{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679718928384.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.18907/jjsre.14.1_15"}},{"identifier":{"@type":"NAID","@value":"110002817313"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/1992218019"}}],"dc:title":[{"@language":"ja","@value":"非ホジキンリンパ腫の気管支内病変 : 分類と病態"},{"@language":"en","@value":"Classification and Clinical Features of Endobronchial Involvement of Non-Hodgkin's Lymphoma"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"Three cases of endobronchial involvement of non-Hodgkin's lymphoma were experienced. To the best of our knowledge, there have been 37 reported cases of endobronchial involvement of non-Hodgkin's lymphoma identified by bronchoscopic examination. These and our own cases were endoscopically classified into 3 types and investigated. Type I ; Elevated tumor mass was found in 19 cases. 11 of which were recurrent disease. This type was characterized by the radiological findings of a hilar mass or atelectasis. Type II ; Multiple submucosal nodules were found in 12 cases All of them were in patients with advanced disease (stage IV), and the radiological findings of parenchymal infiltration were frequently seen in this type. Type III ; Diffuse submucosal infiltration was found in 9 cases. The radiological findings of this type were similar to those of type I, however, 6 cases were initial disease, and their courses were worse than those of type I. In 29 of 40 cases in which data in available, long-term survival was obtained with combined radiotherapy and chemotherapy. Although it has been thought that endobronchial involvement of non-Hodgkin's lymphoma was associated with disseminated disease and was less common than of Hodgkin's disease, it may not be as rare as had been thought. In patients with non-Hodgkin's lymphoma, radiological findings of a hilar mass, atelectasis or parenchymal infiltration may indicate endobronchial involvement. It is important to clarify the frequency of endobronchial involvement and to evaluate the implication for staging, therapy and prognosis. If confirmed by further investigation, bronchoscopic findings may be contributory to evaluation of the prognosis of patients with intrathoracic non-Hodgkin's lymphoma."},{"@language":"ja","@value":"気管支内病変(EBI)を認めた非ホジキンリンパ腫(NHL)の3例を経験した。NHLのEBIは現在まで内外合わせて37例の報告があるのみで, 自験例を含め, 気管支鏡所見を3型に分類して検討した。隆起性腫瘤病変は, 再発例に多く, 胸部X線上肺門縦隔リンパ節腫大あるいは無気肺がみられ, 粘膜下腫瘍との鑑別が必要であった。また, 初発例では長期生存例が多くみられた。多発性粘膜下小結節病変は, 胸部X線所見は浸潤影を呈し, 初発例に多いが, 全例がstage IVで予後不良であった。びまん性粘膜下浸潤病変は, 初発例に多く, 胸部X線所見は隆起性腫瘤状病変に類似するが, 初発例に短期死亡例が多くみられた。治療法は, 切除手術を施行した例および化学療法に放射線療法を併用した例に長期生存例が多くみられた。胸郭内病変を呈するNHLに積極的に気管支鏡を施行することにより, EBIの有無とその所見の解析から予後を推定できる可能性がある。"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410282679718928392","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"谷川 恵"},{"@language":"en","@value":"Tanigawa Satoshi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The First Department of Internal Medicine, Nihon University School of Medicine"},{"@language":"ja","@value":"日本大学医学部第1内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679718928386","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"細川 芳文"},{"@language":"en","@value":"Hosokawa Yoshifumi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The First Department of Internal Medicine, Nihon University School of Medicine"},{"@language":"ja","@value":"日本大学医学部第1内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679718928390","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"安部 幹夫"},{"@language":"en","@value":"Abe Mikio"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The First Department of Internal Medicine, Nihon University School of Medicine"},{"@language":"ja","@value":"日本大学医学部第1内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679718928394","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"弘田 達哉"},{"@language":"en","@value":"Hirota Tatsuya"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The First Department of Internal Medicine, Nihon University School of