Effect of probiotics/synbiotics on patients with criticaly ill patients

DOI Web Site 25 References Open Access
  • Usami Makoto
    Division of Nutrition and Metabolism, Kobe University Graduate School of Health Sciences Department of Nutrition, Kobe University Hospital, Kobe University School of Medicine
  • Miyoshi Makoto
    Division of Nutrition and Metabolism, Kobe University Graduate School of Health Sciences
  • Yamamoto Masashi
    Department of Nutrition, Kobe University Hospital, Kobe University School of Medicine
  • Maeshige Noriaki
    Division of Nutrition and Metabolism, Kobe University Graduate School of Health Sciences
  • Aoyama-Ishikawa Michiko
    Division of Nutrition and Metabolism, Kobe University Graduate School of Health Sciences
  • Yamashita Hayato
    Division of Nutrition and Metabolism, Kobe University Graduate School of Health Sciences
  • Takahashi Michiko
    Department of Nutrition, Kobe University Hospital, Kobe University School of Medicine

Bibliographic Information

Other Title
  • 重症患者へのprobiotics/synbiotics 投与効果
Published
2016
DOI
  • 10.11638/jssmn.50.2_149
Publisher
JAPANESE SOCIETY for SURGICAL METABOLISM and NUTRITION

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Description

The clinical effects of administration of flora (probiotics), supplied fibers (prebiotics), and their combination (synbiotics) with or without enteral nutrition have been reported in meta-analysis of randomized control for critically ill and postoperative patients. The rate of infectious complication is improved by the probiotics/synbiotics treatment in major trauma and patients after gastroenterological surgery, but not acute severe pancreatitis and IUC critically ill patients. The use of probiotics/synbiotics as potential strategy of nutritional therapy is valuable for maintenance of the gut environment and systemic immunity in patients with severe surgical stress. Future major concerns are selection of probiotic species and prebiotics with their combination, their dosage, and duration of treatment.

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