書誌事項
- タイトル別名
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- Studies on IgA-type antibody in patients with hepatitis A
- Aガタ カンエン ニ オケル IgAガタ コウタイ ノ ドウタイ
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説明
The determination of IgA-type antibody against hepatitis A antigen (IgA-type HA antibody) was carried out in 65 sera from 13 patients with hepatitis A by a modified method using anti-IgA coated beads instead of anti-IgM ones in the HAVAB-M kit (Dainabot Co.). The serum IgA-type HA antibody was already detected within 1 week after the onset of symptoms, with maximum levels being observed at approximately 3 weeks after the onset, and then it decreased gradually. These findings were similar to the changes of IgM-type HA antibody, but IgA-type HA antibody was still detectable at 18 weeks after the onset.<BR>In addition, IgA-type antibody in sera proved to be a dimeric form of serum IgA separated by high speed liquid chromatography.<BR>From these results, it was strongly suggested that the intestinal mucosa could play an important role as a major source of serum IgA-type HA antibody at the early stage of HA virus infection.
収録刊行物
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- 肝臓
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肝臓 23 (1), 9-14, 1982
一般社団法人 日本肝臓学会
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詳細情報 詳細情報について
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- CRID
- 1390282679768176000
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- NII論文ID
- 130000877887
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- NII書誌ID
- AN00047770
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- ISSN
- 18813593
- 04514203
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- NDL書誌ID
- 2480115
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可