{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679825252992.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.3919/jjsa.68.654"}},{"identifier":{"@type":"URI","@value":"http://www.jstage.jst.go.jp/article/jjsa/68/3/68_3_654/_pdf"}},{"identifier":{"@type":"NAID","@value":"130004516493"}},{"identifier":{"@type":"NAID","@value":"10019502992"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2007294964"}}],"dc:title":[{"@language":"en","@value":"A CASE OF A CYSTIC TUMOR OF THE LIVER WITH CANCEROUS CHANGE PRESUMABLY ARISEN FROM A HEPATIC CYST DURING THE SIX FOLLOW-UP YEARS"},{"@language":"ja","@value":"６年間経過観察中に肝嚢胞が癌化したと考えられる肝嚢胞性腫瘍の１例"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"We report a case of a cystic tumor of the liver with cancerous change presumably arisen from a hepatic cyst of the caudate lobe that had been followed for about six years. A 76-year-old male who had been followed for a hepatic cyst elsewhere since 1996 was referred to our hospital in January 2003 because abdominal CT scan demonstrated a solid component within the hepatic cyst. Abdominal CT scan showed a solid component within a 4.5-cm cyst in the caudate lobe of the liver. Endoscopic retrograde cholangiography showed communication between the duct in the left hepatic lobe and the cystic lesion. Fine -needle aspiration of the cystic lesion was conducted under ultrasonography and the cytological diagnosis was class V. An extended left lobectomy with caudate lobectomy was performed under a diagnosis of cystic tumor with cancerous change arisen from a hepatic cyst. On gross examination of the resected specimen, a 2-cm solid projection was present in a 5.2-cm cystic lesion. Pathologically high columnar atypical epithelial cells proliferated in a papillary form in the cystic wall and the solid component was composed of well differentiated adenocarcimoma. The patient is alive bearing multiple liver metastases and para-aortic lymph node metastasis 3 years and 1 month after the surgery.<br>It is very important to detect every small change in hepatic cysts early by abdominal ultrasonography and CT scan, because the hepatic cystic have a potential to degenerate into cystic tumor with cancerous change."},{"@language":"ja","@value":"肝尾状葉の単純性嚢胞で6年間の経過観察中に肝嚢胞が癌化したと考えられる肝嚢胞性腫瘍の1例を経験したので報告する. 症例は76歳, 男性. 1996年より肝嚢胞を近医で経過観察中, 2003年1月腹部CTで嚢胞内に隆起性病変を認められ当科に紹介となった. 腹部CTで肝尾状葉に4.5cm大の嚢胞性病変の内部に充実性部分を認めた. ERCPでは肝左葉内の胆管と嚢胞との間に交通を認めた. 超音波ガイド下の嚢胞の穿刺細胞診ではclass Vであった. 肝嚢胞の癌化の診断で拡大肝左葉切除, 尾状葉切除を行った. 摘出標本では5.2cm大の嚢胞性病変の内部に2cm大の充実性腫瘍を認めた. 病理組織検査では嚢胞壁には異型高円柱上皮が乳頭状に増生しており, 充実成分は高分化腺癌であった. 術後3年1カ月の現在, 多発肝転移, 大動脈周囲リンパ節転移を認めるが生存中である. 単純性肝嚢胞を経過観察する場合, 肝嚢胞が癌化する可能性を念頭に置き, 腹部超音波, 腹部CTなどにより嚢胞の形態変化を早期に発見することが重要と思われた."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410290697322529153","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000258105122"}],"foaf:name":[{"@language":"en","@value":"UDAKA Tetsunobu"},{"@language":"ja","@value":"宇高 徹総"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Surgery, Mitoyo General Hospital"},{"@language":"ja","@value":"三豊総合病院外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290697322529154","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000258105124"}],"foaf:name":[{"@language":"en","@value":"KUBO Masatoshi"},{"@language":"ja","@value":"久保 雅俊"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Surgery, Mitoyo General Hospital"},{"@language":"ja","@value":"三豊総合病院外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290697322529155","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000258105123"},{"@type":"NRID","@value":"9000006450561"}],"foaf:name":[{"@language":"en","@value":"WAKI Naohisa"},{"@language":"ja","@value":"脇 直久"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Surgery, Mitoyo General Hospital"},{"@language":"ja","@value":"三豊総合病院外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290697322529025","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000258105125"},{"@type":"NRID","@value":"9000241509402"}],"foaf:name":[{"@language":"en","@value":"MIZUTA Minoru"},{"@language":"ja","@value":"水田 稔"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Surgery, Mitoyo General Hospital"},{"@language":"ja","@value":"三豊総合病院外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290697322529024","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000258105126"},{"@type":"NRID","@value":"9000241509404"}],"foaf:name":[{"@language":"en","@value":"SHIRAKAWA Kazutoyo"},{"@language":"ja","@value":"白川 和豊"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Surgery, Mitoyo General