{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679891209088.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.2185/jjrm.64.853"}},{"identifier":{"@type":"NDL_BIB_ID","@value":"027135004"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/bib/027135004"}},{"identifier":{"@type":"URI","@value":"https://ndlsearch.ndl.go.jp/books/R000000004-I027135004"}},{"identifier":{"@type":"URI","@value":"https://www.jstage.jst.go.jp/article/jjrm/64/5/64_853/_pdf"}},{"identifier":{"@type":"NAID","@value":"130005138097"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2016234338"}}],"dc:title":[{"@language":"ja","@value":"集中治療室における侵襲性カンジダ感染症チェックリストを用いた抗真菌薬の使用実態調査"},{"@language":"en","@value":"Antifungal Medication in IC Unit Using Invasive Candidosis Checklist as Reference"},{"@language":"ja-Kana","@value":"シュウチュウ チリョウシツ ニ オケル シンシュウセイ カンジダ カンセンショウ チェックリスト オ モチイタ コウシンキンヤク ノ シヨウ ジッタイ チョウサ"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"Many patients carried into the emergency room or intensive care unit are suspected to have risk factors for deep-seated mycosis. Using the Actions Bundle, which itemizes diagnosis and treatment of invasive candidiasis, we carried out investigations into facts about the use of antifungal drugs in the intensive care unit of our hospital. The subjects of this retrospective study were 11 ICU patients who were given antifungal drugs intravenously between April 2013 and March 2014. Their medication records revealed that micafungin was administered to five patients, fosfluconazole to another five patients and fulconazole to the remaining one patient. The ratio of the cases where the dugs were used in compliance with what the Actions Bundle suggested worked out at 71.4±15.9%. When it came to the collection rate of two sets of blood culture and the proper dosage, the compliance rates were the lowest with 36% each. As regards dosage, 18% was excessive, 36% proper and 45% insufficient. As pharmacists in charge of the ICU, we have to use the checklist more effectively and intervene in the care of patients with invasive candidiasis at an early stage."},{"@language":"ja","@value":"救命・集中治療領域では, 深在性真菌症のリスク因子を複数有している患者が多い。深在性真菌症はほとんどがカンジダ属に起因し, 予後は極めて不良となる。今回, 侵襲性カンジダ感染症の診断・治療の具体的な方法が箇条書きに明記された「ACTIONsBUNDLE」を用いて, 集中治療室 (Intensive Care Unit: 以下, ICU) での抗真菌薬の使用実態を調査した。2013年4月から2014年3月までに, 抗真菌薬が経静脈的に投与されたICU入室患者を対象とし, 診療録より後方視的に調査した。対象患者は11例, 抗真菌薬の内訳はミカファンギン5例, ホスフルコナゾール5例, フルコナゾール1例, 原因真菌はC. albicans5例, C. tropicalis1例, C. glabrata1例であった。江南厚生病院ICUにおける「ACTIONsBUNDLE」の遵守率は71.4±15.9%で, 抗真菌薬投与前の血液培養2セット採取率, 適切な投与量での実施率はともに36% (4／11) で最も低かった。投与量に関しては過量18% (2／11), 適切36% (4／11), 不足45% (5／11) であった。ICU担当薬剤師として, チェックリストを有効活用し, 予後が極めて不良である侵襲性カンジダ感染症の治療へ早期に関与していく必要がある。"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410282679891209091","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000317564042"}],"foaf:name":[{"@language":"ja","@value":"有満 征伸"},{"@language":"en","@value":"ARIMITSU Masanobu"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Dept. of Pharmacy, Konan Kosei Hospital"},{"@language":"ja","@value":"江南厚生病院薬剤部"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679891209093","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000317564043"}],"foaf:name":[{"@language":"ja","@value":"佐々 英也"},{"@language":"en","@value":"SASSA Hideya"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Dept. of Pharmacy, Konan Kosei Hospital"},{"@language":"ja","@value":"江南厚生病院薬剤部"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679891209090","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000317564044"}],"foaf:name":[{"@language":"ja","@value":"内山 耕作"},{"@language":"en","@value":"UCHIYAMA Kousaku"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Dept. of Pharmacy, Konan Kosei Hospital"},{"@language":"ja","@value":"江南厚生病院薬剤部"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679891209092","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000317564045"}],"foaf:name":[{"@language":"ja","@value":"鈴川 