%83%AB%E3%83%94%E3%83%AD%E3%83%AA%E3%83%89%E3%83%B3","dc:title":"ポリビニルピロリドン"},{"@id":"https://cir.nii.ac.jp/all?q=%E7%B4%AB%E5%A4%96%E7%B7%9A%E3%82%B9%E3%83%9A%E3%82%AF%E3%83%88%E3%83%AB","dc:title":"紫外線スペクトル"},{"@id":"https://cir.nii.ac.jp/all?q=polysulfone%20membrane","dc:title":"polysulfone membrane"},{"@id":"https://cir.nii.ac.jp/all?q=polyvinylpyrrolidone","dc:title":"polyvinylpyrrolidone"},{"@id":"https://cir.nii.ac.jp/all?q=ultraviolet%20spectrum","dc:title":"ultraviolet spectrum"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360292618877299712","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Effects of fluid flow on elution of hydrophilic modifier from dialysis membrane surfaces"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619298791424","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Excretion and Distribution of Polyvinyl Pyrrolidone in Man: As Determined by Use of Radiocarbon as a Tracer"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855571300411392","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Poly(N-vinyl-2-pyrrolidone) elution from polysulfone dialysis membranes by varying solvent and wall shear stress"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137044511807104","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Anaphylactic reaction induced by a polysulfone/polyvinylpyrrolidone membrane in the 10th session of hemodialysis with the same dialyzer"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981471457581312","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Longer storage of dialyzers increases elution of poly(N-vinyl-2-pyrrolidone) from polysulfone-group dialysis membranes"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262945970472064","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Delayed near-fatal anaphylactic reaction induced by the F10-HPS polysulphone haemodialyser"}]},{"@id":"https://cir.nii.ac.jp/crid/1363388845608477056","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Complement-induced thrombus formation on the surface of poly(N-vinylpyrpolidone)-grafted polyethylene"}]}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:1003673606"},{"@type":"NDL_SEARCH","@value":"oai:ndlsearch.ndl.go.jp:R000000004-I025624759"},{"@type":"CROSSREF","@value":"10.4009/jsdt.47.375"},{"@type":"CIA","@value":"130004542541"},{"@type":"OPENAIRE","@value":"doi_dedup___::068589ba4f01a3108e1df78c829da580"}]}