Hospital"},{"@language":"ja","@value":"三豊総合病院外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410290697322529152","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000258105127"},{"@type":"NRID","@value":"9000002829898"}],"foaf:name":[{"@language":"en","@value":"MIYATANI Katsuya"},{"@language":"ja","@value":"宮谷 克也"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Pathology, Mitoyo General Hospital"},{"@language":"ja","@value":"三豊総合病院病理"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"13452843"},{"@type":"EISSN","@value":"18825133"},{"@type":"NCID","@value":"AA11189709"}],"prism:publicationName":[{"@language":"en","@value":"Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)"},{"@language":"ja","@value":"日本臨床外科学会雑誌"},{"@language":"en","@value":"Nihon Rinsho Geka Gakkai Zasshi (J Jpn Surg Assoc)"},{"@language":"en","@value":"J Jpn Surg Assoc"},{"@language":"en","@value":"J. Jpn. Surg. Assoc."},{"@language":"ja","@value":"日臨外会誌"},{"@language":"en","@value":"Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)"},{"@language":"ja","@value":"日本臨床外科学会雑誌"}],"dc:publisher":[{"@language":"en","@value":"Japan Surgical Association"},{"@language":"ja","@value":"日本臨床外科学会"}],"prism:publicationDate":"2007","prism:volume":"68","prism:number":"3","prism:startingPage":"654","prism:endingPage":"658"},"reviewed":"false","url":[{"@id":"http://www.jstage.jst.go.jp/article/jjsa/68/3/68_3_654/_pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2007294964"}],"availableAt":"2007","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=%E8%82%9D%E5%9A%A2%E8%83%9E%E6%80%A7%E8%85%AB%E7%98%8D","dc:title":"肝嚢胞性腫瘍"},{"@id":"https://cir.nii.ac.jp/all?q=%E8%82%9D%E5%9A%A2%E8%83%9E","dc:title":"肝嚢胞"},{"@id":"https://cir.nii.ac.jp/all?q=%E7%99%8C%E5%8C%96","dc:title":"癌化"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360292619212095488","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Biliary cystadenocarcinoma with peritoneal carcinomatosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262946373001728","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Hepatobiliary Cystadenoma and Cystadenocarcinoma"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951795354536320","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Intra-Hepatic Cystadenoma of Bile Duct Origin, with Malignant Alteration"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233268716996736","@type":"Article","relationType":["references","cites"],"jpcoar:relatedTitle":[{"@value":"Carcinoma arising in congenital cysts of the liver"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204848889472","@type":"Article","relationType":["isReferencedBy","isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A HEPATOBILIARY CYSTADENOMA WITH OVARIAN LIKE MESENCHYMAL STROMA; PREOPERATIVE DIAGNOSTIC UNCERTAINTY"},{"@language":"ja","@value":"術前診断に苦慮した卵巣様間質を伴った肝内胆管嚢胞腺腫の１例"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204912628096","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A Case of Biliary Cystadenocarcinoma."},{"@value":"胆管嚢胞腺癌の１例"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204917874688","@type":"Article","relationType":["isReferencedBy","isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A Resected Case of Liver Mucinous Cystadenoma Arising From Caudate Lobe"},{"@language":"ja","@value":"尾状葉原発肝粘液性嚢胞腺腫の１例"}]},{"@id":"https://cir.nii.ac.jp/crid/1570009750585258240","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Biliary cystadenocarcinoma with peritoneal carcinomatosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1570009750585268352","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"嚢腫形成型肝癌について"}]},{"@id":"https://cir.nii.ac.jp/crid/1570291225625846656","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@value":"胆管細胞癌をめぐる諸問題, 嚢胞性腺癌-成因と分類-"}]},{"@id":"https://cir.nii.ac.jp/crid/1570854176904447616","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"肝嚢胞穿刺細胞診により診断できた肝腺扁平上皮癌と肝嚢胞腺癌の各1例"},{"@language":"en","@value":"Rare cases of adenosquamous carcinoma of the liver and biliary cystadenocarcinoma diagnosed by aspiration cytology of cystic lesions of the liver"}]},{"@id":"https://cir.nii.ac.jp/crid/1573105975329082880","@type":"Article","relationType":["cites"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Intrahapatic cystadenoma of bile duct origin with malignant alteration. Report of a case, treated with total left hepatic lobectomy"}]}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:0029195911"},{"@type":"CROSSREF","@value":"10.3919/jjsa.68.654"},{"@type":"CIA","@value":"130004516493"},{"@type":"CIA","@value":"10019502992"},{"@type":"CROSSREF","@value":"10.5833/jjgs.42.382_references_DOI_7kUQcRgHfhs19pAV8McR7YidFNX"},{"@type":"CROSSREF","@value":"10.3919/jjsa.71.489_references_DOI_7kUQcRgHfhs19pAV8McR7YidFNX"}]}