Heterotopic bone formation in tumor stromal tissue. Immunohistochemical considerations.
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- KUMASA SHUNSUKE
- Department of Oral Surgery, Asahi University School of Dentistry
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- MORI HIROMITSU
- Department of Oral Surgery, Asahi University School of Dentistry
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- MORI MASAHIKO
- Department of Oral Surgery, Asahi University School of Dentistry
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- SHIBUTANI TOSHIAKI
- Department of Periodontology, Asahi University School of Dentistry
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- IWAYAMA YUKIO
- Department of Periodontology, Asahi University School of Dentistry
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- TSUJIMURA TAKAHIRO
- Department of Pathology, Sumitomo Hospital
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- OHNISHI TOMOKAZU
- Department of Biochemistry, Kagoshima University Dental School
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- ARAKAKI NAOKATSU
- Department of Biochemistry, Kagoshima University Dental School
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- NAKATA MINORU
- Department of Pediatric Dentistry, Faculty of Dentistry, Kyushu University
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- KURISU KOJIRO
- Department of Oral Anatomy, Faculty of Dentistry, Kyushu University
書誌事項
- タイトル別名
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- IMMUNOHISTOCHEMICAL CONSIDERATIONS
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説明
Ectopic and heterotopic bone formation rarely occur in stromal tissues of various epithelial tumors. In the present study, ectopic bone forming tumors; calcifying epithelioma Malherbe (6), renal cell carcinoma (1), thyroid adenocarcinoma (1) and ovary carcinoma (1) were examined. The process of ectopic bone formation could be classified into 1) bone formation related to epithelial tissue as found in calcifying epithelioma of Malherbe, 2) bone formation from perivascular smooth muscle, and 3) that due to metaplasia occurring in stromal connective tissue of epithelial tumors. Immunohistochemical detection of proteoglycans (PG) was made in bone-forming matrix areas, and these areas were positive for chondrotin 4 and 6 sulfate, and dermatan and heparan sulfate PGs. Immunohistochemically, fibronectin, collagen III and bone sialoprotein as matrix proteins, and carbonic anhydrase as calcification marker were tested and they appeared in these pre-calcifying tissues.
収録刊行物
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- Ａｃｔａ Ｈｉｓｔｏｃｈｅｍｉｃａ ｅｔ Ｃｙｔｏｃｈｅｍｉｃａ
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Ａｃｔａ Ｈｉｓｔｏｃｈｅｍｉｃａ ｅｔ Ｃｙｔｏｃｈｅｍｉｃａ 23 (4), 427-439, 1990
日本組織細胞化学会
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詳細情報 詳細情報について
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- CRID
- 1390282679838076160
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- NII論文ID
- 110003147542
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- NII書誌ID
- AA00508022
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- COI
- 1:CAS:528:DyaK3MXhsVSksL8%3D
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- ISSN
- 13475800
- 00445991
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- 本文言語コード
- en
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- データソース種別
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- JaLC
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- NDLデジコレ（旧NII-ELS）
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- 抄録ライセンスフラグ
- 使用不可