{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679849921152.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.2169/internalmedicine.52.9078"}},{"identifier":{"@type":"COI","@value":"1:CAS:528:DC%2BC3sXmvFejtLk%3D"}},{"identifier":{"@type":"PMID","@value":"23583993"}},{"identifier":{"@type":"HDL","@value":"http://hdl.handle.net/10091/17246"}},{"identifier":{"@type":"URI","@value":"https://soar-ir.repo.nii.ac.jp/records/3777"}},{"identifier":{"@type":"URI","@value":"https://www.jstage.jst.go.jp/article/internalmedicine/52/8/52_52.9078/_pdf"}},{"identifier":{"@type":"NAID","@value":"130003365996"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2014058900"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@language":"en","@value":"Two Siblings with Type 1 Autoimmune Pancreatitis"}],"dc:language":"en","description":[{"type":"abstract","notation":[{"@language":"en","@value":"Type 1 autoimmune pancreatitis (AIP) is characterized by a high serum IgG4 concentration and is closely associated with the <i>HLA-DRB1<sup>*</sup>04:05-DQB1<sup>*</sup>04:01</i> haplotype, for which family studies may disclose its immunogenetic significance. In the present study, we encountered two male siblings with type 1 AIP who exhibited diffuse pancreatic swelling with a capsule-like rim and diffuse pancreatic duct stricture. The younger brother also displayed characteristic IgG4-related sialadenitis and retroperitoneal fibrosis. Contrary to our expectations, the siblings showed only normal or slightly elevated values of serum IgG4 and no <i>HLA DRB1<sup>*</sup>04:05-DQB1<sup>*</sup>04:01</i> haplotype, suggesting that type 1 autoimmune pancreatitis is associated with multiple immunogenetic factors.<br>"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410282679849921159","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000240058602"}],"foaf:name":[{"@language":"en","@value":"Maruyama Masahiro"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Gastroenterology, Shinshu University School of Medicine, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679849921158","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000240058600"}],"foaf:name":[{"@language":"en","@value":"Watanabe Takayuki"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Gastroenterology, Shinshu University School of Medicine, 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Med."}],"dc:publisher":[{"@language":"en","@value":"The Japanese Society of Internal Medicine"},{"@language":"ja","@value":"一般社団法人 日本内科学会"}],"prism:publicationDate":"2013","prism:volume":"52","prism:number":"8","prism:startingPage":"895","prism:endingPage":"899"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"https://soar-ir.repo.nii.ac.jp/records/3777"},{"@id":"https://www.jstage.jst.go.jp/article/internalmedicine/52/8/52_52.9078/_pdf"},{"@id":"http://hdl.handle.net/10091/17246"},{"@id":"https://search.jamas.or.jp/link/ui/2014058900"}],"availableAt":"2013","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=autoimmune%20pancreatitis","dc:title":"autoimmune pancreatitis"},{"@id":"https://cir.nii.ac.jp/all?q=IgG4","dc:title":"IgG4"},{"@id":"https://cir.nii.ac.jp/all?q=sibling","dc:title":"sibling"}],"dcterms:subject":[{"subjectScheme":"Other","notation":[{"@value":"autoimmune 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