{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679660569216.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.2482/haigan.54.831"}},{"identifier":{"@type":"URI","@value":"https://www.jstage.jst.go.jp/article/haigan/54/6/54_831/_pdf"}},{"identifier":{"@type":"NAID","@value":"130004705039"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2015348203"}}],"dc:title":[{"@language":"ja","@value":"気管支鏡診断―自家蛍光気管支鏡を中心に―"},{"@language":"en","@value":"Diagnosis by Bronchoscopy -Focusing on Autofluorescence Bronchoscopy-"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"<b><i>Objective. </i></b>As endoscopic treatment is extensively employed to treat central type early-stage lung cancers, the ability to detect such lesions is becoming more important. However, diagnosing flat type lesions using conventional bronchoscopy is difficult in cases involving subtle mucosal changes. Therefore, improving the rate of detection of intraepithelial lesions is clinically desirable. <b><i>Methods. </i></b>The clinical usefulness of autofluorescence bronchoscopy (AFB) was evaluated by reviewing previous reports and the authors' experience. <b><i>Results. </i></b>There were no significant differences in the sensitivity of detecting invasive cancers between conventional bronchoscopy and AFB. However, AFB demonstrated higher sensitivity in cases of early cancer and atypical squamous cell lesions, which may contribute to improving the diagnosis. Mucosal invasion was clearly observed on AFB, which may provide useful support for endoscopic treatment. <b><i>Conclusions. </i></b>The combined use of conventional bronchoscopy and AFB is recommended for diagnosing and treating central type early-stage lung cancer."},{"@language":"ja","@value":"<b>目的．</b>中心型早期肺癌の多くに気管支鏡的治療が適応されるようになり，その診断が一層重要になってきた．しかし平坦型の症例で粘膜の変化が軽微な場合は，通常の気管支鏡で発見が困難なことが多い．これらの病変をより早期に診断することが臨床的に望まれている．<b>方法．</b>自家蛍光気管支鏡（AFB）の気管支早期病変に対する臨床上の有用性を，過去に報告された研究と自験例を用いて評価した．<b>結果．</b>中心型肺癌のうち，進行癌に対しては通常の気管支鏡とAFBでは感度の差がないと考えられる．一方，早期癌および異型扁平上皮などの病変に関しては，AFBは高い感度を示し，診断率の向上に寄与すると認識される．同時に病変の粘膜浸潤範囲の把握も容易であり，気管支鏡的治療の際の支援になることが示唆された．<b>結論．</b>中心型肺癌の診断と治療に際しては，通常の気管支鏡にAFBを併用することが有用である．"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1420001326231523200","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"40317847"},{"@type":"NRID","@value":"1000040317847"},{"@type":"NRID","@value":"9000107385759"},{"@type":"NRID","@value":"9000004672572"},{"@type":"NRID","@value":"9000254179680"},{"@type":"NRID","@value":"9000415049203"},{"@type":"NRID","@value":"9000405884075"},{"@type":"NRID","@value":"9000347091295"},{"@type":"NRID","@value":"9000397866100"},{"@type":"NRID","@value":"9000397866009"},{"@type":"NRID","@value":"9000257921759"},{"@type":"NRID","@value":"9000000692627"},{"@type":"NRID","@value":"9000414490937"},{"@type":"NRID","@value":"9000397972548"},{"@type":"NRID","@value":"9000253625749"},{"@type":"NRID","@value":"9000254179326"},{"@type":"NRID","@value":"9000397840942"},{"@type":"NRID","@value":"9000399378069"},{"@type":"NRID","@value":"9000257920193"},{"@type":"NRID","@value":"9000272994464"},{"@type":"NRID","@value":"9000411586101"},{"@type":"NRID","@value":"9000253623052"},{"@type":"NRID","@value":"9000258290847"},{"@type":"NRID","@value":"9000356886186"},{"@type":"NRID","@value":"9000288816502"},{"@type":"NRID","@value":"9000392015928"},{"@type":"NRID","@value":"9000020685615"},{"@type":"NRID","@value":"9000402897334"},{"@type":"NRID","@value":"9000398395571"},{"@type":"NRID","@value":"9000014265864"},{"@type":"NRID","@