The Role of Intravenous Coronary Thrombolysis for Patients with Acute Myocardial Infarction in Different Treatment Strategies
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- Kobayashi Hiroshi
- Department of Cardiology, Tokyo Medical University Hachioji Medical Center
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- Takazawa Kenji
- Department of Cardiology, Tokyo Medical University Hachioji Medical Center
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- Matsumoto Chisa
- Department of Cardiology, Tokyo Medical University Hachioji Medical Center
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- Ooi Kuniomi
- Department of Cardiology, Tokyo Medical University Hachioji Medical Center
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- Nagata Takuya
- Department of Cardiology, Tokyo Medical University Hachioji Medical Center
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- Katou Kouta
- Department of Cardiology, Tokyo Medical University Hachioji Medical Center
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- Yoshida Masanobu
- Department of Cardiology, Tokyo Medical University Hachioji Medical Center
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- Aiga Mamoru
- Department of Cardiology, Tokyo Medical University Hachioji Medical Center
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- Aizawa Akira
- Department of Cardiology, Tokyo Medical University Hachioji Medical Center
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- Takahashi Eiji
- Department of Cardiology, Tokyo Medical University Hachioji Medical Center
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- Namatame Yasuhide
- Department of Cardiology, Tokyo Medical University Hachioji Medical Center
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- Kinou Mineko
- Department of Cardiology, Tokyo Medical University Hachioji Medical Center
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- Yamashina Akira
- Second Department Internal Medicine, Tokyo Medical University
書誌事項
- 公開日
- 2006
- DOI
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- 10.2169/internalmedicine.45.1576
- 公開者
- 一般社団法人 日本内科学会
この論文をさがす
説明
Objective: To examine acute-phase outcomes in acute myocardial infarction (AMI) according to different initial treatments.<br> Patients and Methods: This retrospective study involved 405 patients with AMI who had undergone coronary angiography during the acute phase. The patients were retrospectively examined by dividing into groups according to treatment received: intravenous coronary thrombolysis (IVCT) (n=83), intracoronary thrombolysis (ICT) (n=62), and percutaneous coronary intervention (PCI) (n=221).<br> Results: TIMI 3 flow at the initial angiography was higher in the IVCT group (P<0.05) at 32.5% in the IVCT group and 21.7% in the non-IVCT group. The time from onset to initiation of treatment was shorter in the IVCT group (P<0.001) at 227 min in the IVCT group, 337 min in the ICT group, and 479 min in the PCI group. The acute-phase mortality was lower in the IVCT group (P<0.05) at 2.4% in the IVCT group, 3.2% in the ICT group, and 11.8% in the PCI group. According to sub-analysis, the restenosis rate during the chronic phase after PCI did not differ with or without antecedent administration of a thrombolytic agent.<br> Conclusion: IVCT as an initial treatment for AMI enabled the fastest reperfusion at TIMI ≥2 flow, resulting in a good acute-phase outcome.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 45 (11), 709-714, 2006
一般社団法人 日本内科学会
