{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679768816896.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.2957/kanzo.46.78"}},{"identifier":{"@type":"NDL_BIB_ID","@value":"7279565"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/bib/7279565"}},{"identifier":{"@type":"URI","@value":"https://ndlsearch.ndl.go.jp/books/R000000004-I7279565"}},{"identifier":{"@type":"URI","@value":"http://www.jstage.jst.go.jp/article/kanzo/46/2/46_2_78/_pdf"}},{"identifier":{"@type":"NAID","@value":"10015446106"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2005155096"}}],"dc:title":[{"@language":"en","@value":"Spontaneous regression of hepatocellular carcinoma in S4 after another tumor in S1 was chemoembolized"},{"@language":"ja","@value":"多発性肝癌治療経過中に肝細胞癌の完全壊死を認めた１例"},{"@value":"症例報告 多発性肝癌治療経過中に肝細胞癌の完全壊死を認めた1例"},{"@language":"ja-Kana","@value":"ショウレイ ホウコク タハツセイ カンガン チリョウ ケイカ チュウ ニ カン サイボウガン ノ カンゼン エシ オ ミトメタ 1レイ"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"An HCV-infected 77 year-old female with a history of blood transfusion when operated for disk herniation in 1960 developed multiple hepatocellular carcinoma in 2003: one in S1 and another in S4. Considering the impaired function of her cirrhotic liver, we planned to undertake transarterial chemoembolization (TAE) first for only the S1 tumor and later for the S4 tumor. One day, about 4 weeks after TAE was done successfully for her S1 tumor, she suddenly suffered from high fever and a sharp increase in transaminases. On the following day, we performed dynamic CT scanning and found that the S4 tumor had lost its tumor-specific enhancement, suggesting an extensive spontaneous necrosis of this tumor. The S4 tumor continued to regress thereafter. This was a rare event with almost no report in literature to our knowledge, particularly in that we could trace the time course of tumor-regression."},{"@language":"ja","@value":"77歳の女性. 腰部椎間板ヘルニアの際に輸血歴があり, 1992年にC型肝炎ウイルス (HCV) 抗体陽性を指摘された. その後肝硬変に進展し外来経過観察中, 肝S1, S4の多発肝細胞癌 (HCC) を発症し, 加療目的で入院となった. 肝予備能の低下があり2つの腫瘍に対し2期的にTAEを予定した. S1の腫瘤に対してのTAEを施行した後, 3週間ほどの経過を経た時点で発熱及び肝逸脱酵素の急上昇を認めた. 翌日の腹部ダイナミックCTではS4の腫瘤に造影効果を認めなくなっており, HCCの広範壊死と診断した. HCCの広範な自然壊死を経時的に捕らえた報告は稀であり, 大変貴重な症例と考えられた."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410572172269819648","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000001459194"}],"foaf:name":[{"@language":"en","@value":"TAKAYAMA Tetsuro"},{"@language":"ja","@value":"高山 哲朗"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Internal Medicine, School of Medicine, Keio University"},{"@language":"ja","@value":"慶應義塾大学消化器内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410009222380831874","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000000342822"}],"foaf:name":[{"@language":"en","@value":"TADA Shinichiro"},{"@language":"ja","@value":"多田 慎一郎"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Internal Medicine, School of Medicine, Keio University"},{"@language":"ja","@value":"慶應義塾大学消化器内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290696505030912","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000363349044"}],"foaf:name":[{"@language":"en","@value":"YOSHIZAWA Shigeo"},{"@language":"ja","@value":"芳沢 茂雄"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Internal Medicine, School of Medicine, Keio University"},{"@language":"ja","@value":"慶應義塾大学消化器内科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204795662343","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000018670531"},{"@type":"NRID","@value":"9000256798384"}],"foaf:name":[{"@language":"en","@value":"SAITO Hidetsugu"},{"@language":"ja","@value":"斎藤 英胤"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"慶應義塾大学消化器内科"},{"@language":"en","@value":"Department of Internal Medicine, School of Medicine, Keio University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410572172269819651","@type":"Researcher","foaf:name":[{"@language":"en","@value":"HIBI Toshifumi"},{"@language":"ja","@value":"日比 紀文"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Internal Medicine, School of Medicine, Keio University"},{"@language":"ja","@value":"慶應義塾大学消化器内科"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"04514203"},{"@type":"LISSN","@value":"04514203"},{"@type":"EISSN","@value":"18813593"},{"@type":"NDL_BIB_ID","@value":"000000004453"},{"@type":"ISSN","@value":"04514203"},{"@type":"NCID","@value":"AN00047770"}],"prism:publicationName":[{"@language":"en","@value":"Kanzo"},{"@language":"ja","@value":"肝臓"},{"@language":"en","@value":"Kanzo"},{"@language":"ja","@value":"肝臓"},{"@language":"en","@value":"Acta hepatologica Japonica"}],"dc:publisher":[{"@language":"en","@value":"The Japan Society of Hepatology"},{"@language":"ja","@value":"一般社団法人　日本肝臓学会"}],"prism:publicationDate":"2005","prism:volume":"46","prism:number":"2","prism:startingPage":"78","prism:endingPage":"84"},"reviewed":"false","url":[{"@id":"http://id.ndl.go.jp/bib/7279565"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I7279565"},{"@id":"http://www.jstage.jst.go.jp/article/kanzo/46/2/46_2_78/_pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2005155096"}],"availableAt":"2005","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=%E8%82%9D%E7%B4%B0%E8%83%9E%E7%99%8C","dc:title":"肝細胞癌"},{"@id":"https://cir.nii.ac.jp/all?q=%E8%87%AA%E7%84%B6%E5%A3%8A%E6%AD%BB","dc:title":"自然壊死"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360292621082028032","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Spontaneous regression of hepatocellular 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