{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390282679938416640.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.11392/jsao1972.4.14"}},{"identifier":{"@type":"NAID","@value":"130001729281"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/1975083133"}}],"dc:title":[{"@language":"en","@value":"Feasibility of ethylene-vinyl acetate copolymers as biomedical material."},{"@value":"エチレン―酢酸ビニル共重合体の"}],"dcterms:alternative":[{"@value":"医用高分子材料としての可能性について"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"As part of the work to develop safer soft polymeric materials for medical use ethylene-vinyl acetate copolymers (EVA) were evaluated by physico-chemical and biological tests. Test materials were extracted in distilled water at 37°, 70° or 100°C. The extracts obtained were submitted to determining the amount of potassium permanganate-reducing substance, and the absorbance of ultraviolet absorption at 220mμ. Hemolytic activity was studied in two ways by exposing canine red blood cell to plastic surface, and to the extract that was prepared by extraction of test material in physiological saline solution. EVA showed very low level of teachable ingredients and hemolysis compared with Tygon. Antithrombogenicity of EVA was similar to that of silicone rubber. EVA was implanted subcutaneously in a dog for one year. Tensile strength and infrared absorption spectrum of the implanted film were practically unchanged. These results suggest that EVA is feasible as a safer soft material in biomedical applications."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1030003658328180231","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"30126263"},{"@type":"NRID","@value":"1000030126263"},{"@type":"NRID","@value":"9000021736647"},{"@type":"NRID","@value":"9000021284022"},{"@type":"NRID","@value":"9000258104112"},{"@type":"NRID","@value":"9000002278520"},{"@type":"NRID","@value":"9000021700126"},{"@type":"NRID","@value":"9000253358756"},{"@type":"NRID","@value":"9000397866306"},{"@type":"NRID","@value":"9000008351165"},{"@type":"NRID","@value":"9000003157485"},{"@type":"NRID","@value":"9000021684574"},{"@type":"NRID","@value":"9000021766226"},{"@type":"NRID","@value":"9000391825319"},{"@type":"NRID","@value":"9000243897168"},{"@type":"NRID","@value":"9000398788132"},{"@type":"NRID","@value":"9000254933133"},{"@type":"NRID","@value":"9000004598020"},{"@type":"NRID","@value":"9000006574012"},{"@type":"NRID","@value":"9000391418302"},{"@type":"NRID","@value":"9000254397803"},{"@type":"NRID","@value":"9000021228569"},{"@type":"NRID","@value":"9000282424097"},{"@type":"NRID","@value":"9000254398842"},{"@type":"NRID","@value":"9000391827038"},{"@type":"NRID","@value":"9000391826055"},{"@type":"NRID","@value":"9000391817091"},{"@type":"NRID","@value":"9000003744248"},{"@type":"NRID","@value":"9000282405943"},{"@type":"NRID","@value":"9000021712463"},{"@type":"NRID","@value":"9000391410726"},{"@type":"NRID","@value":"9000254932607"},{"@type":"NRID","@value":"9000004582037"},{"@type":"NRID","@value":"9000021740305"},{"@type":"NRID","@value":"9000021800265"},{"@type":"NRID","@value":"9000367015471"},{"@type":"NRID","@value":"9000021829238"},{"@type":"NRID","@value":"9000345337399"},{"@type":"NRID","@value":"9000008696605"},{"@type":"NRID","@value":"9000021734809"},{"@type":"NRID","@value":"9000021728429"},{"@type":"NRID","@value":"9000391413190"},{"@type":"NRID","@value":"9000256044810"},{"@type":"NRID","@value":"9000021721142"},{"@type":"NRID","@value":"9000253354924"},{"@type":"NRID","@value":"9000002889091"},{"@type":"NRID","@value":"9000021806766"},{"@type":"NRID","@value":"9000021685223"},{"@type":"NRID","@value":"9000021683012"},{"@type":"NRID","@value":"9000391828764"},{"@type":"NRID","@value":"9000253299996"},{"@type":"NRID","@value":"9000253300205"},{"@type":"NRID","@value":"9000252840894"},{"@type":"NRID","@value":"9000022444222"},{"@type":"NRID","@value":"9000391410992"},{"@type":"NRID","@value":"9000016946420"},{"@type":"NRID","@value":"9000009845749"},{"@type":"NRID","@value":"9000021749432"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0007947"}],"foaf:name":[{"@language":"en","@value":"WATANABE 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Organs"}],"dc:publisher":[{"@language":"en","@value":"JAPANESE SOCIETY FOR ARTIFICIAL ORGANS"},{"@language":"ja","@value":"一般社団法人 日本人工臓器学会"}],"prism:publicationDate":"1975","prism:volume":"4","prism:number":"1","prism:startingPage":"14","prism:endingPage":"18"},"url":[{"@id":"https://search.jamas.or.jp/link/ui/1975083133"}],"availableAt":"1975","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=%E3%82%A8%E3%83%81%E3%83%AC%E3%83%B3%E2%80%95%E9%85%A2%E9%85%B8%E3%83%93%E3%83%8B%E3%83%AB%E5%85%B1%E9%87%8D%E5%90%88%E4%BD%93","dc:title":"エチレン―酢酸ビニル共重合体"},{"@id":"https://cir.nii.ac.jp/all?q=%E8%BB%9F%E8%B3%AA%E5%8C%BB%E7%94%A8%E9%AB%98%E5%88%86%E5%AD%90%E6%9D%90%E6%96%99","dc:title":"軟質医用高分子材料"},{"@id":"https://cir.nii.ac.jp/all?q=%E6%BA%B6%E5%87%BA%E7%89%A9%E8%A9%A6%E9%A8%93","dc:title":"溶出物試験"},{"@id":"https://cir.nii.ac.jp/all?q=%E6%BA%B6%E8%A1%80%E6%80%A7%E8%A9%A6%E9%A8%93","dc:title":"溶血性試験"},{"@id":"https://cir.nii.ac.jp/all?q=%E7%94%9F%E4%BD%93%E9%81%A9%E5%90%88%E6%80%A7","dc:title":"生体適合性"}],"dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:0038080856"},{"@type":"CIA","@value":"130001729281"}]}