Medicine"},{"@language":"ja","@value":"日本大学医学部第1内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679718928384","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"本橋 雅昭"},{"@language":"en","@value":"Motohashi Masaaki"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The First Department of Internal Medicine, Nihon University School of Medicine"},{"@language":"ja","@value":"日本大学医学部第1内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679718928388","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"大嶋 康"},{"@language":"en","@value":"Ooshima Kou"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The First Department of Internal Medicine, Nihon University School of Medicine"},{"@language":"ja","@value":"日本大学医学部第1内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679718928393","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"高橋 典明"},{"@language":"en","@value":"Takahashi Noriaki"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The First Department of Internal Medicine, Nihon University School of Medicine"},{"@language":"ja","@value":"日本大学医学部第1内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679718928391","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"木下 靖"},{"@language":"en","@value":"Kinoshita Yasushi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The First Department of Internal Medicine, Nihon University School of Medicine"},{"@language":"ja","@value":"日本大学医学部第1内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679718928385","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"吉信 尚"},{"@language":"en","@value":"Yoshinobu Takashi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The First Department of Internal Medicine, Nihon University School of Medicine"},{"@language":"ja","@value":"日本大学医学部第1内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679718928387","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"升谷 雅行"},{"@language":"en","@value":"Masutani Masayuki"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The First Department of Internal Medicine, Nihon University School of Medicine"},{"@language":"ja","@value":"日本大学医学部第1内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1030566608436872962","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"60090081"},{"@type":"NRID","@value":"1000060090081"},{"@type":"NRID","@value":"9000020617298"},{"@type":"NRID","@value":"9000020426549"},{"@type":"NRID","@value":"9000020578480"},{"@type":"NRID","@value":"9000253596109"},{"@type":"NRID","@value":"9000014427330"},{"@type":"NRID","@value":"9000004439396"},{"@type":"NRID","@value":"9000020484236"},{"@type":"NRID","@value":"9000020576148"},{"@type":"NRID","@value":"9000253580962"},{"@type":"NRID","@value":"9000363250133"},{"@type":"NRID","@value":"9000020542522"},{"@type":"NRID","@value":"9000255938851"},{"@type":"NRID","@value":"9000007683851"},{"@type":"NRID","@value":"9000253582702"},{"@type":"NRID","@value":"9000252903571"},{"@type":"NRID","@value":"9000258042712"},{"@type":"NRID","@value":"9000020527302"},{"@type":"NRID","@value":"9000020485072"},{"@type":"NRID","@value":"9000020579574"},{"@type":"NRID","@value":"9000253590947"},{"@type":"NRID","@value":"9000253629822"},{"@type":"NRID","@value":"9000253609857"},{"@type":"NRID","@value":"9000253563077"},{"@type":"NRID","@value":"9000254623579"},{"@type":"NRID","@value":"9000253616595"},{"@type":"NRID","@value":"9000253565284"},{"@type":"NRID","@value":"9000253565235"},{"@type":"NRID","@value":"9000258040360"},{"@type":"NRID","@value":"9000253595984"},{"@type":"NRID","@value":"9000256816938"},{"@type":"NRID","@value":"9000253600957"},{"@type":"NRID","@value":"9000253580536"},{"@type":"NRID","@value":"9000252899195"},{"@type":"NRID","@value":"9000253560137"},{"@type":"NRID","@value":"9000021011198"},{"@type":"NRID","@value":"9000020726495"},{"@type":"NRID","@value":"9000008349792"},{"@type":"NRID","@value":"9000005918765"},{"@type":"NRID","@value":"9000003757298"},{"@type":"NRID","@value":"9000020514766"},{"@type":"NRID","@value":"9000253562608"}],"foaf:name":[{"@language":"ja","@value":"堀江 孝至"},{"@language":"en","@value":"Horie Takashi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The First Department of Internal Medicine, Nihon University School of Medicine"},{"@language":"ja","@value":"日本大学医学部第1内科"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"02872137"},{"@type":"LISSN","@value":"02872137"},{"@type":"EISSN","@value":"21860149"},{"@type":"NCID","@value":"AN00357687"}],"prism:publicationName":[{"@language":"en","@value":"The Journal of the Japan Society for Respiratory Endoscopy"},{"@language":"ja","@value":"気管支学"},{"@language":"en","@value":"J. Jpn. Soc. Respir. Endoscopy"},{"@language":"en","@value":"J. Jpn. Soc. Bronchol."