{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679813995648.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.14930/jsma1939.40.375"}},{"identifier":{"@type":"NDL_BIB_ID","@value":"2336610"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/bib/2336610"}},{"identifier":{"@type":"URI","@value":"https://ndlsearch.ndl.go.jp/books/R000000004-I2336610"}},{"identifier":{"@type":"NAID","@value":"130001824280"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/1981180314"}}],"dc:title":[{"@language":"en","@value":"A CASE OF GARDNER SYNDROME"},{"@language":"ja","@value":"Gardner症候群の1例"},{"@language":"ja-Kana","@value":"Gardner ショウコウグン ノ 1レイ"}],"description":[{"type":"abstract","notation":[{"@language":"en","@value":"Gardner's syndrome (a familial disease, characterized by colonic polyposis, osteoma and soft tissue tumor) was categorized by Gardner (1950) . To the best of our knowlage, 14 cases of this disease were reported in Japan. A case of 28-year-old man of Gardner's syndrome was presented. He was admitted with complaints of gastric discomfort, abdominal pain and diarrhea. Gastrointestinal endoscopiy and X-ray examination showed colonic polyposis, gastric polyposis and osteosclerotic change of the right mandibles bone, no tumor was found in soft tissue. Total resection of the colon was performed. Colectomized specimen showed ulcerated lesions in transvers colon and diffuse polyposis. It was demonstrated that the ulcerated lesions was adenocarcinoma and diffuse polyposis were adenomatous polyp, histologically differentiation of Gardner's syndrome from familial polyposis coli was discussed."},{"@language":"ja","@value":"症例は27歳の男子で, 腹痛, 下痢, 胃部不快感を主訴として来院, 消化管X線検査, 消化管内視鏡検査, 全身骨X線検査から胃ポリポージス, 大腸ポリポージス, 下顎骨の石灰化を認め, 軟部腫瘍の病変を欠く不完全型ガードナー症候群と診断した.生検組織像は胃ポリープは腸上皮化生, 大腸ポリープは腺腫であった.以上から, 大腸全摘出術を施行, 術前には診断できなかった潰瘍性病変を横行結腸に認め, この部位に高分化型腺癌を認めた.ガードナー症候群の三主徴は, 消化管ポリーポジス, 骨腫, 軟部腫瘍で, 1950年ガードナーらにより体系づけられた.常染色体優性遺伝形式をとり, 高率に大腸癌を合併する疾患とされている.本邦でも10数例と報告例も少なく, また, 家族性大腸ポリポージスとの異同もあり, 大変興味ある症例であるので, 文献的考察を加え報告する."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410290696039251459","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000020935697"}],"foaf:name":[{"@language":"en","@value":"OKUMURA Kunihiko"},{"@language":"ja","@value":"奥村 邦彦"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The Second Department of Internal Medicine, School of Medicine, Showa University"},{"@language":"ja","@value":"昭和大学医学部第二内科学教室"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290696039251458","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000020935702"}],"foaf:name":[{"@language":"en","@value":"KODAMA Hidebumi"},{"@language":"ja","@value":"児玉 秀文"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The Second Department of Internal Medicine, School of Medicine, Showa University"},{"@language":"ja","@value":"昭和大学医学部第二内科学教室"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290696039251463","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000020935708"}],"foaf:name":[{"@language":"en","@value":"TANAKA Nobuo"},{"@language":"ja","@value":"田中 宣男"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The Second Department of Internal Medicine, School of Medicine, Showa University"},{"@language":"ja","@value":"昭和大学医学部第二内科学教室"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290696039251460","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000020935710"}],"foaf:name":[{"@language":"en","@value":"TAKEUCHI Haruo"},{"@language":"ja","@value":"竹内 治男"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The Second Department of Internal Medicine, School of Medicine, Showa University"},{"@language":"ja","@value":"昭和大学医学部第二内科学教室"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290696039251462","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000020935715"}],"foaf:name":[{"@language":"en","@value":"NAKAHAMA Makoto"},{"@language":"ja","@value":"中浜 誠"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The Second Department of Internal Medicine, School of Medicine, Showa University"},{"@language":"ja","@value":"昭和大学医学部第二内科学教室"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290696039251457","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000020935722"}],"foaf:name":[{"@language":"en","@value":"SAITO Hirobumi"},{"@language":"ja","@value":"斉藤 博文"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"昭和大学医学部第二内科学教室"},{"@language":"en","@value":"The Second Department of Internal Medicine, School of Medicine, Showa University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290696039251464","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000020935724"}],"foaf:name":[{"@language":"en","@value":"HATTA Yoshio"},{"@language":"ja","@value":"八田 善夫"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"昭和大学医学部第二内科学教室"},{"@language":"en","@value":"The Second Department of Internal Medicine, School of Medicine, Showa University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290696039251456","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000020935730"}],"foaf:name":[{"@language":"en","@value":"MOROHOSHI Toshio"},{"@language":"ja","@value":"諸星 利男"}],"jpcoar:affiliationName":[{"@language":"en","@value":"The First Department of Pathology, School of Medicine, Showa University"},{"@language":"ja","@value":"昭和大学第一病理学教室"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290696039251461","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000020935734"}],"foaf:name":[{"@language":"en","@value":"IREI Masatake"},{"@language":"ja","@value":"伊礼 正剛"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of stomach and intestine, Keihin all-round hospital"},{"@language":"ja","@value":"京浜総合病院胃腸科"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00374342"},{"@type":"EISSN","@value":"21850976"},{"@type":"NDL_BIB_ID","@value":"000000011560"},{"@type":"ISSN","@value":"00374342"},{"@type":"LISSN","@value":"00374342"},{"@type":"NCID","@value":"AN00117027"}],"prism:publicationName":[{"@language":"en","@value":"Journal of The Showa Medical Association"},{"@language":"ja","@value":"昭和医学会雑誌"},{"@language":"en","@value":"J Showa Med Assoc"},{"@language":"en","@value":"J. Showa. Med. Assoc."},{"@language":"ja","@value":"昭医会誌"},{"@language":"ja","@value":"昭和医会誌"}],"dc:publisher":[{"@language":"en","@value":"The Showa University Society"},{"@language":"ja","@value":"昭和大学学士会"}],"prism:publicationDate":"1980","prism:volume":"40","prism:number":"3","prism:startingPage":"375","prism:endingPage":"380"},"url":[{"@id":"http://id.ndl.go.jp/bib/2336610"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I2336610"},{"@id":"https://search.jamas.or.jp/link/ui/1981180314"}],"availableAt":"1980","dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:0036785087"},{"@type":"NDL_SEARCH","@value":"oai:ndlsearch.ndl.go.jp:R000000004-I2336610"},{"@type":"CIA","@value":"130001824280"}]}