Adult T-cell Leukemia (ATL) Cells which Express Neural Cell Adhesion Molecule (NCAM) and Infiltrate into the Central Nervous System.

DOI Web Site Web Site PubMed 参考文献25件 オープンアクセス
  • HASHIGUCHI Teruto
    The Department of Internal Medicine, Kagoshima City Hospital The Department of Clinical Laboratory Medicine, Kagoshima University
  • TARA Mitsutoshi
    The Department of Internal Medicine, Kagoshima City Hospital
  • NIINA Kiyoshige
    The Department of Internal Medicine, Kagoshima City Hospital
  • HIGUCHI Itsuro
    The Third Department of Internal Medicine, Kagoshima University
  • ARIMURA Kimiyoshi
    The Third Department of Internal Medicine, Kagoshima University
  • OSAME Mitsuhiro
    The Third Department of Internal Medicine, Kagoshima University
  • MARUYAMA Ikuro
    The Department of Clinical Laboratory Medicine, Kagoshima University

書誌事項

タイトル別名
  • Adult T cell Leukemia ATL Cells which Express Neural Cell Adhesion Molecule NCAM and Infilitrate into the Central Nervous System
公開日
2002
資源種別
journal article
DOI
  • 10.2169/internalmedicine.41.34
公開者
一般社団法人 日本内科学会

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説明

We encountered a patient with adult T-cell leukemia/lymphoma (ATL) which expressed neural cell adhesion molecule (NCAM). The tumor cells markedly infiltrated the central nervous system (CNS) during the course of the ATL. The patient died 20 months after disease onset, which was considered to be early in the course. During the invasion of the CNS, the surface phenotype of the peripheral blood ATL cells by flow cytometric analysis was CD2+, CD3+, CD4+, CD7-, CD8-, CD16-, NCAM (CD56)+, HLA-DR-. We speculate that the infiltration of ATL cells into the CNS was closely related to the expression of the NCAM in this patient.<br>(Internal Medicine 41: 34-38, 2002)

収録刊行物

  • Internal Medicine

    Internal Medicine 41 (1), 34-38, 2002

    一般社団法人 日本内科学会

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