誠"},{"@language":"en","@value":"SUZUKAWA Makoto"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Dept. of Pharmacy, Konan Kosei Hospital"},{"@language":"ja","@value":"江南厚生病院薬剤部"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679891209088","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000317564046"}],"foaf:name":[{"@language":"ja","@value":"大榮 薫"},{"@language":"en","@value":"OHE Kaoru"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Dept. of Pharmacy, Konan Kosei Hospital"},{"@language":"ja","@value":"江南厚生病院薬剤部"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679891209094","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000317564047"}],"foaf:name":[{"@language":"ja","@value":"野村 賢一"},{"@language":"en","@value":"NOMURA Kenichi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Dept. of Pharmacy, Konan Kosei Hospital"},{"@language":"ja","@value":"江南厚生病院薬剤部"}]},{"@id":"https://cir.nii.ac.jp/crid/1410282679891209089","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000317564048"}],"foaf:name":[{"@language":"ja","@value":"野田 直樹"},{"@language":"en","@value":"NODA Naoki"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Dept. of Pharmacy, Konan Kosei Hospital"},{"@language":"ja","@value":"江南厚生病院薬剤部"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"04682513"},{"@type":"LISSN","@value":"04682513"},{"@type":"EISSN","@value":"13497421"},{"@type":"NDL_BIB_ID","@value":"000000018806"},{"@type":"ISSN","@value":"04682513"},{"@type":"NCID","@value":"AN00196216"}],"prism:publicationName":[{"@language":"en","@value":"JOURNAL OF THE JAPANESE ASSOCIATION OF RURAL MEDICINE"},{"@language":"ja","@value":"日本農村医学会雑誌"},{"@language":"en","@value":"J.J.R.M."},{"@language":"ja","@value":"日農医誌"},{"@language":"en","@value":"J. J. R. M."}],"dc:publisher":[{"@language":"en","@value":"THE JAPANESE ASSOCIATION OF RURAL MEDICINE"},{"@language":"ja","@value":"一般社団法人 日本農村医学会"}],"prism:publicationDate":"2016","prism:volume":"64","prism:number":"5","prism:startingPage":"853","prism:endingPage":"859"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"http://id.ndl.go.jp/bib/027135004"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I027135004"},{"@id":"https://www.jstage.jst.go.jp/article/jjrm/64/5/64_853/_pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2016234338"}],"availableAt":"2016","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=%E6%8A%97%E7%9C%9F%E8%8F%8C%E8%96%AC","dc:title":"抗真菌薬"},{"@id":"https://cir.nii.ac.jp/all?q=ICU","dc:title":"ICU"},{"@id":"https://cir.nii.ac.jp/all?q=ACTIONs%20BUNDLE","dc:title":"ACTIONs BUNDLE"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360292618819324544","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Outcomes with micafungin in patients with candidaemia or invasive candidiasis due to Candida glabrata and Candida krusei"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292621481984896","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Micafungin versus liposomal amphotericin B for candidaemia and invasive candidosis: a phase III randomised double-blind trial"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855571542956672","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Optimal Testing Parameters for Blood Cultures"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233269981898880","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Clinical factors associated with fluconazole resistance and short-term survival in patients with Candida bloodstream infection"}]}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:2000916823"},{"@type":"NDL_SEARCH","@value":"oai:ndlsearch.ndl.go.jp:R000000004-I027135004"},{"@type":"CROSSREF","@value":"10.2185/jjrm.64.853"},{"@type":"CIA","@value":"130005138097"},{"@type":"OPENAIRE","@value":"doi_dedup___::ac97474b3f294b27b56349cb53705777"}]}