},{"@language":"en","@value":"J. Jpn. Soc. Resp. Endoscopy"},{"@language":"en","@value":"JJSB"},{"@language":"en","@value":"JJSRE"}],"dc:publisher":[{"@language":"en","@value":"The Japan Society for Respiratory Endoscopy"},{"@language":"ja","@value":"日本呼吸器内視鏡学会"}],"prism:publicationDate":"1992","prism:volume":"14","prism:number":"1","prism:startingPage":"15","prism:endingPage":"21"},"url":[{"@id":"https://search.jamas.or.jp/link/ui/1992218019"}],"availableAt":"1992","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=%E6%82%AA%E6%80%A7%E3%83%AA%E3%83%B3%E3%83%91%E8%85%AB","dc:title":"悪性リンパ腫"},{"@id":"https://cir.nii.ac.jp/all?q=%E9%9D%9E%E3%83%9B%E3%82%B8%E3%82%AD%E3%83%B3%E3%83%AA%E3%83%B3%E3%83%91%E8%85%AB","dc:title":"非ホジキンリンパ腫"},{"@id":"https://cir.nii.ac.jp/all?q=%E6%B0%97%E7%AE%A1%E6%94%AF%E5%86%85%E8%85%AB%E7%98%8D","dc:title":"気管支内腫瘍"},{"@id":"https://cir.nii.ac.jp/all?q=%E6%B0%97%E7%AE%A1%E6%94%AF%E9%8F%A1%E6%89%80%E8%A6%8B","dc:title":"気管支鏡所見"},{"@id":"https://cir.nii.ac.jp/all?q=Malignant%20lymphoma","dc:title":"Malignant lymphoma"},{"@id":"https://cir.nii.ac.jp/all?q=Non-Hodgkin's%20lymphoma","dc:title":"Non-Hodgkin's lymphoma"},{"@id":"https://cir.nii.ac.jp/all?q=Endobronchial%20tumor","dc:title":"Endobronchial tumor"},{"@id":"https://cir.nii.ac.jp/all?q=Bronchofiberscopic%20finding","dc:title":"Bronchofiberscopic finding"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1390001204751755392","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"気管支内病変を認めた肺原発Diffuse Large B-cell Lymphomaの1例"},{"@language":"en","@value":"A Case of Primary Pulmonary Diffuse Large B-cell Lymphoma Having a Bronchial Lesion"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204753188736","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"気管支内腔に多発粘膜下結節を認めた肺原発MALTリンパ腫の1例"},{"@language":"en","@value":"A Case of Primary Pulmonary Mucosa-associated Lymphoid Tissue (MALT) Lymphoma Presenting Multiple Endobronchial Submucosal Nodules"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204753936512","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"予想外の気管支粘膜下進展を認めた左上葉原発BALTリンパ腫の1例"},{"@language":"en","@value":"A Case of BALT Lymphoma Occupying the Entire Left Upper Lobe with Unexpected Submucosal Extension to the Left Main Bronchus"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679726759424","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"マイコプラズマ肺炎を契機に発見された気管気管支限局MALTリンパ腫の1例"},{"@language":"en","@value":"A Case of Primary Endobronchial Mucosa-associated Lymphoid Tissue Lymphoma Limited to Endotracheal and Endobronchial Regions, Associated With Mycoplasma pneumoniae"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679728760320","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"気管支内腔所見を認めた,HTLV-1キャリアーのT細胞性非ホジキンリンパ腫の1例"},{"@language":"en","@value":"A Case of T-cell Type, Non-Hodgkin's Lymphoma with Endobronchial Involvement in a Human T-cell Leukemia Virus Type 1 Carrier"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679730038016","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"肺内病変,気管支内病変を認めたホジキンリンパ腫の1例"},{"@language":"en","@value":"A Case of Hodgkin Lymphoma with Pulmonary and Endobronchial Involvement"}]},{"@id":"https://cir.nii.ac.jp/crid/1390305721535185152","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"無気肺の急速な進行と改善を認めた気管支内病変を有する肺悪性リンパ腫の1例"},{"@language":"en","@value":"A case of pulmonary malignant lymphoma with endobronchial involvement with repeated improvement or progress of atelectasis"}]}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:2001351732"},{"@type":"CIA","@value":"110002817313"}]}