value":"9000379606497"},{"@type":"NRID","@value":"9000398279059"},{"@type":"NRID","@value":"9000257919661"},{"@type":"NRID","@value":"9000257918581"},{"@type":"NRID","@value":"9000257922255"},{"@type":"NRID","@value":"9000413513646"},{"@type":"NRID","@value":"9000388534288"},{"@type":"NRID","@value":"9000253617318"},{"@type":"NRID","@value":"9000257919185"},{"@type":"NRID","@value":"9000021936109"},{"@type":"NRID","@value":"9000410651913"},{"@type":"NRID","@value":"9000347090934"},{"@type":"NRID","@value":"9000399374163"},{"@type":"NRID","@value":"9000377379115"},{"@type":"NRID","@value":"9000004682927"},{"@type":"NRID","@value":"9000240164596"},{"@type":"NRID","@value":"9000257918378"},{"@type":"NRID","@value":"9000020307265"},{"@type":"NRID","@value":"9000399375410"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0055800"}],"foaf:name":[{"@language":"ja","@value":"大平 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徳彦"},{"@language":"en","@value":"Ikeda Norihiko"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Surgery, Tokyo Medical University"},{"@language":"ja","@value":"東京医科大学呼吸器・甲状腺外科学分野"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"03869628"},{"@type":"LISSN","@value":"03869628"},{"@type":"EISSN","@value":"13489992"}],"prism:publicationName":[{"@language":"en","@value":"Haigan"},{"@language":"ja","@value":"肺癌"},{"@language":"en","@value":"JJLC"},{"@language":"en","@value":"Japanese Journal of Lung Cancer"},{"@language":"ja","@value":"肺癌"},{"@language":"en","@value":"Haigan"}],"dc:publisher":[{"@language":"en","@value":"The Japan Lung Cancer Society"},{"@language":"ja","@value":"特定非営利活動法人 日本肺癌学会"}],"prism:publicationDate":"2014","prism:volume":"54","prism:number":"6","prism:startingPage":"831","prism:endingPage":"834"},"reviewed":"false","url":[{"@id":"https://www.jstage.jst.go.jp/article/haigan/54/6/54_831/_pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2015348203"}],"availableAt":"2014","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=%E8%82%BA%E7%99%8C","dc:title":"肺癌"},{"@id":"https://cir.nii.ac.jp/all?q=%E8%87%AA%E5%AE%B6%E8%9B%8D%E5%85%89%E6%B0%97%E7%AE%A1%E6%94%AF%E9%8F%A1","dc:title":"自家蛍光気管支鏡"},{"@id":"https://cir.nii.ac.jp/all?q=%E4%B8%AD%E5%BF%83%E5%9E%8B%E6%97%A9%E6%9C%9F%E8%82%BA%E7%99%8C","dc:title":"中心型早期肺癌"},{"@id":"https://cir.nii.ac.jp/all?q=%E7%95%B0%E5%9E%8B%E6%89%81%E5%B9%B3%E4%B8%8A%E7%9A%AE","dc:title":"異型扁平上皮"},{"@id":"https://cir.nii.ac.jp/all?q=Lung%20cancer","dc:title":"Lung cancer"},{"@id":"https://cir.nii.ac.jp/all?q=Autofluorescence%20bronchoscopy","dc:title":"Autofluorescence bronchoscopy"},{"@id":"https://cir.nii.ac.jp/all?q=Central%20type%20early-stage%20lung%20cancer","dc:title":"Central type early-stage lung cancer"},{"@id":"https://cir.nii.ac.jp/all?q=Atypical%20squamous%20cell","dc:title":"Atypical squamous cell"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360002214608319104","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"New aspects of photodynamic therapy for central type early stage lung cancer"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619596654976","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Endoscopic criteria of early squamous cell carcinoma of the bronchus"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619979015296","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Detection and Localization of Intraepithelial Neoplasia and Invasive Carcinoma Using Fluorescence-Reflectance Bronchoscopy: 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